A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)

Detalhes bibliográficos
Autor(a) principal: de Souza, Raphael Freitas
Data de Publicação: 2010
Outros Autores: Lima Chaves, Carolina de Andrade [UNESP], Nasser, Mona, Fedorowicz, Zbys
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-77572010000200002
http://hdl.handle.net/11449/16436
Resumo: Introduction: Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which provide open access to full-text articles. This library includes a number of dental journals some of which may include reports of clinical trials in English, Portuguese and/or Spanish. Thus, SciELO could play an important role as a source of evidence for dental healthcare interventions especially if it yields a sizeable number of high quality reports. Objective: The aim of this study was to identify reports of clinical trials by handsearching of dental journals that are accessible through SciELO, and to assess the overall quality of these reports. Material and methods: Electronic versions of six Brazilian dental Journals indexed in SciELO were handsearched at www.scielo.br in September 2008. Reports of clinical trials were identified and classified as controlled clinical trials (CCTs - prospective, experimental studies comparing 2 or more healthcare interventions in human beings) or randomized controlled trials (RCTs - a random allocation method is clearly reported), according to Cochrane eligibility criteria. Criteria to assess methodological quality included: method of randomization, concealment of treatment allocation, blinded outcome assessment, handling of withdrawals and losses and whether an intention-to-treat analysis had been carried out. Results: The search retrieved 33 CCTs and 43 RCTs. A majority of the reports provided no description of either the method of randomization (75.3%) or concealment of the allocation sequence (84.2%). Participants and outcome assessors were reported as blinded in only 31.2% of the reports. Withdrawals and losses were only clearly described in 6.5% of the reports and none mentioned an intention-to-treat analysis or any similar procedure. Conclusions: The results of this study indicate that a substantial number of reports of trials and systematic reviews are available in the dental journals listed in SciELO, and that these could provide valuable evidence for clinical decision making. However, it is clear that the quality of a number of these reports is of some concern and that improvement in the conduct and reporting of these trials could be achieved if authors adhered to internationally accepted guidelines, e. g. the CONSORT statement.
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spelling A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)Clinical trials as topicRandomized controlled trials as topicEvidence-based medicineBiasJournalism, dentalIntroduction: Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which provide open access to full-text articles. This library includes a number of dental journals some of which may include reports of clinical trials in English, Portuguese and/or Spanish. Thus, SciELO could play an important role as a source of evidence for dental healthcare interventions especially if it yields a sizeable number of high quality reports. Objective: The aim of this study was to identify reports of clinical trials by handsearching of dental journals that are accessible through SciELO, and to assess the overall quality of these reports. Material and methods: Electronic versions of six Brazilian dental Journals indexed in SciELO were handsearched at www.scielo.br in September 2008. Reports of clinical trials were identified and classified as controlled clinical trials (CCTs - prospective, experimental studies comparing 2 or more healthcare interventions in human beings) or randomized controlled trials (RCTs - a random allocation method is clearly reported), according to Cochrane eligibility criteria. Criteria to assess methodological quality included: method of randomization, concealment of treatment allocation, blinded outcome assessment, handling of withdrawals and losses and whether an intention-to-treat analysis had been carried out. Results: The search retrieved 33 CCTs and 43 RCTs. A majority of the reports provided no description of either the method of randomization (75.3%) or concealment of the allocation sequence (84.2%). Participants and outcome assessors were reported as blinded in only 31.2% of the reports. Withdrawals and losses were only clearly described in 6.5% of the reports and none mentioned an intention-to-treat analysis or any similar procedure. Conclusions: The results of this study indicate that a substantial number of reports of trials and systematic reviews are available in the dental journals listed in SciELO, and that these could provide valuable evidence for clinical decision making. However, it is clear that the quality of a number of these reports is of some concern and that improvement in the conduct and reporting of these trials could be achieved if authors adhered to internationally accepted guidelines, e. g. the CONSORT statement.Univ São Paulo, Fac Odontol Ribeirao Preto, Ribeirao Preto Dent Sch, Dept Dent Mat & Prosthodont, BR-14040050 Ribeirao Preto, SP, BrazilSão Paulo State Univ, Araraquara Dent Sch, Dept Dent Mat & Prosthodont, Araraquara, SP, BrazilInst Qual & Efficiency Hlth Care, Dept Hlth Informat, Cologne, GermanyCochrane Collaborat, UK Cochrane Ctr, Bahrain Branch, Awali, BahrainSão Paulo State Univ, Araraquara Dent Sch, Dept Dent Mat & Prosthodont, Araraquara, SP, BrazilUniversidade de São Paulo (USP), Faculdade de Odontologia de BauruUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Inst Qual & Efficiency Hlth CareCochrane Collaboratde Souza, Raphael FreitasLima Chaves, Carolina de Andrade [UNESP]Nasser, MonaFedorowicz, Zbys2014-05-20T13:46:26Z2014-05-20T13:46:26Z2010-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article104-109application/pdfhttp://dx.doi.org/10.1590/S1678-77572010000200002Journal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 18, n. 2, p. 104-109, 2010.1678-7757http://hdl.handle.net/11449/16436S1678-77572010000200002WOS:000277832000002S1678-77572010000200002.