Mycobacterium marinum infection: a case report
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.jvat.org/content/21/1/7 http://hdl.handle.net/11449/128399 |
Resumo: | The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group. |
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Mycobacterium marinum infection: a case reportMycobacterium infectionsMycobacterium marinumCase reportGranulomaThe infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group.Inst Lauro Souza Lima, BR-17034971 Bauru, SP, BrazilUniv Estadual Paulista, UNESP, Botucatu Med Sch, Dept Publ Hlth, BR-18618970 Botucatu, SP, BrazilUniv Estadual Paulista, UNESP, Botucatu Med Sch, Dept Publ Hlth, BR-18618970 Botucatu, SP, BrazilBiomed Central LtdUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Sette, Christiane SalgadoWachholz, Patrick Alexander [UNESP]Masuda, Paula YoshikoFortes da Costa Figueira, Renata BorgesOliveira Mattar, Fernanda Rodrigues deUra, Deise Godoy2015-10-21T13:09:33Z2015-10-21T13:09:33Z2015-03-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article5application/pdfhttp://www.jvat.org/content/21/1/7Journal Of Venomous Animals And Toxins Including Tropical Diseases, v. 21, 5 p., 2015.1678-9199http://hdl.handle.net/11449/12839910.1186/s40409-015-0008-9WOS:000351827200002WOS000351827200002.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal Of Venomous Animals And Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2024-09-03T14:11:48Zoai:repositorio.unesp.br:11449/128399Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T14:11:48Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Mycobacterium marinum infection: a case report |
title |
Mycobacterium marinum infection: a case report |
spellingShingle |
Mycobacterium marinum infection: a case report Sette, Christiane Salgado Mycobacterium infections Mycobacterium marinum Case report Granuloma |
title_short |
Mycobacterium marinum infection: a case report |
title_full |
Mycobacterium marinum infection: a case report |
title_fullStr |
Mycobacterium marinum infection: a case report |
title_full_unstemmed |
Mycobacterium marinum infection: a case report |
title_sort |
Mycobacterium marinum infection: a case report |
author |
Sette, Christiane Salgado |
author_facet |
Sette, Christiane Salgado Wachholz, Patrick Alexander [UNESP] Masuda, Paula Yoshiko Fortes da Costa Figueira, Renata Borges Oliveira Mattar, Fernanda Rodrigues de Ura, Deise Godoy |
author_role |
author |
author2 |
Wachholz, Patrick Alexander [UNESP] Masuda, Paula Yoshiko Fortes da Costa Figueira, Renata Borges Oliveira Mattar, Fernanda Rodrigues de Ura, Deise Godoy |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Sette, Christiane Salgado Wachholz, Patrick Alexander [UNESP] Masuda, Paula Yoshiko Fortes da Costa Figueira, Renata Borges Oliveira Mattar, Fernanda Rodrigues de Ura, Deise Godoy |
dc.subject.por.fl_str_mv |
Mycobacterium infections Mycobacterium marinum Case report Granuloma |
topic |
Mycobacterium infections Mycobacterium marinum Case report Granuloma |
description |
The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-10-21T13:09:33Z 2015-10-21T13:09:33Z 2015-03-20 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.jvat.org/content/21/1/7 Journal Of Venomous Animals And Toxins Including Tropical Diseases, v. 21, 5 p., 2015. 1678-9199 http://hdl.handle.net/11449/128399 10.1186/s40409-015-0008-9 WOS:000351827200002 WOS000351827200002.pdf |
url |
http://www.jvat.org/content/21/1/7 http://hdl.handle.net/11449/128399 |
identifier_str_mv |
Journal Of Venomous Animals And Toxins Including Tropical Diseases, v. 21, 5 p., 2015. 1678-9199 10.1186/s40409-015-0008-9 WOS:000351827200002 WOS000351827200002.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal Of Venomous Animals And Toxins Including Tropical Diseases 1.782 0,573 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
5 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd |
publisher.none.fl_str_mv |
Biomed Central Ltd |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021392643522560 |