Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate

Detalhes bibliográficos
Autor(a) principal: Honsho, Cristiane Dos Santos
Data de Publicação: 2014
Outros Autores: Cardoso, Karym Christine De Freitas, Quarterone, Carolina, Franco, Leandro Guimarães, Brunelli, Adriana Torrecilhas Jorge, Dias, Fernanda Gosuen Gonçalves, Magalhães, Geórgia Modé
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/0103-8478cr20131428
http://hdl.handle.net/11449/114264
Resumo: The occlusion of the inferior lacrimal punctum limits tear drainage and thus keeps it over the ocular surface, prolongs lubrication and minimizes the need of ocular lubricants. The aim of this study was to evaluate the effectiveness of n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate adhesives in the occlusion of the inferior lacrimal punctum and canaliculi of dogs and their clinical repercussions over 180 days. Eleven dogs, were divided into two groups: occlusion with n-butyl-cyanoacrylate (GB, n=6) and with 2-octyl-cyanoacrylate (GO, n=5). Tear production, blepharospasm, ocular discharge, epiphora and conjunctival hyperemia were analyzed before the procedure and on days (T) 3,7,15, 30, 45, 60, 90, 120, 150 and 180 after the procedure. Tear production of GB was significantly higher at T90 (P=0.0282) than its control. Variations between days showed that T7 (P=0.0069) and T180 (P=0.0207) varied significantly from T0. In the GO group, when treatment was compared to control, T15 (P<0.001) was significantly different from the rest. Variations between days showed that T15 was significantly different than T0 (P=0.0044), T3 (P=0.0234), T60 (P=0.0207) and T90 (P=0.0482). No significant difference was observed between the treatment groups at any given time. It was concluded that both adhesives were effective in occluding lacrimal drainage for long periods and could thus be considered as therapeutic options in treating animals with lacrimal deficiency
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spelling Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylateOclusão temporária do ponto e canalículo lacrimais inferiores de cães com n-butil-cianoacrilato e 2-octil-cianoacrilatobiomaterialceratoconjuntivite secalágrimabiomaterialkeratoconjunctivitis siccatearThe occlusion of the inferior lacrimal punctum limits tear drainage and thus keeps it over the ocular surface, prolongs lubrication and minimizes the need of ocular lubricants. The aim of this study was to evaluate the effectiveness of n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate adhesives in the occlusion of the inferior lacrimal punctum and canaliculi of dogs and their clinical repercussions over 180 days. Eleven dogs, were divided into two groups: occlusion with n-butyl-cyanoacrylate (GB, n=6) and with 2-octyl-cyanoacrylate (GO, n=5). Tear production, blepharospasm, ocular discharge, epiphora and conjunctival hyperemia were analyzed before the procedure and on days (T) 3,7,15, 30, 45, 60, 90, 120, 150 and 180 after the procedure. Tear production of GB was significantly higher at T90 (P=0.0282) than its control. Variations between days showed that T7 (P=0.0069) and T180 (P=0.0207) varied significantly from T0. In the GO group, when treatment was compared to control, T15 (P<0.001) was significantly different from the rest. Variations between days showed that T15 was significantly different than T0 (P=0.0044), T3 (P=0.0234), T60 (P=0.0207) and T90 (P=0.0482). No significant difference was observed between the treatment groups at any given time. It was concluded that both adhesives were effective in occluding lacrimal drainage for long periods and could thus be considered as therapeutic options in treating animals with lacrimal deficiencyA oclusão do ponto lacrimal inferior limita a drenagem da lágrima, mantendo-a sobre a superfície ocular, prolonga a lubrificação e minimiza a posologia de lubrificantes. Objetivou-se, com este estudo, avaliar a efetividade dos adesivos n-butil-cianoacrilato e 2-octil-cianocacrilato, na oclusão do ponto e canalículo lacrimais inferiores de cães e suas repercussões clínicas durante 180 dias. Para tanto, utilizaram-se 11 cães distribuídos em dois grupos: oclusão com n-butil-cianoacrilato (GB, n=6) e com 2-octil-cianoacrilato (GO; n=5). A produção lacrimal foi avaliada previamente ao procedimento e, posteriormente, aos 3, 7, 15, 30, 45, 60, 90, 120, 150 e 180 dias, assim como blefarospasmo, secreção ocular, epífora e hiperemia conjuntival. A produção lacrimal de GB diferiu significativamente de seu controle no momento T90 (P=0,0282). Entre momentos, T7 (p=0,0069) e T180 (P=0,0207), diferiram de T0. Em GO, comparando-se tratamento e controle, T15 (P<0,001) diferiu-se estatisticamente dos demais. Ao se compararem os momentos, verificou-se que T15 diferiu significativamente de T0 (P= 0,0044), T3 (P= 0,0234), T60 (P= 0,0207) e T 90 (P= 0,0482). Não foi observada diferença entre os tratamentos ao longo do tempo. Concluiu-se que ambos os adesivos foram efetivos para a oclusão da drenagem lacrimal por longo período, sendo uma opção factível para animais com deficiência do filme lacrimalFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade de FrancaUniversidade Estadual PaulistaUniversidade Estadual de Santa CruzUNIFRANUniversidade Estadual PaulistaUniversidade Federal de Santa MariaUniversidade de FrancaUniversidade Estadual Paulista (Unesp)Universidade Estadual de Santa Cruz (UESC)UNIFRANHonsho, Cristiane Dos SantosCardoso, Karym Christine De FreitasQuarterone, CarolinaFranco, Leandro GuimarãesBrunelli, Adriana Torrecilhas JorgeDias, Fernanda Gosuen GonçalvesMagalhães, Geórgia Modé2015-02-02T12:39:23Z2015-02-02T12:39:23Z2014-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1615-1621application/pdfhttp://dx.doi.org/10.1590/0103-8478cr20131428Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 9, p. 1615-1621, 2014.0103-8478http://hdl.handle.net/11449/11426410.1590/0103-8478cr20131428S0103-84782014000901615S0103-84782014000901615.