High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program

Detalhes bibliográficos
Autor(a) principal: Moreto, Fernando [UNESP]
Data de Publicação: 2017
Outros Autores: de França, Natasha A. G. [UNESP], Gondo, Fernanda F. [UNESP], Callegari, Aliucha [UNESP], Corrente, José E. [UNESP], Burini, Roberto C. [UNESP], de Oliveira, Erick P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1186/s41110-017-0043-0
http://hdl.handle.net/11449/228592
Resumo: Background: Phase angle (PhA) value is a useful tool for identifying cell membrane integrity dysfunction. It is known that metabolic syndrome (MetS) increases oxidative stress and inflammation; and consequently can promote cellular damage. We hypothesized that MetS and inflammatory blood markers could be associated with lower PhA values. Therefore, the aim of this study was to identify the association of PhA values with MetS and blood markers in individuals clinically screened for a lifestyle modification program. Methods: In a cross-sectional study, 417 selected subjects (76 men and 341 women, 53.9 ± 9.4 years old) were evaluated. Assessments included clinics, anthropometric measures, body composition by bioimpedance, and laboratory blood markers, including plasma lipids, glucose, and C-reactive protein concentrations. According to the PhA median values, subjects were classified in low (≤6.3°) and high (>6.3°) PhA groups. Results: Subjects with lower PhA values were older and showed lower body mass index, waist circumference, muscle mass index, creatinine, and uric acid; and higher gamma-GT and HDL cholesterol. Neither the presence of MetS nor the presence of the increasing number of MetS components was associated with PhA values. The logistic regression analysis adjusted for age, gender, body mass index, and muscle mass index showed that higher C-reactive protein concentrations (>3.0 mg/L) increased the odds of low PhA values (OR = 1.62; CI = 1.01–2.60). Conclusion: Higher C-reactive protein concentrations increased the odds of low PhA independently of the presence of MetS. Additionally, contrary to our hypothesis, MetS was not associated with PhA values.
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spelling High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification programBioimpedanceInflammationPhase angleBackground: Phase angle (PhA) value is a useful tool for identifying cell membrane integrity dysfunction. It is known that metabolic syndrome (MetS) increases oxidative stress and inflammation; and consequently can promote cellular damage. We hypothesized that MetS and inflammatory blood markers could be associated with lower PhA values. Therefore, the aim of this study was to identify the association of PhA values with MetS and blood markers in individuals clinically screened for a lifestyle modification program. Methods: In a cross-sectional study, 417 selected subjects (76 men and 341 women, 53.9 ± 9.4 years old) were evaluated. Assessments included clinics, anthropometric measures, body composition by bioimpedance, and laboratory blood markers, including plasma lipids, glucose, and C-reactive protein concentrations. According to the PhA median values, subjects were classified in low (≤6.3°) and high (>6.3°) PhA groups. Results: Subjects with lower PhA values were older and showed lower body mass index, waist circumference, muscle mass index, creatinine, and uric acid; and higher gamma-GT and HDL cholesterol. Neither the presence of MetS nor the presence of the increasing number of MetS components was associated with PhA values. The logistic regression analysis adjusted for age, gender, body mass index, and muscle mass index showed that higher C-reactive protein concentrations (>3.0 mg/L) increased the odds of low PhA values (OR = 1.62; CI = 1.01–2.60). Conclusion: Higher C-reactive protein concentrations increased the odds of low PhA independently of the presence of MetS. Additionally, contrary to our hypothesis, MetS was not associated with PhA values.Centre for Physical Exercise and Nutrition Metabolism UNESP School of Medicine Public Health DepartmentDepartment of Nutrition School of Public Health Sao Paulo UniversityDepartment of Bioestatistic-Bioscience Institute (UNESP)School of Medicine Federal University of UberlandiaCentre for Physical Exercise and Nutrition Metabolism UNESP School of Medicine Public Health DepartmentDepartment of Bioestatistic-Bioscience Institute (UNESP)Universidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)Universidade Federal de Uberlândia (UFU)Moreto, Fernando [UNESP]de França, Natasha A. G. [UNESP]Gondo, Fernanda F. [UNESP]Callegari, Aliucha [UNESP]Corrente, José E. [UNESP]Burini, Roberto C. [UNESP]de Oliveira, Erick P.2022-04-29T08:27:32Z2022-04-29T08:27:32Z2017-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1186/s41110-017-0043-0Nutrire, v. 42, n. 1, 2017.2316-78741519-8928http://hdl.handle.net/11449/22859210.1186/s41110-017-0043-02-s2.0-85053031905Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengNutrireinfo:eu-repo/semantics/openAccess2022-04-29T08:27:33Zoai:repositorio.unesp.br:11449/228592Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:51:56.741571Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program
title High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program
spellingShingle High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program
Moreto, Fernando [UNESP]
Bioimpedance
Inflammation
Phase angle
title_short High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program
title_full High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program
title_fullStr High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program
title_full_unstemmed High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program
title_sort High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program
author Moreto, Fernando [UNESP]
author_facet Moreto, Fernando [UNESP]
de França, Natasha A. G. [UNESP]
Gondo, Fernanda F. [UNESP]
Callegari, Aliucha [UNESP]
Corrente, José E. [UNESP]
Burini, Roberto C. [UNESP]
de Oliveira, Erick P.
