Maize resistance to witchweed through changes in strigolactone biosynthesis
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1126/science.abq4775 http://hdl.handle.net/11449/246598 |
Resumo: | Maize (Zea mays) is a major staple crop in Africa, where its yield and the livelihood of millions are compromised by the parasitic witchweed Striga. Germination of Striga is induced by strigolactones exuded from maize roots into the rhizosphere. In a maize germplasm collection, we identified two strigolactones, zealactol and zealactonoic acid, which stimulate less Striga germination than the major maize strigolactone, zealactone. We then showed that a single cytochrome P450, ZmCYP706C37, catalyzes a series of oxidative steps in the maize-strigolactone biosynthetic pathway. Reduction in activity of this enzyme and two others involved in the pathway, ZmMAX1b and ZmCLAMT1, can change strigolactone composition and reduce Striga germination and infection. These results offer prospects for breeding Striga-resistant maize. |
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Maize resistance to witchweed through changes in strigolactone biosynthesisMaize (Zea mays) is a major staple crop in Africa, where its yield and the livelihood of millions are compromised by the parasitic witchweed Striga. Germination of Striga is induced by strigolactones exuded from maize roots into the rhizosphere. In a maize germplasm collection, we identified two strigolactones, zealactol and zealactonoic acid, which stimulate less Striga germination than the major maize strigolactone, zealactone. We then showed that a single cytochrome P450, ZmCYP706C37, catalyzes a series of oxidative steps in the maize-strigolactone biosynthetic pathway. Reduction in activity of this enzyme and two others involved in the pathway, ZmMAX1b and ZmCLAMT1, can change strigolactone composition and reduce Striga germination and infection. These results offer prospects for breeding Striga-resistant maize.Plant Hormone Biology Group Swammerdam Institute for Life Sciences University of Amsterdam, Science Park 904Bioinformatics Group Wageningen University & ResearchHorticultural Sciences Department University of FloridaLaboratorium für Organische Chemie Department of Chemistry and Applied Biosciences ETH ZürichSyngenta Crop Protection AG, Schaffhauserstrasse 101Kyoto University iCeMS, Yoshida Ushinomiya-cho, Sakyo-kuDepartment of Economic Plants and Biotechnology Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of SciencesInternational Maize and Wheat Improvement Center (CIMMYT), PO Box 1041-00621Laboratory of Growth Regulators Institute of Experimental Botany The Czech Academy of Sciences Faculty of Science Palacký University, Šlechtitelů 27Plant genomics and transcriptomics group Institute of Biosciences Sao Paulo State UniversitySection of Cell and Developmental Biology University of California, La JollaSeeds Research Syngenta Crop Protection LLCInternational Institute of Tropical Agriculture, PMB 5320 Oyo RoadPlant genomics and transcriptomics group Institute of Biosciences Sao Paulo State UniversityUniversity of AmsterdamWageningen University & ResearchUniversity of FloridaETH ZürichSyngenta Crop Protection AGiCeMSChinese Academy of SciencesInternational Maize and Wheat Improvement Center (CIMMYT)Palacký UniversityUniversidade Estadual Paulista (UNESP)University of CaliforniaLLCInternational Institute of Tropical AgricultureLi, C.Dong, L.Durairaj, J.Guan, J. C.Yoshimura, M.Quinodoz, P.Horber, R.Gaus, K.Li, J.Setotaw, Y. B.Qi, J.De Groote, H.Wang, Y.Thiombiano, B.Floková, K.Walmsley, A.Charnikhova, T. V.Chojnacka, A.de Lemos, S. Correia [UNESP]Ding, Y.Skibbe, D.Hermann, K.Screpanti, C.De Mesmaeker, A.Schmelz, E. A.Menkir, A.Medema, M.Van Dijk, A. D.J.Wu, J.Koch, K. E.Bouwmeester, H. J.2023-07-29T12:45:17Z2023-07-29T12:45:17Z2023-01-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article94-99http://dx.doi.org/10.1126/science.abq4775Science, v. 379, n. 6627, p. 94-99, 2023.1095-92030036-8075http://hdl.handle.net/11449/24659810.1126/science.abq47752-s2.0-85145645793Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengScienceinfo:eu-repo/semantics/openAccess2023-07-29T12:45:17Zoai:repositorio.unesp.br:11449/246598Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:00:45.795080Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Maize resistance to witchweed through changes in strigolactone biosynthesis |
