Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1371/JOURNAL.PNTD.0010652 http://hdl.handle.net/11449/247623 |
Resumo: | Background Neurocysticercosis (NC) is one of the major parasitic diseases affecting the central nervous system and is endemic in much of Asia, sub-Saharan Africa, and Latin America. Its epidemiology is difficult to assess, although official registries are available in Brazil, Colombia, Ecuador, and Mexico. Methodology/Principal findings Using official statistics, we assessed trends in NC hospitalization rates during 1998–2019 in Brazil and Ecuador, during 2004–2019 in Mexico, and during 2009–2019 in Colombia. We also assessed the trend in NC mortality in Brazil (1998–2019), the trend in hospitalizations for NC in a Mexican tertiary-level hospital (Instituto Nacional de Neurología y Neurocirugía [INNN]; 1995–2019), and in Mexican primary care ambulatory clinics (1995–2019). Associations between NC hospitalization rates and the human development index (HDI) were also examined. In Brazil, Ecuador, and Mexico, statistically significant decreases in NC hospitalization rates were observed. In Mexico, a significant increase in the age of patients at INNN was observed, suggesting a decreasing incidence of recent infection. Conversely, a significant increase in NC hospitalization rate was observed in Colombia. HDI was not significantly associated with NC hospitalization rates when adjusting for time. Conclusions The downward trends in NC cases in Brazil, Ecuador, and Mexico are encouraging, especially in the context of the PAHO/WHO plan of action to eliminate neglected tropical diseases from the region. On the other hand, in Colombia, the increased NC hospitalization rate is concerning and needs further evaluation so that the authorities can take specific measures. These results should encourage health authorities in other endemic countries to establish a system of official registries to identify where the need for a control program is most urgent. However, it is also important to remember that NC persists, although less frequently in some Latin American countries, and efforts to achieve its control must continue. |
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Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countriesBackground Neurocysticercosis (NC) is one of the major parasitic diseases affecting the central nervous system and is endemic in much of Asia, sub-Saharan Africa, and Latin America. Its epidemiology is difficult to assess, although official registries are available in Brazil, Colombia, Ecuador, and Mexico. Methodology/Principal findings Using official statistics, we assessed trends in NC hospitalization rates during 1998–2019 in Brazil and Ecuador, during 2004–2019 in Mexico, and during 2009–2019 in Colombia. We also assessed the trend in NC mortality in Brazil (1998–2019), the trend in hospitalizations for NC in a Mexican tertiary-level hospital (Instituto Nacional de Neurología y Neurocirugía [INNN]; 1995–2019), and in Mexican primary care ambulatory clinics (1995–2019). Associations between NC hospitalization rates and the human development index (HDI) were also examined. In Brazil, Ecuador, and Mexico, statistically significant decreases in NC hospitalization rates were observed. In Mexico, a significant increase in the age of patients at INNN was observed, suggesting a decreasing incidence of recent infection. Conversely, a significant increase in NC hospitalization rate was observed in Colombia. HDI was not significantly associated with NC hospitalization rates when adjusting for time. Conclusions The downward trends in NC cases in Brazil, Ecuador, and Mexico are encouraging, especially in the context of the PAHO/WHO plan of action to eliminate neglected tropical diseases from the region. On the other hand, in Colombia, the increased NC hospitalization rate is concerning and needs further evaluation so that the authorities can take specific measures. These results should encourage health authorities in other endemic countries to establish a system of official registries to identify where the need for a control program is most urgent. However, it is also important to remember that NC persists, although less frequently in some Latin American countries, and efforts to achieve its control must continue.Instituto Nacional de Neurología y Neurocirugía Manuel Velasco SuarezFacultad de Medicina Universidad Nacional Autónoma de MéxicoDepartment of Neurology Psychology and Psychiatry Botucatu Medical School UNESP – Universidade Estadual PaulistaGrupo de Investigación Biomedicina Faculty of Medicine Fundación Universitaria Autónoma de las Américas, RisaraldaMaster of Clinical Epidemiology and Biostatistics Universidad Científica del SurSchool of Medicine University of CuencaCUNY Institute for Implementation Science in Population Health City University of New YorkDepartamento de Medicina Genómica y Toxicología Ambiental Instituto de Investigaciones Biomédicas Universidad Nacional Autónoma de MéxicoClínica de Neurocisticercosis Instituto Nacional de Neurología Y Neurocirugía Manuel Velasco SuarezDepartment of Neurology Psychology and Psychiatry Botucatu Medical School UNESP – Universidade Estadual PaulistaInstituto Nacional de Neurología y Neurocirugía Manuel Velasco SuarezUniversidad Nacional Autónoma de MéxicoUniversidade Estadual Paulista (UNESP)Fundación Universitaria Autónoma de las AméricasUniversidad Científica del SurUniversity of CuencaCity University of New YorkInstituto Nacional de Neurología Y Neurocirugía Manuel Velasco SuarezRodríguez-Rivas, RobertoFlisser, AnaNorcia, Luiz Fernando [UNESP]Filho, Pedro Tadao Hamamoto [UNESP]Bonilla-Aldana, D. KatterineRodriguez-Morales, Alfonso J.Carpio, ArturoRomo, Matthew L.Fleury, Agnès2023-07-29T13:21:14Z2023-07-29T13:21:14Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1371/JOURNAL.PNTD.0010652PLoS Neglected Tropical Diseases, v. 16, n. 8, 2022.1935-27351935-2727http://hdl.handle.net/11449/24762310.1371/JOURNAL.PNTD.00106522-s2.0-85138128941Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPLoS Neglected Tropical Diseasesinfo:eu-repo/semantics/openAccess2024-08-16T15:45:41Zoai:repositorio.unesp.br:11449/247623Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T15:45:41Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries |