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiência Rural0.5250,337info:eu-repo/semantics/openAccess2023-10-08T06:05:46Zoai:repositorio.unesp.br:11449/114264Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-08T06:05:46Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate
Oclusão temporária do ponto e canalículo lacrimais inferiores de cães com n-butil-cianoacrilato e 2-octil-cianoacrilato
title Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate
spellingShingle Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate
Honsho, Cristiane Dos Santos
biomaterial
ceratoconjuntivite seca
lágrima
biomaterial
keratoconjunctivitis sicca
tear
title_short Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate
title_full Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate
title_fullStr Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate
title_full_unstemmed Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate
title_sort Temporary occlusion of the inferior lacrimal punctum and canaliculi of dogs with n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate
author Honsho, Cristiane Dos Santos
author_facet Honsho, Cristiane Dos Santos
Cardoso, Karym Christine De Freitas
Quarterone, Carolina
Franco, Leandro Guimarães
Brunelli, Adriana Torrecilhas Jorge
Dias, Fernanda Gosuen Gonçalves
Magalhães, Geórgia Modé
author_role author
author2 Cardoso, Karym Christine De Freitas
Quarterone, Carolina
Franco, Leandro Guimarães
Brunelli, Adriana Torrecilhas Jorge
Dias, Fernanda Gosuen Gonçalves
Magalhães, Geórgia Modé
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de Franca
Universidade Estadual Paulista (Unesp)
Universidade Estadual de Santa Cruz (UESC)
UNIFRAN
dc.contributor.author.fl_str_mv Honsho, Cristiane Dos Santos
Cardoso, Karym Christine De Freitas
Quarterone, Carolina
Franco, Leandro Guimarães
Brunelli, Adriana Torrecilhas Jorge
Dias, Fernanda Gosuen Gonçalves
Magalhães, Geórgia Modé
dc.subject.por.fl_str_mv biomaterial
ceratoconjuntivite seca
lágrima
biomaterial
keratoconjunctivitis sicca
tear
topic biomaterial
ceratoconjuntivite seca
lágrima
biomaterial
keratoconjunctivitis sicca
tear
description The occlusion of the inferior lacrimal punctum limits tear drainage and thus keeps it over the ocular surface, prolongs lubrication and minimizes the need of ocular lubricants. The aim of this study was to evaluate the effectiveness of n-butyl-cyanoacrylate and 2-octyl-cyanoacrylate adhesives in the occlusion of the inferior lacrimal punctum and canaliculi of dogs and their clinical repercussions over 180 days. Eleven dogs, were divided into two groups: occlusion with n-butyl-cyanoacrylate (GB, n=6) and with 2-octyl-cyanoacrylate (GO, n=5). Tear production, blepharospasm, ocular discharge, epiphora and conjunctival hyperemia were analyzed before the procedure and on days (T) 3,7,15, 30, 45, 60, 90, 120, 150 and 180 after the procedure. Tear production of GB was significantly higher at T90 (P=0.0282) than its control. Variations between days showed that T7 (P=0.0069) and T180 (P=0.0207) varied significantly from T0. In the GO group, when treatment was compared to control, T15 (P<0.001) was significantly different from the rest. Variations between days showed that T15 was significantly different than T0 (P=0.0044), T3 (P=0.0234), T60 (P=0.0207) and T90 (P=0.0482). No significant difference was observed between the treatment groups at any given time. It was concluded that both adhesives were effective in occluding lacrimal drainage for long periods and could thus be considered as therapeutic options in treating animals with lacrimal deficiency
publishDate 2014
dc.date.none.fl_str_mv 2014-09-01
2015-02-02T12:39:23Z
2015-02-02T12:39:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/0103-8478cr20131428
Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 9, p. 1615-1621, 2014.
0103-8478
http://hdl.handle.net/11449/114264
10.1590/0103-8478cr20131428
S0103-84782014000901615
S0103-84782014000901615.pdf
url http://dx.doi.org/10.1590/0103-8478cr20131428
http://hdl.handle.net/11449/114264
identifier_str_mv Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 9, p. 1615-1621, 2014.
0103-8478
10.1590/0103-8478cr20131428
S0103-84782014000901615
S0103-84782014000901615.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ciência Rural
0.525
0,337
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1615-1621
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799964482008514560

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