Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature

Detalhes bibliográficos
Autor(a) principal: Chang, Claudia Veiga [UNESP]
Data de Publicação: 2008
Outros Autores: Nunes, Vânia dos Santos [UNESP], Felicio, Andre Carvalho, Zanini, Marco Antonio [UNESP], Cunha-Neto, Malebranche B. C., De Castro, Ana Valeria Barros [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0004-27302008000900015
http://hdl.handle.net/11449/70694
Resumo: Craniopharyngiomas and germ cell tumors (GCT) may affect the pituitary-hypothalamic region during childhood. Although different in origin, their clinical and radiological features may be similar. In this article we present a 5-year-old girl with clinical and radiological findings (computer tomography calcification) that were initially considered as craniopharyngioma. However clinical outcome, blood and cerebral spinal fluid tumoral markers, and results from anatomopathology and immunohistochemistry disclosed a mixed GCT. This case report highlights that some clinical features and radiological findings of pituitary-hypothalamic tumors may be misdiagnosed as craniopharyngioma mainly when there is a mature teratoma with cartilaginous tissue differentiation. Copyright© ABE&M.
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spelling Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literatureCraniopharyngiomaGerm cell tumorHypothalamusPituitarycase reportcraniopharyngiomadifferential diagnosisfemalehumanhypophysis tumorhypothalamus tumorneoplasmpathologypreschool childradiographyteratomaChild, PreschoolDiagnosis, DifferentialFemaleHumansHypothalamic NeoplasmsNeoplasms, Germ Cell and EmbryonalPituitary NeoplasmsTeratomaCraniopharyngiomas and germ cell tumors (GCT) may affect the pituitary-hypothalamic region during childhood. Although different in origin, their clinical and radiological features may be similar. In this article we present a 5-year-old girl with clinical and radiological findings (computer tomography calcification) that were initially considered as craniopharyngioma. However clinical outcome, blood and cerebral spinal fluid tumoral markers, and results from anatomopathology and immunohistochemistry disclosed a mixed GCT. This case report highlights that some clinical features and radiological findings of pituitary-hypothalamic tumors may be misdiagnosed as craniopharyngioma mainly when there is a mature teratoma with cartilaginous tissue differentiation. Copyright© ABE&M.Faculdade de Medicina de Botucatu (Unesp), Botucatu, SPDepartamento de Neurologia Universidade Federal de São Paulo (Unifesp), São Paulo, SPUnidade de Neuroendocrinologia Divisão de Neurocirurgia Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Av. Bosque da Saúde, 834/193, Saúde, 04142-081 São Paulo SPFaculdade de Medicina de Botucatu (Unesp), Botucatu, SPUniversidade Estadual Paulista (Unesp)Universidade Federal de São Paulo (UNIFESP)Universidade de São Paulo (USP)Chang, Claudia Veiga [UNESP]Nunes, Vânia dos Santos [UNESP]Felicio, Andre CarvalhoZanini, Marco Antonio [UNESP]Cunha-Neto, Malebranche B. C.De Castro, Ana Valeria Barros [UNESP]2014-05-27T11:23:43Z2014-05-27T11:23:43Z2008-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1501-1504application/pdfhttp://dx.doi.org/10.1590/S0004-27302008000900015Arquivos Brasileiros de Endocrinologia e Metabologia, v. 52, n. 9, p. 1501-1504, 2008.0004-27301677-9487http://hdl.handle.net/11449/7069410.1590/S0004-27302008000900015S0004-273020080009000152-s2.0-601491121022-s2.0-60149112102.pdf2894975141895189Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArquivos Brasileiros de Endocrinologia & Metabologia1.515info:eu-repo/semantics/openAccess2024-08-16T15:45:12Zoai:repositorio.unesp.br:11449/70694Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T15:45:12Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature
title Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature
spellingShingle Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature
Chang, Claudia Veiga [UNESP]
Craniopharyngioma
Germ cell tumor
Hypothalamus
Pituitary
case report
craniopharyngioma
differential diagnosis
female
human
hypophysis tumor
hypothalamus tumor
neoplasm
pathology
preschool child
radiography
teratoma
Child, Preschool
Diagnosis, Differential
Female
Humans
Hypothalamic Neoplasms
Neoplasms, Germ Cell and Embryonal
Pituitary Neoplasms
Teratoma
title_short Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature
title_full Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature
title_fullStr Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature
title_full_unstemmed Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature
title_sort Mixed germ cell tumor of the pituitary-hypothalamic region presenting as craniopharyngioma: Case report and review of the literature
author Chang, Claudia Veiga [UNESP]
author_facet Chang, Claudia Veiga [UNESP]
Nunes, Vânia dos Santos [UNESP]
Felicio, Andre Carvalho
Zanini, Marco Antonio [UNESP]
Cunha-Neto, Malebranche B. C.