title |
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries |
spellingShingle |
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries Rodríguez-Rivas, Roberto |
title_short |
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries |
title_full |
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries |
title_fullStr |
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries |
title_full_unstemmed |
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries |
title_sort |
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries |
author |
Rodríguez-Rivas, Roberto |
author_facet |
Rodríguez-Rivas, Roberto Flisser, Ana Norcia, Luiz Fernando [UNESP] Filho, Pedro Tadao Hamamoto [UNESP] Bonilla-Aldana, D. Katterine Rodriguez-Morales, Alfonso J. Carpio, Arturo Romo, Matthew L. Fleury, Agnès |
author_role |
author |
author2 |
Flisser, Ana Norcia, Luiz Fernando [UNESP] Filho, Pedro Tadao Hamamoto [UNESP] Bonilla-Aldana, D. Katterine Rodriguez-Morales, Alfonso J. Carpio, Arturo Romo, Matthew L. Fleury, Agnès |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suarez Universidad Nacional Autónoma de México Universidade Estadual Paulista (UNESP) Fundación Universitaria Autónoma de las Américas Universidad Científica del Sur University of Cuenca City University of New York Instituto Nacional de Neurología Y Neurocirugía Manuel Velasco Suarez |
dc.contributor.author.fl_str_mv |
Rodríguez-Rivas, Roberto Flisser, Ana Norcia, Luiz Fernando [UNESP] Filho, Pedro Tadao Hamamoto [UNESP] Bonilla-Aldana, D. Katterine Rodriguez-Morales, Alfonso J. Carpio, Arturo Romo, Matthew L. Fleury, Agnès |
description |
Background Neurocysticercosis (NC) is one of the major parasitic diseases affecting the central nervous system and is endemic in much of Asia, sub-Saharan Africa, and Latin America. Its epidemiology is difficult to assess, although official registries are available in Brazil, Colombia, Ecuador, and Mexico. Methodology/Principal findings Using official statistics, we assessed trends in NC hospitalization rates during 1998–2019 in Brazil and Ecuador, during 2004–2019 in Mexico, and during 2009–2019 in Colombia. We also assessed the trend in NC mortality in Brazil (1998–2019), the trend in hospitalizations for NC in a Mexican tertiary-level hospital (Instituto Nacional de Neurología y Neurocirugía [INNN]; 1995–2019), and in Mexican primary care ambulatory clinics (1995–2019). Associations between NC hospitalization rates and the human development index (HDI) were also examined. In Brazil, Ecuador, and Mexico, statistically significant decreases in NC hospitalization rates were observed. In Mexico, a significant increase in the age of patients at INNN was observed, suggesting a decreasing incidence of recent infection. Conversely, a significant increase in NC hospitalization rate was observed in Colombia. HDI was not significantly associated with NC hospitalization rates when adjusting for time. Conclusions The downward trends in NC cases in Brazil, Ecuador, and Mexico are encouraging, especially in the context of the PAHO/WHO plan of action to eliminate neglected tropical diseases from the region. On the other hand, in Colombia, the increased NC hospitalization rate is concerning and needs further evaluation so that the authorities can take specific measures. These results should encourage health authorities in other endemic countries to establish a system of official registries to identify where the need for a control program is most urgent. However, it is also important to remember that NC persists, although less frequently in some Latin American countries, and efforts to achieve its control must continue. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 2023-07-29T13:21:14Z 2023-07-29T13:21:14Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1371/JOURNAL.PNTD.0010652 PLoS Neglected Tropical Diseases, v. 16, n. 8, 2022. 1935-2735 1935-2727 http://hdl.handle.net/11449/247623 10.1371/JOURNAL.PNTD.0010652 2-s2.0-85138128941 |
url |
http://dx.doi.org/10.1371/JOURNAL.PNTD.0010652 http://hdl.handle.net/11449/247623 |
identifier_str_mv |
PLoS Neglected Tropical Diseases, v. 16, n. 8, 2022. 1935-2735 1935-2727 10.1371/JOURNAL.PNTD.0010652 2-s2.0-85138128941 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
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PLoS Neglected Tropical Diseases |
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openAccess |
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Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
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Universidade Estadual Paulista (UNESP) |
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UNESP |
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UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
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1808128142364114944 |