title |
Maize resistance to witchweed through changes in strigolactone biosynthesis |
spellingShingle |
Maize resistance to witchweed through changes in strigolactone biosynthesis Li, C. |
title_short |
Maize resistance to witchweed through changes in strigolactone biosynthesis |
title_full |
Maize resistance to witchweed through changes in strigolactone biosynthesis |
title_fullStr |
Maize resistance to witchweed through changes in strigolactone biosynthesis |
title_full_unstemmed |
Maize resistance to witchweed through changes in strigolactone biosynthesis |
title_sort |
Maize resistance to witchweed through changes in strigolactone biosynthesis |
author |
Li, C. |
author_facet |
Li, C. Dong, L. Durairaj, J. Guan, J. C. Yoshimura, M. Quinodoz, P. Horber, R. Gaus, K. Li, J. Setotaw, Y. B. Qi, J. De Groote, H. Wang, Y. Thiombiano, B. Floková, K. Walmsley, A. Charnikhova, T. V. Chojnacka, A. de Lemos, S. Correia [UNESP] Ding, Y. Skibbe, D. Hermann, K. Screpanti, C. De Mesmaeker, A. Schmelz, E. A. Menkir, A. Medema, M. Van Dijk, A. D.J. Wu, J. Koch, K. E. Bouwmeester, H. J. |
author_role |
author |
author2 |
Dong, L. Durairaj, J. Guan, J. C. Yoshimura, M. Quinodoz, P. Horber, R. Gaus, K. Li, J. Setotaw, Y. B. Qi, J. De Groote, H. Wang, Y. Thiombiano, B. Floková, K. Walmsley, A. Charnikhova, T. V. Chojnacka, A. de Lemos, S. Correia [UNESP] Ding, Y. Skibbe, D. Hermann, K. Screpanti, C. De Mesmaeker, A. Schmelz, E. A. Menkir, A. Medema, M. Van Dijk, A. D.J. Wu, J. Koch, K. E. Bouwmeester, H. J. |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
University of Amsterdam Wageningen University & Research University of Florida ETH Zürich Syngenta Crop Protection AG iCeMS Chinese Academy of Sciences International Maize and Wheat Improvement Center (CIMMYT) Palacký University Universidade Estadual Paulista (UNESP) University of California LLC International Institute of Tropical Agriculture |
dc.contributor.author.fl_str_mv |
Li, C. Dong, L. Durairaj, J. Guan, J. C. Yoshimura, M. Quinodoz, P. Horber, R. Gaus, K. Li, J. Setotaw, Y. B. Qi, J. De Groote, H. Wang, Y. Thiombiano, B. Floková, K. Walmsley, A. Charnikhova, T. V. Chojnacka, A. de Lemos, S. Correia [UNESP] Ding, Y. Skibbe, D. Hermann, K. Screpanti, C. De Mesmaeker, A. Schmelz, E. A. Menkir, A. Medema, M. Van Dijk, A. D.J. Wu, J. Koch, K. E. Bouwmeester, H. J. |
description |
Maize (Zea mays) is a major staple crop in Africa, where its yield and the livelihood of millions are compromised by the parasitic witchweed Striga. Germination of Striga is induced by strigolactones exuded from maize roots into the rhizosphere. In a maize germplasm collection, we identified two strigolactones, zealactol and zealactonoic acid, which stimulate less Striga germination than the major maize strigolactone, zealactone. We then showed that a single cytochrome P450, ZmCYP706C37, catalyzes a series of oxidative steps in the maize-strigolactone biosynthetic pathway. Reduction in activity of this enzyme and two others involved in the pathway, ZmMAX1b and ZmCLAMT1, can change strigolactone composition and reduce Striga germination and infection. These results offer prospects for breeding Striga-resistant maize. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T12:45:17Z 2023-07-29T12:45:17Z 2023-01-06 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1126/science.abq4775 Science, v. 379, n. 6627, p. 94-99, 2023. 1095-9203 0036-8075 http://hdl.handle.net/11449/246598 10.1126/science.abq4775 2-s2.0-85145645793 |
url |
http://dx.doi.org/10.1126/science.abq4775 http://hdl.handle.net/11449/246598 |
identifier_str_mv |
Science, v. 379, n. 6627, p. 94-99, 2023. 1095-9203 0036-8075 10.1126/science.abq4775 2-s2.0-85145645793 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
94-99 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128593664933888 |