Clinicopathological analysis of oral mucous autoimmune disease: A 27-year study

• Autor(a) principal: Loschiavo Arisawa, Emilia Angela
• Data de Publicação: 2008
• Outros Autores: Almeida, Janete Dias [UNESP], Carvalho, Yasmin Rodarte [UNESP], Guimaraes Cabral, Luiz Antonio [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://www.medicinaoral.com/pubmed/medoralv13_i2_p94.pdf; http://hdl.handle.net/11449/22620
• topic: autoimmune diseases; lichen planus; pemphigoid; mucous membrane; pemphigus; erythema multiforme

Objectives: The aim of the present study was to analyze the main clinical and histopathological features of autoimmune diseases with oral manifestations such as oral lichen planus (OLP); mucous membrane pemphigoid (MMP); pemphigus vulgaris (PV) and erythema multiforme (EM). Study design: Retrospective review of 5770 files from the Oral Pathology Laboratory of Sao Jose dos Campos Dental School, São Paulo State University (UNESP) comprising a 27- year period from 1974 to 2000.Results: The cases accounted for 64 (1.10%) of 5770 anatomopathological examinations performed over the study period. Among the autoimmune diseases diagnosed, 49 (76.56%) were OLP, 6 (9.37%) were MMP, 5 (7.82%) were em and 4 (6.25%) were PV. Descriptive statistical analysis was used.Conclusion: The initial manifestations of most autoimmune diseases occur in the oral mucosa. An earlier diagnosis and proper therapeutic protocol will delay the dissemination of the lesions, thus greatly contributing to a better prognosis and quality of life of the patient.