Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.foodres.2019.108559 http://hdl.handle.net/11449/190492 |
Resumo: | Ethanolic extracts of propolis are consumed for their health benefits even though direct consumption of alcoholic extracts is not always ideal. Natural Deep Eutectic Solvents (NADES) can potentially extract similar compounds as alcoholic extracts while being better for direct consumption. Therefore, in this work alternative solvents for the extraction of green propolis including its biomarker artepillin C were examined. Sixteen NADES made from low toxicity chemicals, including the essential amino acid L-lysine, were explored along with twelve individual NADES components and honey, which showed similar physical-chemical properties to NADES. At 50 °C NADES made from choline chloride-propylene glycol or lactic acid proved to be equal or better than the benchmark EtOH:Water 7:3 (v/v). Alternatively, aqueous L-lysine appeared as a potential solvent for the preparation of aqueous propolis extracts. From these findings NADES, honey and aqueous L-lysine solutions all demonstrated the potential to replace ethanol or water for extracting green propolis. |
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Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolisAlternative solventsArtepillin CGreen liquid chromatographyGreen solventsLow transition temperature mixturesPropolis from Baccharis dracunculifoliaEthanolic extracts of propolis are consumed for their health benefits even though direct consumption of alcoholic extracts is not always ideal. Natural Deep Eutectic Solvents (NADES) can potentially extract similar compounds as alcoholic extracts while being better for direct consumption. Therefore, in this work alternative solvents for the extraction of green propolis including its biomarker artepillin C were examined. Sixteen NADES made from low toxicity chemicals, including the essential amino acid L-lysine, were explored along with twelve individual NADES components and honey, which showed similar physical-chemical properties to NADES. At 50 °C NADES made from choline chloride-propylene glycol or lactic acid proved to be equal or better than the benchmark EtOH:Water 7:3 (v/v). Alternatively, aqueous L-lysine appeared as a potential solvent for the preparation of aqueous propolis extracts. From these findings NADES, honey and aqueous L-lysine solutions all demonstrated the potential to replace ethanol or water for extracting green propolis.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)São Paulo State University (UNESP) Faculty of Agricultural SciencesUniversity of South Australia (UniSA) Future Industries InstituteFederal University of São Carlos (UFSCar) Department of ChemistrySão Paulo State University (UNESP) Institute of ChemistrySão Paulo State University (UNESP) Faculty of Agricultural SciencesSão Paulo State University (UNESP) Institute of ChemistryFAPESP: 2013/07600-3FAPESP: 2013/15086-8FAPESP: 2016/50009-2FAPESP: 2017/06216-6Universidade Estadual Paulista (Unesp)Future Industries InstituteUniversidade Federal de São Carlos (UFSCar)Funari, Cristiano Soleo [UNESP]Sutton, Adam T.Carneiro, Renato LajarimFraige, Karina [UNESP]Cavalheiro, Alberto José [UNESP]da Silva Bolzani, Vanderlan [UNESP]Hilder, Emily F.Arrua, R. Dario2019-10-06T17:14:58Z2019-10-06T17:14:58Z2019-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.foodres.2019.108559Food Research International, v. 125.1873-71450963-9969http://hdl.handle.net/11449/19049210.1016/j.foodres.2019.1085592-s2.0-85068965050Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFood Research Internationalinfo:eu-repo/semantics/openAccess2021-10-23T14:26:58Zoai:repositorio.unesp.br:11449/190492Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T14:26:58Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis |
title |
Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis |
spellingShingle |
Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis Funari, Cristiano Soleo [UNESP] Alternative solvents Artepillin C Green liquid chromatography Green solvents Low transition temperature mixtures Propolis from Baccharis dracunculifolia |
title_short |
Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis |
title_full |
Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis |
title_fullStr |
Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis |
title_full_unstemmed |
Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis |
title_sort |
Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis |
author |
Funari, Cristiano Soleo [UNESP] |
author_facet |
Funari, Cristiano Soleo [UNESP] Sutton, Adam T. Carneiro, Renato Lajarim Fraige, Karina [UNESP] Cavalheiro, Alberto José [UNESP] da Silva Bolzani, Vanderlan [UNESP] Hilder, Emily F. Arrua, R. Dario |
author_role |
author |
author2 |
Sutton, Adam T. Carneiro, Renato Lajarim Fraige, Karina [UNESP] Cavalheiro, Alberto José [UNESP] da Silva Bolzani, Vanderlan [UNESP] Hilder, Emily F. Arrua, R. Dario |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Future Industries Institute Universidade Federal de São Carlos (UFSCar) |
dc.contributor.author.fl_str_mv |
Funari, Cristiano Soleo [UNESP] Sutton, Adam T. Carneiro, Renato Lajarim Fraige, Karina [UNESP] Cavalheiro, Alberto José [UNESP] da Silva Bolzani, Vanderlan [UNESP] Hilder, Emily F. Arrua, R. Dario |
dc.subject.por.fl_str_mv |
Alternative solvents Artepillin C Green liquid chromatography Green solvents Low transition temperature mixtures Propolis from Baccharis dracunculifolia |
topic |
Alternative solvents Artepillin C Green liquid chromatography Green solvents Low transition temperature mixtures Propolis from Baccharis dracunculifolia |
description |
Ethanolic extracts of propolis are consumed for their health benefits even though direct consumption of alcoholic extracts is not always ideal. Natural Deep Eutectic Solvents (NADES) can potentially extract similar compounds as alcoholic extracts while being better for direct consumption. Therefore, in this work alternative solvents for the extraction of green propolis including its biomarker artepillin C were examined. Sixteen NADES made from low toxicity chemicals, including the essential amino acid L-lysine, were explored along with twelve individual NADES components and honey, which showed similar physical-chemical properties to NADES. At 50 °C NADES made from choline chloride-propylene glycol or lactic acid proved to be equal or better than the benchmark EtOH:Water 7:3 (v/v). Alternatively, aqueous L-lysine appeared as a potential solvent for the preparation of aqueous propolis extracts. From these findings NADES, honey and aqueous L-lysine solutions all demonstrated the potential to replace ethanol or water for extracting green propolis. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T17:14:58Z 2019-10-06T17:14:58Z 2019-11-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.foodres.2019.108559 Food Research International, v. 125. 1873-7145 0963-9969 http://hdl.handle.net/11449/190492 10.1016/j.foodres.2019.108559 2-s2.0-85068965050 |
url |
http://dx.doi.org/10.1016/j.foodres.2019.108559 http://hdl.handle.net/11449/190492 |
identifier_str_mv |
Food Research International, v. 125. 1873-7145 0963-9969 10.1016/j.foodres.2019.108559 2-s2.0-85068965050 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Food Research International |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964861124313088 |