Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/s11695-019-03989-z http://hdl.handle.net/11449/189349 |
Resumo: | Objective: To investigate the influence of changes in energy balance and body composition on the rate of weight loss throughout 1 year of Roux-en-Y gastric bypass. Methods: Variables were collected pre-, 6, and 12 months (M) post-surgery from 18 women (BMI ≥ 40 and ≤ 50 kg m−2, 20 to 45 years). Total energy expenditure (TEEm), fat-free mass (FFM), and fat mass (FM) were measured by doubly labeled water. Self-reported energy intake (EIsr) was obtained from three non-consecutive food diaries. Metabolic adaptation was assessed via deviations from TEE predictive equation, and the calculated energy intake (EIc) via the sum of TEE and change in body stores. Results: BMI significantly decreased (mean ± SD) from 45 ± 2 kg m−2 to 32 ± 3 kg m−2 at 6 M, and to 30 ± 3 kg m−2 at 12 M after surgery. The TEEm reduced significantly at both time points when compared with pre-surgery (6 M: − 612 ± 317 kcal day−1; 12 M: − 447 ± 516 kcal day−1). At 6 M, a metabolic adaptation was observed and the energy balance was − 1151 ± 195 kcal day−1, while at 12 M it was − 332 ± 158 kcal day−1. Changes in the values of TEEm were associated with changes in body weight at 12 M post-surgery. A significant underreporting was observed for EIsr (1057 ± 385 kcal day−1) vs. EIc (2083 ± 309 kcal day−1) at 12 M post-operative. Conclusion: The higher rate of weight loss at 6 M post-surgery was a response to energy imbalance, which was caused by high restriction in energy intake even with the presence of metabolic adaptation at this time. The EIsr was not sufficiently accurate to assess the energy consumption of this population. Registration of Clinical Trials (Observational Study): Brazilian Clinical Trials Registry: RBR-8k5jsj. Universal Trial Number: U1111-1206-0858. |
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Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water StudyBariatric surgeryBody compositionDoubly labeled waterEnergy balanceMetabolic adaptationObjective: To investigate the influence of changes in energy balance and body composition on the rate of weight loss throughout 1 year of Roux-en-Y gastric bypass. Methods: Variables were collected pre-, 6, and 12 months (M) post-surgery from 18 women (BMI ≥ 40 and ≤ 50 kg m−2, 20 to 45 years). Total energy expenditure (TEEm), fat-free mass (FFM), and fat mass (FM) were measured by doubly labeled water. Self-reported energy intake (EIsr) was obtained from three non-consecutive food diaries. Metabolic adaptation was assessed via deviations from TEE predictive equation, and the calculated energy intake (EIc) via the sum of TEE and change in body stores. Results: BMI significantly decreased (mean ± SD) from 45 ± 2 kg m−2 to 32 ± 3 kg m−2 at 6 M, and to 30 ± 3 kg m−2 at 12 M after surgery. The TEEm reduced significantly at both time points when compared with pre-surgery (6 M: − 612 ± 317 kcal day−1; 12 M: − 447 ± 516 kcal day−1). At 6 M, a metabolic adaptation was observed and the energy balance was − 1151 ± 195 kcal day−1, while at 12 M it was − 332 ± 158 kcal day−1. Changes in the values of TEEm were associated with changes in body weight at 12 M post-surgery. A significant underreporting was observed for EIsr (1057 ± 385 kcal day−1) vs. EIc (2083 ± 309 kcal day−1) at 12 M post-operative. Conclusion: The higher rate of weight loss at 6 M post-surgery was a response to energy imbalance, which was caused by high restriction in energy intake even with the presence of metabolic adaptation at this time. The EIsr was not sufficiently accurate to assess the energy consumption of this population. Registration of Clinical Trials (Observational Study): Brazilian Clinical Trials Registry: RBR-8k5jsj. Universal Trial Number: U1111-1206-0858.School of Pharmaceutical Sciences Sao Paulo State University – UNESP, Rodovia Araraquara Jaú, Km 01, s/n. Bairro: Campos VilleDepartment of Neurology University of Wisconsin – Madison, 1685 Highland Avenue, Medical Foundation Centennial Building, 7th FloorBiotechnology Center University of Wisconsin – Madison, 425 Henry Mall StreetRibeirao Preto Medical School University of Sao Paulo – USP, Avenida Bandeirantes, 3900 - Bairro: Monte AlegreStable Isotope Center Bioscience Institute Sao Paulo State University – UNESP, Rua Prof. Dr. Antônio Celso Wagner Zanin, 250 - Bairro: Distrito de Rubião JuniorEducation Department Institute of Biosciences Sao Paulo State University – UNESP, Rua Prof. Dr. Antônio Celso Wagner Zanin, 250 - Bairro: Distrito de Rubião JuniorSchool of Pharmaceutical Sciences Sao Paulo State University – UNESP, Rodovia Araraquara Jaú, Km 01, s/n. Bairro: Campos VilleStable Isotope Center Bioscience Institute Sao Paulo State University – UNESP, Rua Prof. Dr. Antônio Celso Wagner Zanin, 250 - Bairro: Distrito de Rubião JuniorEducation Department Institute