Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1080/10790268.2020.1752976 http://hdl.handle.net/11449/198758 |
Resumo: | Objective: To compare the effects of intensity-matched acute exercise at different intensities on proinflammatory and anti-inflammatory cytokines between able-bodied (AB) and spinal cord injured (SCI) individuals. Design: Non-Randomized Controlled Trial. Setting: Community settings in São Paulo–Brazil. Participants: Eight AB and nine SCI paraplegic. Interventions: Participants underwent three exercise sessions at different relative intensities: at ventilatory threshold 1 intensity (VT1), 15% below VT1, and 15% above VT1. Similar energy expenditures were established from exercises with different intensities for each volunteer. The AB group was tested on a conventional treadmill, whereas the SCI group was tested on a treadmill adapted for wheelchair use. Blood samples were collected at baseline, immediately after, and 30 min after the exercise sessions. Outcome measures: Interleukin 1 receptor antagonist, interleukin 1 beta, interleukin 2, interleukin 4, interleukin 6, interleukin 10 and tumoral necrosis factor alpha were measured. Results: When groups were compared, interleukin–2 was found higher, whereas interleukin–4 and interleukin–10 were found lower in the SCI group at all collection times in the three exercise intensities (all P < 0.05). Interleukin–1 receptor antagonist was found higher immediately after exercise at VT1, 15% above VT1 and 30 min after 15% below VT1 in the AB group (all P < 0.05). In the AB group, an increase in interleukin–6 immediately after the exercise at VT1 compared with baseline was found (P = 0.01). Conclusion: Individuals with SCI may have to perform physical exercise at a higher volume or energy expenditure than AB individuals to obtain similar anti-inflammatory benefits of acute exercise. Trial registration: Uniform Trial Number identifier: U1111-1232-8142. |
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Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individualsAcute physical exerciseCytokinesInflammationRehabilitationSpinal cord injuriesObjective: To compare the effects of intensity-matched acute exercise at different intensities on proinflammatory and anti-inflammatory cytokines between able-bodied (AB) and spinal cord injured (SCI) individuals. Design: Non-Randomized Controlled Trial. Setting: Community settings in São Paulo–Brazil. Participants: Eight AB and nine SCI paraplegic. Interventions: Participants underwent three exercise sessions at different relative intensities: at ventilatory threshold 1 intensity (VT1), 15% below VT1, and 15% above VT1. Similar energy expenditures were established from exercises with different intensities for each volunteer. The AB group was tested on a conventional treadmill, whereas the SCI group was tested on a treadmill adapted for wheelchair use. Blood samples were collected at baseline, immediately after, and 30 min after the exercise sessions. Outcome measures: Interleukin 1 receptor antagonist, interleukin 1 beta, interleukin 2, interleukin 4, interleukin 6, interleukin 10 and tumoral necrosis factor alpha were measured. Results: When groups were compared, interleukin–2 was found higher, whereas interleukin–4 and interleukin–10 were found lower in the SCI group at all collection times in the three exercise intensities (all P < 0.05). Interleukin–1 receptor antagonist was found higher immediately after exercise at VT1, 15% above VT1 and 30 min after 15% below VT1 in the AB group (all P < 0.05). In the AB group, an increase in interleukin–6 immediately after the exercise at VT1 compared with baseline was found (P = 0.01). Conclusion: Individuals with SCI may have to perform physical exercise at a higher volume or energy expenditure than AB individuals to obtain similar anti-inflammatory benefits of acute exercise. Trial registration: Uniform Trial Number identifier: U1111-1232-8142.Departamento de Ciências da Saúde Universidade Estadual de Santa Cruz–(UESC)Departamento de Psicobiologia Universidade Federal de São Paulo–(UNIFESP)Centro de Estudos em Psicobiologia e Exercício - CEPEDepartment of Physical Education Universidade Estadual Paulista (UNESP)Instituto Federal de Educação Ciência e Tecnologia do Tocantins Campus AraguatinsFaculty of Health Sciences University of SydneyDepartamento de Biociências e Fisiopatologia Universidade Estadual de Maringá–UEMEscola de Educação Física Fisioterapia e Terapia Ocupacional Universidade Federal de Minas Gerais - UFMGDepartment of Physical Education Universidade Estadual Paulista (UNESP)Universidade Estadual de Santa Cruz–(UESC)Universidade Federal de São Paulo (UNIFESP)Centro de Estudos em Psicobiologia e Exercício - CEPEUniversidade Estadual Paulista (Unesp)Ciência e Tecnologia do TocantinsUniversity of SydneyUniversidade Estadual de Maringá (UEM)Universidade Federal de Minas Gerais (UFMG)Alves, Eduardo da Silvados Santos, Ronaldo Vagner Thomatielede Lira, Fábio Santos [UNESP]Almeida, Alexandre AparecidoEdwards, KateBenvenutti, MateusTufik, SergioDe Mello, Marco Túlio2020-12-12T01:21:13Z2020-12-12T01:21:13Z2020-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1080/10790268.2020.1752976Journal of Spinal Cord Medicine.2045-77231079-0268http://hdl.handle.net/11449/19875810.1080/10790268.2020.17529762-s2.0-85083678603Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Spinal Cord Medicineinfo:eu-repo/semantics/openAccess2021-10-22T20:11:23Zoai:repositorio.unesp.br:11449/198758Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:44:10.167288Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals |