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Science1.7090,645info:eu-repo/semantics/openAccess2024-09-27T14:56:20Zoai:repositorio.unesp.br:11449/16436Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-27T14:56:20Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)
title A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)
spellingShingle A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)
de Souza, Raphael Freitas
Clinical trials as topic
Randomized controlled trials as topic
Evidence-based medicine
Bias
Journalism, dental
title_short A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)
title_full A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)
title_fullStr A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)
title_full_unstemmed A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)
title_sort A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)
author de Souza, Raphael Freitas
author_facet de Souza, Raphael Freitas
Lima Chaves, Carolina de Andrade [UNESP]
Nasser, Mona
Fedorowicz, Zbys
author_role author
author2 Lima Chaves, Carolina de Andrade [UNESP]
Nasser, Mona
Fedorowicz, Zbys
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (Unesp)
Inst Qual & Efficiency Hlth Care
Cochrane Collaborat
dc.contributor.author.fl_str_mv de Souza, Raphael Freitas
Lima Chaves, Carolina de Andrade [UNESP]
Nasser, Mona
Fedorowicz, Zbys
dc.subject.por.fl_str_mv Clinical trials as topic
Randomized controlled trials as topic
Evidence-based medicine
Bias
Journalism, dental
topic Clinical trials as topic
Randomized controlled trials as topic
Evidence-based medicine
Bias
Journalism, dental
description Introduction: Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which provide open access to full-text articles. This library includes a number of dental journals some of which may include reports of clinical trials in English, Portuguese and/or Spanish. Thus, SciELO could play an important role as a source of evidence for dental healthcare interventions especially if it yields a sizeable number of high quality reports. Objective: The aim of this study was to identify reports of clinical trials by handsearching of dental journals that are accessible through SciELO, and to assess the overall quality of these reports. Material and methods: Electronic versions of six Brazilian dental Journals indexed in SciELO were handsearched at www.scielo.br in September 2008. Reports of clinical trials were identified and classified as controlled clinical trials (CCTs - prospective, experimental studies comparing 2 or more healthcare interventions in human beings) or randomized controlled trials (RCTs - a random allocation method is clearly reported), according to Cochrane eligibility criteria. Criteria to assess methodological quality included: method of randomization, concealment of treatment allocation, blinded outcome assessment, handling of withdrawals and losses and whether an intention-to-treat analysis had been carried out. Results: The search retrieved 33 CCTs and 43 RCTs. A majority of the reports provided no description of either the method of randomization (75.3%) or concealment of the allocation sequence (84.2%). Participants and outcome assessors were reported as blinded in only 31.2% of the reports. Withdrawals and losses were only clearly described in 6.5% of the reports and none mentioned an intention-to-treat analysis or any similar procedure. Conclusions: The results of this study indicate that a substantial number of reports of trials and systematic reviews are available in the dental journals listed in SciELO, and that these could provide valuable evidence for clinical decision making. However, it is clear that the quality of a number of these reports is of some concern and that improvement in the conduct and reporting of these trials could be achieved if authors adhered to internationally accepted guidelines, e. g. the CONSORT statement.
publishDate 2010
dc.date.none.fl_str_mv 2010-03-01
2014-05-20T13:46:26Z
2014-05-20T13:46:26Z
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dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-77572010000200002
Journal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 18, n. 2, p. 104-109, 2010.
1678-7757
http://hdl.handle.net/11449/16436
S1678-77572010000200002
WOS:000277832000002
S1678-77572010000200002.pdf
url http://dx.doi.org/10.1590/S1678-77572010000200002
http://hdl.handle.net/11449/16436
identifier_str_mv Journal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 18, n. 2, p. 104-109, 2010.
1678-7757
S1678-77572010000200002
WOS:000277832000002
S1678-77572010000200002.pdf
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dc.publisher.none.fl_str_mv Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru
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