Utilização de programa de domínio público na análise da densidade radiográfica óssea digital de mandíbula de ratos submetidos ao alcoolismo crônico e consumo de fluoreto de sódio

• Autor(a) principal: Simas, Maria Carolina de Oliveira [UNESP]
• Data de Publicação: 2015
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/149662; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2017-01-30/000869245.pdf
• topic: Densitometria; Alcoolismo; Fluoreto de sódio; Radiografia dentária digital; Densitometry

The chronic use of alcohol has been identified as a risk factor in the development of osteoporosis by interfering in bone metabolism and reported in the literature show the use of fluoride therapy to reduce the risk of bone fractures in osteoporosis. This research aims to investigate the effects of sodium fluoride and chronic consumption of sugarcane brandy in bone tissue of rats jaw using radiographic density obtained in the digital radiographic image. In the experiment were used 105 rats distributed into five groups, as administered liquid diet: Group C control (water), Group F (fluoride), CA Group (water and alcohol), Group FA (fluoride and alcohol), CF Group (fluoride for 30 days). All animals received commercial feed. In Groups C and F animals were treated with water and fluoride ad libitum, respectively, for a period of 90 days. The CA and FA groups received respectively, water and fluoride for 30 days before the release of cane brandy solution (40ºGL) ad libitum in increasing concentrations of 30% and 60% for 20 days, after which received sugarcane liquor pure for 40 days until euthanasia of the animal. In the CF group animals received water for 60 days and then fluoride for 30 days. Animals were sacrificed after 3, 10 and 28 days of completion of the diet, hemimandibles were dissected and fixed in 10% formalin for 48 hours. The animals had to hemimandible imaged with routine technique for analyzing the radiographic density of the bones in the computer program Image J® (public domain), alongside an aluminum penetrometer, with steps with area 5x25mm², used as reference densidométrico. The software Image J™ was used to assess, in predetermined area (area of the alveolar bone below to the first molar, the condyle, the mandibular branch) the density level, grayscale, bones and penetrometer steps of aluminum. The values...