title |
Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals |
spellingShingle |
Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals Alves, Eduardo da Silva Acute physical exercise Cytokines Inflammation Rehabilitation Spinal cord injuries |
title_short |
Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals |
title_full |
Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals |
title_fullStr |
Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals |
title_full_unstemmed |
Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals |
title_sort |
Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals |
author |
Alves, Eduardo da Silva |
author_facet |
Alves, Eduardo da Silva dos Santos, Ronaldo Vagner Thomatiele de Lira, Fábio Santos [UNESP] Almeida, Alexandre Aparecido Edwards, Kate Benvenutti, Mateus Tufik, Sergio De Mello, Marco Túlio |
author_role |
author |
author2 |
dos Santos, Ronaldo Vagner Thomatiele de Lira, Fábio Santos [UNESP] Almeida, Alexandre Aparecido Edwards, Kate Benvenutti, Mateus Tufik, Sergio De Mello, Marco Túlio |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual de Santa Cruz–(UESC) Universidade Federal de São Paulo (UNIFESP) Centro de Estudos em Psicobiologia e Exercício - CEPE Universidade Estadual Paulista (Unesp) Ciência e Tecnologia do Tocantins University of Sydney Universidade Estadual de Maringá (UEM) Universidade Federal de Minas Gerais (UFMG) |
dc.contributor.author.fl_str_mv |
Alves, Eduardo da Silva dos Santos, Ronaldo Vagner Thomatiele de Lira, Fábio Santos [UNESP] Almeida, Alexandre Aparecido Edwards, Kate Benvenutti, Mateus Tufik, Sergio De Mello, Marco Túlio |
dc.subject.por.fl_str_mv |
Acute physical exercise Cytokines Inflammation Rehabilitation Spinal cord injuries |
topic |
Acute physical exercise Cytokines Inflammation Rehabilitation Spinal cord injuries |
description |
Objective: To compare the effects of intensity-matched acute exercise at different intensities on proinflammatory and anti-inflammatory cytokines between able-bodied (AB) and spinal cord injured (SCI) individuals. Design: Non-Randomized Controlled Trial. Setting: Community settings in São Paulo–Brazil. Participants: Eight AB and nine SCI paraplegic. Interventions: Participants underwent three exercise sessions at different relative intensities: at ventilatory threshold 1 intensity (VT1), 15% below VT1, and 15% above VT1. Similar energy expenditures were established from exercises with different intensities for each volunteer. The AB group was tested on a conventional treadmill, whereas the SCI group was tested on a treadmill adapted for wheelchair use. Blood samples were collected at baseline, immediately after, and 30 min after the exercise sessions. Outcome measures: Interleukin 1 receptor antagonist, interleukin 1 beta, interleukin 2, interleukin 4, interleukin 6, interleukin 10 and tumoral necrosis factor alpha were measured. Results: When groups were compared, interleukin–2 was found higher, whereas interleukin–4 and interleukin–10 were found lower in the SCI group at all collection times in the three exercise intensities (all P < 0.05). Interleukin–1 receptor antagonist was found higher immediately after exercise at VT1, 15% above VT1 and 30 min after 15% below VT1 in the AB group (all P < 0.05). In the AB group, an increase in interleukin–6 immediately after the exercise at VT1 compared with baseline was found (P = 0.01). Conclusion: Individuals with SCI may have to perform physical exercise at a higher volume or energy expenditure than AB individuals to obtain similar anti-inflammatory benefits of acute exercise. Trial registration: Uniform Trial Number identifier: U1111-1232-8142. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T01:21:13Z 2020-12-12T01:21:13Z 2020-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1080/10790268.2020.1752976 Journal of Spinal Cord Medicine. 2045-7723 1079-0268 http://hdl.handle.net/11449/198758 10.1080/10790268.2020.1752976 2-s2.0-85083678603 |
url |
http://dx.doi.org/10.1080/10790268.2020.1752976 http://hdl.handle.net/11449/198758 |
identifier_str_mv |
Journal of Spinal Cord Medicine. 2045-7723 1079-0268 10.1080/10790268.2020.1752976 2-s2.0-85083678603 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Spinal Cord Medicine |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128409439567872 |