Luminescent Pb-free perovskites: low-cytotoxicity materials for primary thermal sensing

• Autor(a) principal: Passini, Luan N.
• Data de Publicação: 2023
• Outros Autores: Maturi, Fernando E. [UNESP], Pugina, Roberta S., Hilário, Eloísa G., Fontes, Marina, Barud, Hernane S., Carlos, Luís D., Caiut, José Maurício A., Manzani, Danilo
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1039/d3tc00768e; http://hdl.handle.net/11449/247566

Selecting a suitable host matrix to perform temperature sensing in biomedical applications requires low cytotoxicity, facile synthesis, and an ability to be doped with light-emitting ions. With this perspective, indium-based halide double perovskites, specifically Cs2AgIn0.9Bi0.1Cl6, Cs2Ag0.6Na0.4InCl6, and Cs2Ag0.6Na0.4In0.9Bi0.1Cl6, were chosen as host materials to develop lanthanide-based primary thermometers due to their low phonon energy and ease of synthesis. The incorporation of Na+ and Bi3+ into the perovskite cubic crystal lattice was confirmed by X-ray diffraction and Raman spectroscopy while the optical properties of both the undoped and Yb3+/Er3+ co-doped perovskites were assessed by diffuse reflectance and photoluminescence spectroscopies. The obtained perovskite samples demonstrated excellent thermal stability, with the ability to withstand temperatures as high as 500 °C. A temperature-dependent green emission of Er3+ was observed in the co-doped samples upon 980 nm irradiation, yielding a relative thermal sensitivity and uncertainty in temperature values of 1.3% K−1 and 0.3 K, respectively. Incorporating the obtained perovskites (0.05 to 0.20 mg mL−1) into L2929 cells as an in vitro model resulted in high cell viability, underscoring the benefits of selecting such a low-cytotoxicity material for applications in biological media.