Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1038/s41598-018-20602-y http://hdl.handle.net/11449/179565 |
Resumo: | Carvacrol and linalool are natural compounds extracted from plants and are known for their insecticidal and repellent activities, respectively. However, their low aqueous solubility, high photosensitivity, and high volatility restrict their application in the control of agricultural pests. The encapsulation of volatile compounds can be an effective way of overcoming such problems. Inclusion complexes between beta-cyclodextrin (β-CD) and carvacrol (CVC) or linalool (LNL) were investigated. Inclusion complexes were prepared by the kneading method. Both complexes presented 1:1 host:guest stoichiometry and the highest affinity constants were observed at 20 °C for both molecules. The nanoparticles containing carvacrol and linalool had mean diameters of 175.2 and 245.8 nm, respectively and high encapsulation efficiencies (<90%) were achieved for both compounds. Biological assays with mites (Tetranychus urticae) showed that the nanoparticles possessed repellency, acaricidal, and oviposition activities against this organism. Nanoencapsulated carvacrol and linalool were significantly more effective in terms of acaricidal and oviposition activities, while the unencapsulated compounds showed better repellency activity. The nanoformulations prepared in this study are good candidates for the sustainable and effective use of botanical compounds in agriculture, contributing to the reduction of environmental contamination, as well as promoting the effective control of pests in agriculture. |
id |
UNSP_99291a7f3ea25b33c2e11f2b674457fd |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/179565 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticidesCarvacrol and linalool are natural compounds extracted from plants and are known for their insecticidal and repellent activities, respectively. However, their low aqueous solubility, high photosensitivity, and high volatility restrict their application in the control of agricultural pests. The encapsulation of volatile compounds can be an effective way of overcoming such problems. Inclusion complexes between beta-cyclodextrin (β-CD) and carvacrol (CVC) or linalool (LNL) were investigated. Inclusion complexes were prepared by the kneading method. Both complexes presented 1:1 host:guest stoichiometry and the highest affinity constants were observed at 20 °C for both molecules. The nanoparticles containing carvacrol and linalool had mean diameters of 175.2 and 245.8 nm, respectively and high encapsulation efficiencies (<90%) were achieved for both compounds. Biological assays with mites (Tetranychus urticae) showed that the nanoparticles possessed repellency, acaricidal, and oviposition activities against this organism. Nanoencapsulated carvacrol and linalool were significantly more effective in terms of acaricidal and oviposition activities, while the unencapsulated compounds showed better repellency activity. The nanoformulations prepared in this study are good candidates for the sustainable and effective use of botanical compounds in agriculture, contributing to the reduction of environmental contamination, as well as promoting the effective control of pests in agriculture.Department of Environmental Engineering São Paulo State University (UNESP)Department of Biochemistry and Tissue Biology State University of CampinasSão Paulo State University (UNESP) College of Agricultural and Veterinary SciencesDepartment of Environmental Engineering São Paulo State University (UNESP)São Paulo State University (UNESP) College of Agricultural and Veterinary SciencesUniversidade Estadual Paulista (Unesp)Universidade Estadual de Campinas (UNICAMP)Campos, Estefânia V.R. [UNESP]Proença, Patrícia L.F. [UNESP]Oliveira, Jhones L. [UNESP]Melville, Cirano C. [UNESP]Vechia, Jaqueline F. Della [UNESP]De Andrade, Daniel J. [UNESP]Fraceto, Leonardo F. [UNESP]2018-12-11T17:35:41Z2018-12-11T17:35:41Z2018-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1038/s41598-018-20602-yScientific Reports, v. 8, n. 1, 2018.2045-2322http://hdl.handle.net/11449/17956510.1038/s41598-018-20602-y2-s2.0-850416158102-s2.0-85041615810.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengScientific Reports1,533info:eu-repo/semantics/openAccess2023-11-27T06:14:42Zoai:repositorio.unesp.br:11449/179565Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:51:43.906274Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides |
title |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides |
spellingShingle |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides Campos, Estefânia V.R. [UNESP] |
title_short |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides |
title_full |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides |
title_fullStr |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides |
title_full_unstemmed |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides |
title_sort |
Chitosan nanoparticles functionalized with β-cyclodextrin: A promising carrier for botanical pesticides |
author |
Campos, Estefânia V.R. [UNESP] |
author_facet |
Campos, Estefânia V.R. [UNESP] Proença, Patrícia L.F. [UNESP] Oliveira, Jhones L. [UNESP] Melville, Cirano C. [UNESP] Vechia, Jaqueline F. Della [UNESP] De Andrade, Daniel J. [UNESP] Fraceto, Leonardo F. [UNESP] |
author_role |
author |
author2 |
Proença, Patrícia L.F. [UNESP] Oliveira, Jhones L. [UNESP] Melville, Cirano C. [UNESP] Vechia, Jaqueline F. Della [UNESP] De Andrade, Daniel J. [UNESP] Fraceto, Leonardo F. [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Estadual de Campinas (UNICAMP) |
dc.contributor.author.fl_str_mv |
Campos, Estefânia V.R. [UNESP] Proença, Patrícia L.F. [UNESP] Oliveira, Jhones L. [UNESP] Melville, Cirano C. [UNESP] Vechia, Jaqueline F. Della [UNESP] De Andrade, Daniel J. [UNESP] Fraceto, Leonardo F. [UNESP] |
description |
Carvacrol and linalool are natural compounds extracted from plants and are known for their insecticidal and repellent activities, respectively. However, their low aqueous solubility, high photosensitivity, and high volatility restrict their application in the control of agricultural pests. The encapsulation of volatile compounds can be an effective way of overcoming such problems. Inclusion complexes between beta-cyclodextrin (β-CD) and carvacrol (CVC) or linalool (LNL) were investigated. Inclusion complexes were prepared by the kneading method. Both complexes presented 1:1 host:guest stoichiometry and the highest affinity constants were observed at 20 °C for both molecules. The nanoparticles containing carvacrol and linalool had mean diameters of 175.2 and 245.8 nm, respectively and high encapsulation efficiencies (<90%) were achieved for both compounds. Biological assays with mites (Tetranychus urticae) showed that the nanoparticles possessed repellency, acaricidal, and oviposition activities against this organism. Nanoencapsulated carvacrol and linalool were significantly more effective in terms of acaricidal and oviposition activities, while the unencapsulated compounds showed better repellency activity. The nanoformulations prepared in this study are good candidates for the sustainable and effective use of botanical compounds in agriculture, contributing to the reduction of environmental contamination, as well as promoting the effective control of pests in agriculture. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-11T17:35:41Z 2018-12-11T17:35:41Z 2018-12-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1038/s41598-018-20602-y Scientific Reports, v. 8, n. 1, 2018. 2045-2322 http://hdl.handle.net/11449/179565 10.1038/s41598-018-20602-y 2-s2.0-85041615810 2-s2.0-85041615810.pdf |
url |
http://dx.doi.org/10.1038/s41598-018-20602-y http://hdl.handle.net/11449/179565 |
identifier_str_mv |
Scientific Reports, v. 8, n. 1, 2018. 2045-2322 10.1038/s41598-018-20602-y 2-s2.0-85041615810 2-s2.0-85041615810.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Scientific Reports 1,533 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128992422658048 |