Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1002/celc.202000329 http://hdl.handle.net/11449/200454 |
Resumo: | A molecularly imprinted polymer (MIP)-based electrochemical sensor was developed for the monitoring of hydrochlorothiazide (HCT) in dialysate and hemodialysis wastewater. The MIP was constructed by the electropolymerization of ortho-phenylenediamine on multi-walled carbon nanotube modified glassy carbon electrode surface. The experimental optimization was carried out by Plackett-Burman design screening and central composite design. Through square wave voltammetry (SWV) analysis, the sensor presented linear response in the range of 5.0×10−6 to 1.0×10−4 mol L−1 (R=0.9995) and detection limit of 3.2×10−6 mol L−1. The film morphology was investigated by SEM, EDX and AFM, and the electrochemical response was confirmed by EIS. The MIP film exhibited excellent selectivity for HCT, rapid response and good practicability. The sensor was successfully applied for direct and selective determination of HCT in dialysate and hemodialysis wastewater samples with recovery rates ranging from 97 % to 102 % based on the standard addition method. |
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Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewaterelectrochemical sensorexperimental designhemodialysishydrochlorothiazidemolecularly imprinted polymers.A molecularly imprinted polymer (MIP)-based electrochemical sensor was developed for the monitoring of hydrochlorothiazide (HCT) in dialysate and hemodialysis wastewater. The MIP was constructed by the electropolymerization of ortho-phenylenediamine on multi-walled carbon nanotube modified glassy carbon electrode surface. The experimental optimization was carried out by Plackett-Burman design screening and central composite design. Through square wave voltammetry (SWV) analysis, the sensor presented linear response in the range of 5.0×10−6 to 1.0×10−4 mol L−1 (R=0.9995) and detection limit of 3.2×10−6 mol L−1. The film morphology was investigated by SEM, EDX and AFM, and the electrochemical response was confirmed by EIS. The MIP film exhibited excellent selectivity for HCT, rapid response and good practicability. The sensor was successfully applied for direct and selective determination of HCT in dialysate and hemodialysis wastewater samples with recovery rates ranging from 97 % to 102 % based on the standard addition method.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Analytical Chemistry Department Institute of Chemistry São Paulo State University (Unesp), Araraquara 14800-060National Institute of Alternative Technologies for Detection Toxicological Assessment and Removal of Micropollutants and Radioactive Substances (INCT-DATREM), Araraquara 14800-060Analytical Chemistry Department Institute of Chemistry São Paulo State University (Unesp), Araraquara 14800-060FAPESP: 2014/50945-4Universidade Estadual Paulista (Unesp)Toxicological Assessment and Removal of Micropollutants and Radioactive Substances (INCT-DATREM)de Oliveira, Gabriela F. [UNESP]Hudari, Felipe F. [UNESP]Pereira, Fabíola M. V. [UNESP]Zanoni, Maria V. B. [UNESP]da Silva, José L. [UNESP]2020-12-12T02:07:06Z2020-12-12T02:07:06Z2020-07-16info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article3006-3016http://dx.doi.org/10.1002/celc.202000329ChemElectroChem, v. 7, n. 14, p. 3006-3016, 2020.2196-0216http://hdl.handle.net/11449/20045410.1002/celc.2020003292-s2.0-8508512896357044454736540240000-0002-8117-2108Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengChemElectroCheminfo:eu-repo/semantics/openAccess2021-10-23T12:40:04Zoai:repositorio.unesp.br:11449/200454Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:29:12.008672Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater |
title |
Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater |
spellingShingle |
Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater de Oliveira, Gabriela F. [UNESP] electrochemical sensor experimental design hemodialysis hydrochlorothiazide molecularly imprinted polymers. |
title_short |
Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater |
title_full |
Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater |
title_fullStr |
Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater |
title_full_unstemmed |
Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater |
title_sort |
Carbon Nanotube-Based Molecularly Imprinted Voltammetric Sensor for Selective Diuretic Analysis of Dialysate and Hemodialysis Wastewater |
author |
de Oliveira, Gabriela F. [UNESP] |
author_facet |
de Oliveira, Gabriela F. [UNESP] Hudari, Felipe F. [UNESP] Pereira, Fabíola M. V. [UNESP] Zanoni, Maria V. B. [UNESP] da Silva, José L. [UNESP] |
author_role |
author |
author2 |
Hudari, Felipe F. [UNESP] Pereira, Fabíola M. V. [UNESP] Zanoni, Maria V. B. [UNESP] da Silva, José L. [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Toxicological Assessment and Removal of Micropollutants and Radioactive Substances (INCT-DATREM) |
dc.contributor.author.fl_str_mv |
de Oliveira, Gabriela F. [UNESP] Hudari, Felipe F. [UNESP] Pereira, Fabíola M. V. [UNESP] Zanoni, Maria V. B. [UNESP] da Silva, José L. [UNESP] |
dc.subject.por.fl_str_mv |
electrochemical sensor experimental design hemodialysis hydrochlorothiazide molecularly imprinted polymers. |
topic |
electrochemical sensor experimental design hemodialysis hydrochlorothiazide molecularly imprinted polymers. |
description |
A molecularly imprinted polymer (MIP)-based electrochemical sensor was developed for the monitoring of hydrochlorothiazide (HCT) in dialysate and hemodialysis wastewater. The MIP was constructed by the electropolymerization of ortho-phenylenediamine on multi-walled carbon nanotube modified glassy carbon electrode surface. The experimental optimization was carried out by Plackett-Burman design screening and central composite design. Through square wave voltammetry (SWV) analysis, the sensor presented linear response in the range of 5.0×10−6 to 1.0×10−4 mol L−1 (R=0.9995) and detection limit of 3.2×10−6 mol L−1. The film morphology was investigated by SEM, EDX and AFM, and the electrochemical response was confirmed by EIS. The MIP film exhibited excellent selectivity for HCT, rapid response and good practicability. The sensor was successfully applied for direct and selective determination of HCT in dialysate and hemodialysis wastewater samples with recovery rates ranging from 97 % to 102 % based on the standard addition method. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T02:07:06Z 2020-12-12T02:07:06Z 2020-07-16 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1002/celc.202000329 ChemElectroChem, v. 7, n. 14, p. 3006-3016, 2020. 2196-0216 http://hdl.handle.net/11449/200454 10.1002/celc.202000329 2-s2.0-85085128963 5704445473654024 0000-0002-8117-2108 |
url |
http://dx.doi.org/10.1002/celc.202000329 http://hdl.handle.net/11449/200454 |
identifier_str_mv |
ChemElectroChem, v. 7, n. 14, p. 3006-3016, 2020. 2196-0216 10.1002/celc.202000329 2-s2.0-85085128963 5704445473654024 0000-0002-8117-2108 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
ChemElectroChem |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
3006-3016 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128519157317632 |