Pythiosis

Detalhes bibliográficos
Autor(a) principal: de Moraes Gimenes Bosco, Sandra [UNESP]
Data de Publicação: 2019
Outros Autores: Chechi, Jéssica Luana [UNESP], da Paz, Giselle Souza [UNESP], Krajaejun, Theerapong
Tipo de documento: Capítulo de livro
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/978-981-13-9435-5_1
http://hdl.handle.net/11449/228800
Resumo: Pythiosis is a granulomatous disease that affects subcutaneous, vascular, ocular, and gastrointestinal tissues of many humans and animals. The disease is caused by the fungus-like pathogen Pythium insidiosum, an oomycete found predominantly in tropical and subtropical areas of the world. Pythiosis in animals (horses and dogs) has been more prevalent in the American continent, while the disease in humans has been mostly reported from Thailand. Susceptibility according to age, sex, and breed of the animals is not considered as determinants for infection. Continuous stay in stagnant water with the presence of abundant plant material is the most important factor responsible for the infection, since the disease is acquired in aquatic environment due to the penetration of motile biflagellate zoospores into injured skin. Diagnosis of pythiosis is often difficult, delayed, and time-consuming due to the lack of clinical experience and diagnostic techniques. Treatment of choice is frequently relied upon extensive surgery, which, however, is not always possible due to the great extension of the lesions. Frequently, the disease has a poor prognosis, leading animals to death or euthanasia. In humans, removal of the infected organ or death is the common outcome. Therefore, new diagnosis methodologies and treatment approaches against pythiosis and its etiological agent would be among the most studied fields in the near future.
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spelling PythiosisAnimalHumanOomycetePythiosisPythiosis is a granulomatous disease that affects subcutaneous, vascular, ocular, and gastrointestinal tissues of many humans and animals. The disease is caused by the fungus-like pathogen Pythium insidiosum, an oomycete found predominantly in tropical and subtropical areas of the world. Pythiosis in animals (horses and dogs) has been more prevalent in the American continent, while the disease in humans has been mostly reported from Thailand. Susceptibility according to age, sex, and breed of the animals is not considered as determinants for infection. Continuous stay in stagnant water with the presence of abundant plant material is the most important factor responsible for the infection, since the disease is acquired in aquatic environment due to the penetration of motile biflagellate zoospores into injured skin. Diagnosis of pythiosis is often difficult, delayed, and time-consuming due to the lack of clinical experience and diagnostic techniques. Treatment of choice is frequently relied upon extensive surgery, which, however, is not always possible due to the great extension of the lesions. Frequently, the disease has a poor prognosis, leading animals to death or euthanasia. In humans, removal of the infected organ or death is the common outcome. Therefore, new diagnosis methodologies and treatment approaches against pythiosis and its etiological agent would be among the most studied fields in the near future.Laboratory of Medical Mycology Department of Microbiology and Immunology Institute of Biosciences Universidade Estadual Paulista, UNESP/BotucatuDepartment of Pathology Faculty of Medicine Ramathibodi Hospital Mahidol UniversityLaboratory of Medical Mycology Department of Microbiology and Immunology Institute of Biosciences Universidade Estadual Paulista, UNESP/BotucatuUniversidade Estadual Paulista (UNESP)Mahidol Universityde Moraes Gimenes Bosco, Sandra [UNESP]Chechi, Jéssica Luana [UNESP]da Paz, Giselle Souza [UNESP]Krajaejun, Theerapong2022-04-29T08:28:39Z2022-04-29T08:28:39Z2019-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart3-26http://dx.doi.org/10.1007/978-981-13-9435-5_1Recent Trends in Human and Animal Mycology, p. 3-26.http://hdl.handle.net/11449/22880010.1007/978-981-13-9435-5_12-s2.0-85085444275Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRecent Trends in Human and Animal Mycologyinfo:eu-repo/semantics/openAccess2022-04-29T08:28:39Zoai:repositorio.unesp.br:11449/228800Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:07:51.817412Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Pythiosis
title Pythiosis
spellingShingle Pythiosis
de Moraes Gimenes Bosco, Sandra [UNESP]
Animal
Human
Oomycete
Pythiosis
title_short Pythiosis
title_full Pythiosis
title_fullStr Pythiosis
title_full_unstemmed Pythiosis
title_sort Pythiosis
author de Moraes Gimenes Bosco, Sandra [UNESP]
author_facet de Moraes Gimenes Bosco, Sandra [UNESP]
Chechi, Jéssica Luana [UNESP]
da Paz, Giselle Souza [UNESP]
Krajaejun, Theerapong
author_role author
author2 Chechi, Jéssica Luana [UNESP]
da Paz, Giselle Souza [UNESP]
Krajaejun, Theerapong
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Mahidol University
dc.contributor.author.fl_str_mv de Moraes Gimenes Bosco, Sandra [UNESP]
Chechi, Jéssica Luana [UNESP]
da Paz, Giselle Souza [UNESP]
Krajaejun, Theerapong
dc.subject.por.fl_str_mv Animal
Human
Oomycete
Pythiosis
topic Animal
Human
Oomycete
Pythiosis
description Pythiosis is a granulomatous disease that affects subcutaneous, vascular, ocular, and gastrointestinal tissues of many humans and animals. The disease is caused by the fungus-like pathogen Pythium insidiosum, an oomycete found predominantly in tropical and subtropical areas of the world. Pythiosis in animals (horses and dogs) has been more prevalent in the American continent, while the disease in humans has been mostly reported from Thailand. Susceptibility according to age, sex, and breed of the animals is not considered as determinants for infection. Continuous stay in stagnant water with the presence of abundant plant material is the most important factor responsible for the infection, since the disease is acquired in aquatic environment due to the penetration of motile biflagellate zoospores into injured skin. Diagnosis of pythiosis is often difficult, delayed, and time-consuming due to the lack of clinical experience and diagnostic techniques. Treatment of choice is frequently relied upon extensive surgery, which, however, is not always possible due to the great extension of the lesions. Frequently, the disease has a poor prognosis, leading animals to death or euthanasia. In humans, removal of the infected organ or death is the common outcome. Therefore, new diagnosis methodologies and treatment approaches against pythiosis and its etiological agent would be among the most studied fields in the near future.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
2022-04-29T08:28:39Z
2022-04-29T08:28:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bookPart
format bookPart
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/978-981-13-9435-5_1
Recent Trends in Human and Animal Mycology, p. 3-26.
http://hdl.handle.net/11449/228800
10.1007/978-981-13-9435-5_1
2-s2.0-85085444275
url http://dx.doi.org/10.1007/978-981-13-9435-5_1
http://hdl.handle.net/11449/228800
identifier_str_mv Recent Trends in Human and Animal Mycology, p. 3-26.
10.1007/978-981-13-9435-5_1
2-s2.0-85085444275
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Recent Trends in Human and Animal Mycology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 3-26
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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