Nutritional, immunological and microbiological profiles of burn patients
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1678-91992009000400014 http://hdl.handle.net/11449/11853 |
Resumo: | A burn is a lesion on an organic tissue resultant from direct or indirect action of heat on the organism. The present study aimed to evaluate the nutritional, immunological and microbiological status of burn patients at the Bauru State Hospital, São Paulo state, Brazil, in 2007. Eight patients, aged more than 18 years and injured up to 24 hours, were evaluated at the moment of hospitalization and seven days later. All victims were males with a mean age of 38 years. on average, 17.5% of their body surfaces were burned and 50% of the patients were eutrophic. There were significant alterations in levels of erythrocytes, hemoglobin, hematocrit, total protein and albumin due to increased endothelial permeability, direct destruction of proteins in the heat-affected area and blood loss from lesions or debridement. At a second moment, cytokines IL-6 and TNF-alpha had augmented significantly, with IL-6 presenting elevated levels in relation to controls at the first moment. Microbiological analysis showed that 100% of the samples collected at hospital admission were negative and after one week Staphylococcus aureus was found in all cultures. Therefore, a burn patient may be considered immunosuppressed and these results indicate significant nutritional, immunological and microbiological alterations that can interfere in his recovery. |
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Nutritional, immunological and microbiological profiles of burn patientsburnnutritioninfectionTNF-alphaIL-6laboratory examsA burn is a lesion on an organic tissue resultant from direct or indirect action of heat on the organism. The present study aimed to evaluate the nutritional, immunological and microbiological status of burn patients at the Bauru State Hospital, São Paulo state, Brazil, in 2007. Eight patients, aged more than 18 years and injured up to 24 hours, were evaluated at the moment of hospitalization and seven days later. All victims were males with a mean age of 38 years. on average, 17.5% of their body surfaces were burned and 50% of the patients were eutrophic. There were significant alterations in levels of erythrocytes, hemoglobin, hematocrit, total protein and albumin due to increased endothelial permeability, direct destruction of proteins in the heat-affected area and blood loss from lesions or debridement. At a second moment, cytokines IL-6 and TNF-alpha had augmented significantly, with IL-6 presenting elevated levels in relation to controls at the first moment. Microbiological analysis showed that 100% of the samples collected at hospital admission were negative and after one week Staphylococcus aureus was found in all cultures. Therefore, a burn patient may be considered immunosuppressed and these results indicate significant nutritional, immunological and microbiological alterations that can interfere in his recovery.UNESP, Fac Med Botucatu, Dept Doencas Trop, Botucatu Med Sch, BR-18618000 Botucatu, SP, BrazilUNESP, Fac Med Botucatu, Dept Doencas Trop, Botucatu Med Sch, BR-18618000 Botucatu, SP, BrazilUniversidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP)Universidade Estadual Paulista (Unesp)Barbosa, A. S. A. A.Calvi, Sueli Aparecida [UNESP]Pereira, Paulo Câmara Marques [UNESP]2014-05-20T13:34:32Z2014-05-20T13:34:32Z2009-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article768-777application/pdfhttp://dx.doi.org/10.1590/S1678-91992009000400014Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 15, n. 4, p. 768-777, 2009.1678-9199http://hdl.handle.net/11449/11853S1678-91992009000400014WOS:000272488500013S1678-91992009000400014-en.pdf217945002269905913653204274182040000-0001-5771-8943Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2023-12-21T06:24:16Zoai:repositorio.unesp.br:11449/11853Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-21T06:24:16Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Nutritional, immunological and microbiological profiles of burn patients |
title |
Nutritional, immunological and microbiological profiles of burn patients |
spellingShingle |
Nutritional, immunological and microbiological profiles of burn patients Barbosa, A. S. A. A. burn nutrition infection TNF-alpha IL-6 laboratory exams |
title_short |
Nutritional, immunological and microbiological profiles of burn patients |
title_full |
Nutritional, immunological and microbiological profiles of burn patients |
title_fullStr |
Nutritional, immunological and microbiological profiles of burn patients |
title_full_unstemmed |
Nutritional, immunological and microbiological profiles of burn patients |
title_sort |
Nutritional, immunological and microbiological profiles of burn patients |
author |
Barbosa, A. S. A. A. |
author_facet |
Barbosa, A. S. A. A. Calvi, Sueli Aparecida [UNESP] Pereira, Paulo Câmara Marques [UNESP] |
author_role |
author |
author2 |
Calvi, Sueli Aparecida [UNESP] Pereira, Paulo Câmara Marques [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Barbosa, A. S. A. A. Calvi, Sueli Aparecida [UNESP] Pereira, Paulo Câmara Marques [UNESP] |
dc.subject.por.fl_str_mv |
burn nutrition infection TNF-alpha IL-6 laboratory exams |
topic |
burn nutrition infection TNF-alpha IL-6 laboratory exams |
description |
A burn is a lesion on an organic tissue resultant from direct or indirect action of heat on the organism. The present study aimed to evaluate the nutritional, immunological and microbiological status of burn patients at the Bauru State Hospital, São Paulo state, Brazil, in 2007. Eight patients, aged more than 18 years and injured up to 24 hours, were evaluated at the moment of hospitalization and seven days later. All victims were males with a mean age of 38 years. on average, 17.5% of their body surfaces were burned and 50% of the patients were eutrophic. There were significant alterations in levels of erythrocytes, hemoglobin, hematocrit, total protein and albumin due to increased endothelial permeability, direct destruction of proteins in the heat-affected area and blood loss from lesions or debridement. At a second moment, cytokines IL-6 and TNF-alpha had augmented significantly, with IL-6 presenting elevated levels in relation to controls at the first moment. Microbiological analysis showed that 100% of the samples collected at hospital admission were negative and after one week Staphylococcus aureus was found in all cultures. Therefore, a burn patient may be considered immunosuppressed and these results indicate significant nutritional, immunological and microbiological alterations that can interfere in his recovery. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 2014-05-20T13:34:32Z 2014-05-20T13:34:32Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1678-91992009000400014 Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 15, n. 4, p. 768-777, 2009. 1678-9199 http://hdl.handle.net/11449/11853 S1678-91992009000400014 WOS:000272488500013 S1678-91992009000400014-en.pdf 2179450022699059 1365320427418204 0000-0001-5771-8943 |
url |
http://dx.doi.org/10.1590/S1678-91992009000400014 http://hdl.handle.net/11449/11853 |
identifier_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 15, n. 4, p. 768-777, 2009. 1678-9199 S1678-91992009000400014 WOS:000272488500013 S1678-91992009000400014-en.pdf 2179450022699059 1365320427418204 0000-0001-5771-8943 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases 1.782 0,573 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
768-777 application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP) |
publisher.none.fl_str_mv |
Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP) |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803047050718216192 |