of Biosciences Sao Paulo State University – UNESP, Rua Prof. Dr. Antônio Celso Wagner Zanin, 250 - Bairro: Distrito de Rubião JuniorUniversidade Estadual Paulista (Unesp)University of Wisconsin – MadisonUniversidade de São Paulo (USP)Novaes Ravelli, Michele [UNESP]Schoeller, Dale A.Crisp, Alex Harley [UNESP]Shriver, TimothyFerriolli, EduardoDucatti, Carlos [UNESP]Marques de Oliveira, Maria Rita [UNESP]2019-10-06T16:37:46Z2019-10-06T16:37:46Z2019-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1007/s11695-019-03989-zObesity Surgery.1708-04280960-8923http://hdl.handle.net/11449/18934910.1007/s11695-019-03989-z2-s2.0-85068168728Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengObesity Surgeryinfo:eu-repo/semantics/openAccess2021-10-22T21:09:58Zoai:repositorio.unesp.br:11449/189349Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-22T21:09:58Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study |
title |
Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study |
spellingShingle |
Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study Novaes Ravelli, Michele [UNESP] Bariatric surgery Body composition Doubly labeled water Energy balance Metabolic adaptation |
title_short |
Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study |
title_full |
Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study |
title_fullStr |
Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study |
title_full_unstemmed |
Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study |
title_sort |
Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study |
author |
Novaes Ravelli, Michele [UNESP] |
author_facet |
Novaes Ravelli, Michele [UNESP] Schoeller, Dale A. Crisp, Alex Harley [UNESP] Shriver, Timothy Ferriolli, Eduardo Ducatti, Carlos [UNESP] Marques de Oliveira, Maria Rita [UNESP] |
author_role |
author |
author2 |
Schoeller, Dale A. Crisp, Alex Harley [UNESP] Shriver, Timothy Ferriolli, Eduardo Ducatti, Carlos [UNESP] Marques de Oliveira, Maria Rita [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) University of Wisconsin – Madison Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Novaes Ravelli, Michele [UNESP] Schoeller, Dale A. Crisp, Alex Harley [UNESP] Shriver, Timothy Ferriolli, Eduardo Ducatti, Carlos [UNESP] Marques de Oliveira, Maria Rita [UNESP] |
dc.subject.por.fl_str_mv |
Bariatric surgery Body composition Doubly labeled water Energy balance Metabolic adaptation |
topic |
Bariatric surgery Body composition Doubly labeled water Energy balance Metabolic adaptation |
description |
Objective: To investigate the influence of changes in energy balance and body composition on the rate of weight loss throughout 1 year of Roux-en-Y gastric bypass. Methods: Variables were collected pre-, 6, and 12 months (M) post-surgery from 18 women (BMI ≥ 40 and ≤ 50 kg m−2, 20 to 45 years). Total energy expenditure (TEEm), fat-free mass (FFM), and fat mass (FM) were measured by doubly labeled water. Self-reported energy intake (EIsr) was obtained from three non-consecutive food diaries. Metabolic adaptation was assessed via deviations from TEE predictive equation, and the calculated energy intake (EIc) via the sum of TEE and change in body stores. Results: BMI significantly decreased (mean ± SD) from 45 ± 2 kg m−2 to 32 ± 3 kg m−2 at 6 M, and to 30 ± 3 kg m−2 at 12 M after surgery. The TEEm reduced significantly at both time points when compared with pre-surgery (6 M: − 612 ± 317 kcal day−1; 12 M: − 447 ± 516 kcal day−1). At 6 M, a metabolic adaptation was observed and the energy balance was − 1151 ± 195 kcal day−1, while at 12 M it was − 332 ± 158 kcal day−1. Changes in the values of TEEm were associated with changes in body weight at 12 M post-surgery. A significant underreporting was observed for EIsr (1057 ± 385 kcal day−1) vs. EIc (2083 ± 309 kcal day−1) at 12 M post-operative. Conclusion: The higher rate of weight loss at 6 M post-surgery was a response to energy imbalance, which was caused by high restriction in energy intake even with the presence of metabolic adaptation at this time. The EIsr was not sufficiently accurate to assess the energy consumption of this population. Registration of Clinical Trials (Observational Study): Brazilian Clinical Trials Registry: RBR-8k5jsj. Universal Trial Number: U1111-1206-0858. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T16:37:46Z 2019-10-06T16:37:46Z 2019-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s11695-019-03989-z Obesity Surgery. 1708-0428 0960-8923 http://hdl.handle.net/11449/189349 10.1007/s11695-019-03989-z 2-s2.0-85068168728 |
url |
http://dx.doi.org/10.1007/s11695-019-03989-z http://hdl.handle.net/11449/189349 |
identifier_str_mv |
Obesity Surgery. 1708-0428 0960-8923 10.1007/s11695-019-03989-z 2-s2.0-85068168728 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Obesity Surgery |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965547492802560 |