Mycobacterium marinum infection: a case report

Detalhes bibliográficos
Autor(a) principal: Sette, Christiane Salgado
Data de Publicação: 2015
Outros Autores: Wachholz, Patrick Alexander [UNESP], Masuda, Paula Yoshiko, Fortes da Costa Figueira, Renata Borges, Oliveira Mattar, Fernanda Rodrigues de, Ura, Deise Godoy
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.jvat.org/content/21/1/7
http://hdl.handle.net/11449/128399
Resumo: The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group.
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spelling Mycobacterium marinum infection: a case reportMycobacterium infectionsMycobacterium marinumCase reportGranulomaThe infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group.Inst Lauro Souza Lima, BR-17034971 Bauru, SP, BrazilUniv Estadual Paulista, UNESP, Botucatu Med Sch, Dept Publ Hlth, BR-18618970 Botucatu, SP, BrazilUniv Estadual Paulista, UNESP, Botucatu Med Sch, Dept Publ Hlth, BR-18618970 Botucatu, SP, BrazilBiomed Central LtdUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Sette, Christiane SalgadoWachholz, Patrick Alexander [UNESP]Masuda, Paula YoshikoFortes da Costa Figueira, Renata BorgesOliveira Mattar, Fernanda Rodrigues deUra, Deise Godoy2015-10-21T13:09:33Z2015-10-21T13:09:33Z2015-03-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article5application/pdfhttp://www.jvat.org/content/21/1/7Journal Of Venomous Animals And Toxins Including Tropical Diseases, v. 21, 5 p., 2015.1678-9199http://hdl.handle.net/11449/12839910.1186/s40409-015-0008-9WOS:000351827200002WOS000351827200002.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal Of Venomous Animals And Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2024-09-03T14:11:48Zoai:repositorio.unesp.br:11449/128399Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T14:11:48Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Mycobacterium marinum infection: a case report
title Mycobacterium marinum infection: a case report
spellingShingle Mycobacterium marinum infection: a case report
Sette, Christiane Salgado
Mycobacterium infections
Mycobacterium marinum
Case report
Granuloma
title_short Mycobacterium marinum infection: a case report
title_full Mycobacterium marinum infection: a case report
title_fullStr Mycobacterium marinum infection: a case report
title_full_unstemmed Mycobacterium marinum infection: a case report
title_sort Mycobacterium marinum infection: a case report
author Sette, Christiane Salgado
author_facet Sette, Christiane Salgado
Wachholz, Patrick Alexander [UNESP]
Masuda, Paula Yoshiko
Fortes da Costa Figueira, Renata Borges
Oliveira Mattar, Fernanda Rodrigues de
Ura, Deise Godoy
author_role author
author2 Wachholz, Patrick Alexander [UNESP]
Masuda, Paula Yoshiko
Fortes da Costa Figueira, Renata Borges
Oliveira Mattar, Fernanda Rodrigues de
Ura, Deise Godoy
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Sette, Christiane Salgado
Wachholz, Patrick Alexander [UNESP]
Masuda, Paula Yoshiko
Fortes da Costa Figueira, Renata Borges
Oliveira Mattar, Fernanda Rodrigues de
Ura, Deise Godoy
dc.subject.por.fl_str_mv Mycobacterium infections
Mycobacterium marinum
Case report
Granuloma
topic Mycobacterium infections
Mycobacterium marinum
Case report
Granuloma
description The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group.
publishDate 2015
dc.date.none.fl_str_mv 2015-10-21T13:09:33Z
2015-10-21T13:09:33Z
2015-03-20
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.jvat.org/content/21/1/7
Journal Of Venomous Animals And Toxins Including Tropical Diseases, v. 21, 5 p., 2015.
1678-9199
http://hdl.handle.net/11449/128399
10.1186/s40409-015-0008-9
WOS:000351827200002
WOS000351827200002.pdf
url http://www.jvat.org/content/21/1/7
http://hdl.handle.net/11449/128399
identifier_str_mv Journal Of Venomous Animals And Toxins Including Tropical Diseases, v. 21, 5 p., 2015.
1678-9199
10.1186/s40409-015-0008-9
WOS:000351827200002
WOS000351827200002.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal Of Venomous Animals And Toxins Including Tropical Diseases
1.782
0,573
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 5
application/pdf
dc.publisher.none.fl_str_mv Biomed Central Ltd
publisher.none.fl_str_mv Biomed Central Ltd
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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