author_role author
author2 de França, Natasha A. G. [UNESP]
Gondo, Fernanda F. [UNESP]
Callegari, Aliucha [UNESP]
Corrente, José E. [UNESP]
Burini, Roberto C. [UNESP]
de Oliveira, Erick P.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Universidade de São Paulo (USP)
Universidade Federal de Uberlândia (UFU)
dc.contributor.author.fl_str_mv Moreto, Fernando [UNESP]
de França, Natasha A. G. [UNESP]
Gondo, Fernanda F. [UNESP]
Callegari, Aliucha [UNESP]
Corrente, José E. [UNESP]
Burini, Roberto C. [UNESP]
de Oliveira, Erick P.
dc.subject.por.fl_str_mv Bioimpedance
Inflammation
Phase angle
topic Bioimpedance
Inflammation
Phase angle
description Background: Phase angle (PhA) value is a useful tool for identifying cell membrane integrity dysfunction. It is known that metabolic syndrome (MetS) increases oxidative stress and inflammation; and consequently can promote cellular damage. We hypothesized that MetS and inflammatory blood markers could be associated with lower PhA values. Therefore, the aim of this study was to identify the association of PhA values with MetS and blood markers in individuals clinically screened for a lifestyle modification program. Methods: In a cross-sectional study, 417 selected subjects (76 men and 341 women, 53.9 ± 9.4 years old) were evaluated. Assessments included clinics, anthropometric measures, body composition by bioimpedance, and laboratory blood markers, including plasma lipids, glucose, and C-reactive protein concentrations. According to the PhA median values, subjects were classified in low (≤6.3°) and high (>6.3°) PhA groups. Results: Subjects with lower PhA values were older and showed lower body mass index, waist circumference, muscle mass index, creatinine, and uric acid; and higher gamma-GT and HDL cholesterol. Neither the presence of MetS nor the presence of the increasing number of MetS components was associated with PhA values. The logistic regression analysis adjusted for age, gender, body mass index, and muscle mass index showed that higher C-reactive protein concentrations (>3.0 mg/L) increased the odds of low PhA values (OR = 1.62; CI = 1.01–2.60). Conclusion: Higher C-reactive protein concentrations increased the odds of low PhA independently of the presence of MetS. Additionally, contrary to our hypothesis, MetS was not associated with PhA values.
publishDate 2017
dc.date.none.fl_str_mv 2017-12-01
2022-04-29T08:27:32Z
2022-04-29T08:27:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1186/s41110-017-0043-0
Nutrire, v. 42, n. 1, 2017.
2316-7874
1519-8928
http://hdl.handle.net/11449/228592
10.1186/s41110-017-0043-0
2-s2.0-85053031905
url http://dx.doi.org/10.1186/s41110-017-0043-0
http://hdl.handle.net/11449/228592
identifier_str_mv Nutrire, v. 42, n. 1, 2017.
2316-7874
1519-8928
10.1186/s41110-017-0043-0
2-s2.0-85053031905
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Nutrire
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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