De Castro, Ana Valeria Barros [UNESP]
author_role author
author2 Nunes, Vânia dos Santos [UNESP]
Felicio, Andre Carvalho
Zanini, Marco Antonio [UNESP]
Cunha-Neto, Malebranche B. C.
De Castro, Ana Valeria Barros [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Chang, Claudia Veiga [UNESP]
Nunes, Vânia dos Santos [UNESP]
Felicio, Andre Carvalho
Zanini, Marco Antonio [UNESP]
Cunha-Neto, Malebranche B. C.
De Castro, Ana Valeria Barros [UNESP]
dc.subject.por.fl_str_mv Craniopharyngioma
Germ cell tumor
Hypothalamus
Pituitary
case report
craniopharyngioma
differential diagnosis
female
human
hypophysis tumor
hypothalamus tumor
neoplasm
pathology
preschool child
radiography
teratoma
Child, Preschool
Diagnosis, Differential
Female
Humans
Hypothalamic Neoplasms
Neoplasms, Germ Cell and Embryonal
Pituitary Neoplasms
Teratoma
topic Craniopharyngioma
Germ cell tumor
Hypothalamus
Pituitary
case report
craniopharyngioma
differential diagnosis
female
human
hypophysis tumor
hypothalamus tumor
neoplasm
pathology
preschool child
radiography
teratoma
Child, Preschool
Diagnosis, Differential
Female
Humans
Hypothalamic Neoplasms
Neoplasms, Germ Cell and Embryonal
Pituitary Neoplasms
Teratoma
description Craniopharyngiomas and germ cell tumors (GCT) may affect the pituitary-hypothalamic region during childhood. Although different in origin, their clinical and radiological features may be similar. In this article we present a 5-year-old girl with clinical and radiological findings (computer tomography calcification) that were initially considered as craniopharyngioma. However clinical outcome, blood and cerebral spinal fluid tumoral markers, and results from anatomopathology and immunohistochemistry disclosed a mixed GCT. This case report highlights that some clinical features and radiological findings of pituitary-hypothalamic tumors may be misdiagnosed as craniopharyngioma mainly when there is a mature teratoma with cartilaginous tissue differentiation. Copyright© ABE&M.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-01
2014-05-27T11:23:43Z
2014-05-27T11:23:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0004-27302008000900015
Arquivos Brasileiros de Endocrinologia e Metabologia, v. 52, n. 9, p. 1501-1504, 2008.
0004-2730
1677-9487
http://hdl.handle.net/11449/70694
10.1590/S0004-27302008000900015
S0004-27302008000900015
2-s2.0-60149112102
2-s2.0-60149112102.pdf
2894975141895189
url http://dx.doi.org/10.1590/S0004-27302008000900015
http://hdl.handle.net/11449/70694
identifier_str_mv Arquivos Brasileiros de Endocrinologia e Metabologia, v. 52, n. 9, p. 1501-1504, 2008.
0004-2730
1677-9487
10.1590/S0004-27302008000900015
S0004-27302008000900015
2-s2.0-60149112102
2-s2.0-60149112102.pdf
2894975141895189
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia
1.515
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1501-1504
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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