Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.domaniend.2020.106579 http://hdl.handle.net/11449/209756 |
Resumo: | This study examined the effects of exogenous hCG administration on ovarian function and pregnancy rates in estrous-induced dairy goats during the transition into the breeding season. Eighty-six Toggenburg does received 60 mg of medroxyprogesterone acetate intravaginal sponge for 6 d plus 200 IU of equine chorionic gonadotropin and 30 mg of d-cloprostenol i.m. 24 h before sponge removal, and were then bred for 96 h. Seven days (D7) after first mating the does received either 1 mL of saline (the control group, n = 43) or 300 IU of hCG (the hCG-treated group, n = 43) i.m. Transrectal ovarian ultrasonography (B-mode and color Doppler) was performed on D7, D13, D17, and D21 and ultrasonographic pregnancy detection on D30. Pregnancy rate was higher (P < 0.05) in hCG-treated goats (90.7%; 39/43) than that in control animals (74.4%; 32/43). Accessory luteal structures (ALSs) were detected in 46.5% (20/43) of hCG-treated does. All hCG-treated does that had ALSs and 82.6% of goats without ALS post-treatment remained pregnant. The total luteal area increased (P < 0.05) from D7 to D13 in pregnant animals of both groups, whereas mean vascular area declined (P < 0.05) by D21 in all nonpregnant does. Serum progesterone concentrations increased (P < 0.05) on D21 in pregnant goats of both groups, but they were related to changes in luteal tissue content only in control does throughout the present study. Mean daily numbers of small- and medium-sized antral follicles decreased (P < 0.05) only in pregnant animals of both groups with a decline in medium follicle numbers occurring earlier in hCG-treated (D13) compared with control does (D17). To summarize, a single dose of hCG given on D7 after estrus was followed by a decrease in the number of medium-sized antral follicles in gestating hCG-treated does, induced the formation of ALSs in similar to 47% of all hCG-treated does, and significantly increased the pregnancy rate in estrous-induced Toggenburg goats in the transition to the breeding season. (C) 2020 Elsevier Inc. All rights reserved. |
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Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanismConception rateGoathCGOvaryProgesteroneUltrasonographyThis study examined the effects of exogenous hCG administration on ovarian function and pregnancy rates in estrous-induced dairy goats during the transition into the breeding season. Eighty-six Toggenburg does received 60 mg of medroxyprogesterone acetate intravaginal sponge for 6 d plus 200 IU of equine chorionic gonadotropin and 30 mg of d-cloprostenol i.m. 24 h before sponge removal, and were then bred for 96 h. Seven days (D7) after first mating the does received either 1 mL of saline (the control group, n = 43) or 300 IU of hCG (the hCG-treated group, n = 43) i.m. Transrectal ovarian ultrasonography (B-mode and color Doppler) was performed on D7, D13, D17, and D21 and ultrasonographic pregnancy detection on D30. Pregnancy rate was higher (P < 0.05) in hCG-treated goats (90.7%; 39/43) than that in control animals (74.4%; 32/43). Accessory luteal structures (ALSs) were detected in 46.5% (20/43) of hCG-treated does. All hCG-treated does that had ALSs and 82.6% of goats without ALS post-treatment remained pregnant. The total luteal area increased (P < 0.05) from D7 to D13 in pregnant animals of both groups, whereas mean vascular area declined (P < 0.05) by D21 in all nonpregnant does. Serum progesterone concentrations increased (P < 0.05) on D21 in pregnant goats of both groups, but they were related to changes in luteal tissue content only in control does throughout the present study. Mean daily numbers of small- and medium-sized antral follicles decreased (P < 0.05) only in pregnant animals of both groups with a decline in medium follicle numbers occurring earlier in hCG-treated (D13) compared with control does (D17). To summarize, a single dose of hCG given on D7 after estrus was followed by a decrease in the number of medium-sized antral follicles in gestating hCG-treated does, induced the formation of ALSs in similar to 47% of all hCG-treated does, and significantly increased the pregnancy rate in estrous-induced Toggenburg goats in the transition to the breeding season. (C) 2020 Elsevier Inc. All rights reserved.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)EMBRAPAFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)Univ Fed Fluminense, Fac Vet, Rua Vital Brasil Filho 64, Niteroi, RJ, BrazilUniv Grande Rio, Fac Med Vet, Rua Prof Jose de Souza Herdy 1160, Duque De Caxias, RJ, BrazilUniv Presidente Antonio Carlos, Av Juiz de Fora 1100, Juiz De Fora, MG, BrazilEmbrapa Caprinos & Ovinos, Rodovia MG 133,Km 42, Coronel Pacheco, MG, BrazilSao Paulo State Univ, Dept Prevent Vet Med & Anim Reprod, Via Acesso Prof Paulo Donato Castelane S-N, Jaboticabal, SP, BrazilUniv Guelph, Ontario Vet Coll, Dept Biomed Sci, Guelph, ON N1G 2W1, CanadaSao Paulo State Univ, Dept Prevent Vet Med & Anim Reprod, Via Acesso Prof Paulo Donato Castelane S-N, Jaboticabal, SP, BrazilCNPq: 314952/2018-7EMBRAPA: 20.19.01.004.00.03.001FAPEMIG: CVZPPM-000201-17Elsevier B.V.Universidade Federal Fluminense (UFF)Univ Grande RioUniv Presidente Antonio CarlosEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)Universidade Estadual Paulista (Unesp)Univ GuelphCortes, L. R.Souza-Fabjan, J. M. G.Dias, D. S.Martins, B. B.Maia, A. L. R. S.Veiga, M. O.Arashiro, E. K. N.Brandao, F. Z.Oliveira, M. E. F. [UNESP]Bartlewski, P. M.Fonseca, J. F.2021-06-25T12:28:15Z2021-06-25T12:28:15Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article12http://dx.doi.org/10.1016/j.domaniend.2020.106579Domestic Animal Endocrinology. New York: Elsevier Science Inc, v. 74, 12 p., 2021.0739-7240http://hdl.handle.net/11449/20975610.1016/j.domaniend.2020.106579WOS:000597156100003Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengDomestic Animal Endocrinologyinfo:eu-repo/semantics/openAccess2024-06-06T18:10:26Zoai:repositorio.unesp.br:11449/209756Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:39:51.430246Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism |
title |
Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism |
spellingShingle |
Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism Cortes, L. R. Conception rate Goat hCG Ovary Progesterone Ultrasonography |
title_short |
Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism |
title_full |
Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism |
title_fullStr |
Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism |
title_full_unstemmed |
Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism |
title_sort |
Administration of a single dose of 300 IU of human chorionic gonadotropin seven days after the onset of estrus improves pregnancy rate in dairy goats by an unknown mechanism |
author |
Cortes, L. R. |
author_facet |
Cortes, L. R. Souza-Fabjan, J. M. G. Dias, D. S. Martins, B. B. Maia, A. L. R. S. Veiga, M. O. Arashiro, E. K. N. Brandao, F. Z. Oliveira, M. E. F. [UNESP] Bartlewski, P. M. Fonseca, J. F. |
author_role |
author |
author2 |
Souza-Fabjan, J. M. G. Dias, D. S. Martins, B. B. Maia, A. L. R. S. Veiga, M. O. Arashiro, E. K. N. Brandao, F. Z. Oliveira, M. E. F. [UNESP] Bartlewski, P. M. Fonseca, J. F. |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal Fluminense (UFF) Univ Grande Rio Univ Presidente Antonio Carlos Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA) Universidade Estadual Paulista (Unesp) Univ Guelph |
dc.contributor.author.fl_str_mv |
Cortes, L. R. Souza-Fabjan, J. M. G. Dias, D. S. Martins, B. B. Maia, A. L. R. S. Veiga, M. O. Arashiro, E. K. N. Brandao, F. Z. Oliveira, M. E. F. [UNESP] Bartlewski, P. M. Fonseca, J. F. |
dc.subject.por.fl_str_mv |
Conception rate Goat hCG Ovary Progesterone Ultrasonography |
topic |
Conception rate Goat hCG Ovary Progesterone Ultrasonography |
description |
This study examined the effects of exogenous hCG administration on ovarian function and pregnancy rates in estrous-induced dairy goats during the transition into the breeding season. Eighty-six Toggenburg does received 60 mg of medroxyprogesterone acetate intravaginal sponge for 6 d plus 200 IU of equine chorionic gonadotropin and 30 mg of d-cloprostenol i.m. 24 h before sponge removal, and were then bred for 96 h. Seven days (D7) after first mating the does received either 1 mL of saline (the control group, n = 43) or 300 IU of hCG (the hCG-treated group, n = 43) i.m. Transrectal ovarian ultrasonography (B-mode and color Doppler) was performed on D7, D13, D17, and D21 and ultrasonographic pregnancy detection on D30. Pregnancy rate was higher (P < 0.05) in hCG-treated goats (90.7%; 39/43) than that in control animals (74.4%; 32/43). Accessory luteal structures (ALSs) were detected in 46.5% (20/43) of hCG-treated does. All hCG-treated does that had ALSs and 82.6% of goats without ALS post-treatment remained pregnant. The total luteal area increased (P < 0.05) from D7 to D13 in pregnant animals of both groups, whereas mean vascular area declined (P < 0.05) by D21 in all nonpregnant does. Serum progesterone concentrations increased (P < 0.05) on D21 in pregnant goats of both groups, but they were related to changes in luteal tissue content only in control does throughout the present study. Mean daily numbers of small- and medium-sized antral follicles decreased (P < 0.05) only in pregnant animals of both groups with a decline in medium follicle numbers occurring earlier in hCG-treated (D13) compared with control does (D17). To summarize, a single dose of hCG given on D7 after estrus was followed by a decrease in the number of medium-sized antral follicles in gestating hCG-treated does, induced the formation of ALSs in similar to 47% of all hCG-treated does, and significantly increased the pregnancy rate in estrous-induced Toggenburg goats in the transition to the breeding season. (C) 2020 Elsevier Inc. All rights reserved. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T12:28:15Z 2021-06-25T12:28:15Z 2021-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.domaniend.2020.106579 Domestic Animal Endocrinology. New York: Elsevier Science Inc, v. 74, 12 p., 2021. 0739-7240 http://hdl.handle.net/11449/209756 10.1016/j.domaniend.2020.106579 WOS:000597156100003 |
url |
http://dx.doi.org/10.1016/j.domaniend.2020.106579 http://hdl.handle.net/11449/209756 |
identifier_str_mv |
Domestic Animal Endocrinology. New York: Elsevier Science Inc, v. 74, 12 p., 2021. 0739-7240 10.1016/j.domaniend.2020.106579 WOS:000597156100003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Domestic Animal Endocrinology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
12 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129540958978048 |