Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/1297-9686-46-27 http://hdl.handle.net/11449/112402 |
Resumo: | Background: Iran is an area of particular interest for investigating goat diversity. Archaeological remains indicate early goat domestication (about 10 000 years ago) in the Iranian Zagros Mountains as well as in the high Euphrates valley and southeastern Anatolia. In addition, mitochondrial DNA data of domestic goats and wild ancestors (C. aegagrusor bezoar) suggest a pre-domestication management of wild populations in southern Zagros and central Iranian Plateau. In this study genetic diversity was assessed in seven Iranian native goat breeds, namely Markhoz, Najdi, Taleshi, Khalkhali, Naini, native Abadeh and Turki-Ghashghaei. A total of 317 animals were characterized using 14 microsatellite loci. Two Pakistani goat populations, Pahari and Teddy, were genotyped for comparison.Results: Iranian goats possess a remarkable genetic diversity (average expected heterozygosity of 0.671 across loci, 10.7 alleles per locus) mainly accounted for by the within-breed component (G(ST) = 5.9%). Positive and highly significant F-IS values in the Naini, Turki-Ghashghaei, Abadeh and Markhoz breeds indicate some level of inbreeding in these populations. Multivariate analyses cluster Iranian goats into northern, central and western groups, with the western breeds relatively distinct from the others. Pakistani breeds show some relationship with Iranian populations, even if their position is not consistent across analyses. Gene flow was higher within regions (west, north, central) compared to between regions but particularly low between the western and the other two regions, probably due to the isolating topography of the Zagros mountain range. The Turki-Ghashghaei, Najdi and Abadeh breeds are reared in geographic areas where mtDNA provided evidence of early domestication. These breeds are highly variable, located on basal short branches in the neighbor-joining tree, close to the origin of the principal component analysis plot and, although highly admixed, they are quite distinct from those reared on the western side of the Zagros mountain range.Conclusions: These observations call for further investigation of the nuclear DNA diversity of these breeds within a much wider geographic context to confirm or re-discuss the current hypothesis (based on maternal lineage data) of an almost exclusive contribution of the eastern Anatolian bezoar to the domestic goat gene pool. |
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Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in IranBackground: Iran is an area of particular interest for investigating goat diversity. Archaeological remains indicate early goat domestication (about 10 000 years ago) in the Iranian Zagros Mountains as well as in the high Euphrates valley and southeastern Anatolia. In addition, mitochondrial DNA data of domestic goats and wild ancestors (C. aegagrusor bezoar) suggest a pre-domestication management of wild populations in southern Zagros and central Iranian Plateau. In this study genetic diversity was assessed in seven Iranian native goat breeds, namely Markhoz, Najdi, Taleshi, Khalkhali, Naini, native Abadeh and Turki-Ghashghaei. A total of 317 animals were characterized using 14 microsatellite loci. Two Pakistani goat populations, Pahari and Teddy, were genotyped for comparison.Results: Iranian goats possess a remarkable genetic diversity (average expected heterozygosity of 0.671 across loci, 10.7 alleles per locus) mainly accounted for by the within-breed component (G(ST) = 5.9%). Positive and highly significant F-IS values in the Naini, Turki-Ghashghaei, Abadeh and Markhoz breeds indicate some level of inbreeding in these populations. Multivariate analyses cluster Iranian goats into northern, central and western groups, with the western breeds relatively distinct from the others. Pakistani breeds show some relationship with Iranian populations, even if their position is not consistent across analyses. Gene flow was higher within regions (west, north, central) compared to between regions but particularly low between the western and the other two regions, probably due to the isolating topography of the Zagros mountain range. The Turki-Ghashghaei, Najdi and Abadeh breeds are reared in geographic areas where mtDNA provided evidence of early domestication. These breeds are highly variable, located on basal short branches in the neighbor-joining tree, close to the origin of the principal component analysis plot and, although highly admixed, they are quite distinct from those reared on the western side of the Zagros mountain range.Conclusions: These observations call for further investigation of the nuclear DNA diversity of these breeds within a much wider geographic context to confirm or re-discuss the current hypothesis (based on maternal lineage data) of an almost exclusive contribution of the eastern Anatolian bezoar to the domestic goat gene pool.International Atomic Energy AgencyAgricultural Biotechnology Research Institute of Iran-North branchABRII, North Branch, Rasht 416354115, IranKarakoram Int Univ, Dept Biol Sci, Gilgit, PakistanUniv Tehran, Sch Biol, Tehran 141556455, IranUniv Tehran, Ctr Excellence Phylogeny Living Organisms, Tehran 141556455, IranNorwegian Univ Sci & Technol, Dept Biol, N-7491 Trondheim, NorwayFood & Agr Org United Nat, Anim Prod & Hlth Div, I-00153 Rome, ItalyEcole Polytech Fed Lausanne, Lab Geog Informat Syst, Sch Civil & Environm Engn ENAC, CH-1015 Lausanne, SwitzerlandUniv Cattolica Sacro Cuore, Ist Zootecn & Biodivers & Ancient DNA BioDNA Res, Piacenza, ItalyUniv Estadual Paulista, Dept Apoio, Lab Bioquim & Biol Mol Anim, Aracatuba, BrazilIAEA, Anim Prod & Hlth Sect, A-1400 Vienna, AustriaUniv Estadual Paulista, Dept Apoio, Lab Bioquim & Biol Mol Anim, Aracatuba, BrazilInternational Atomic Energy AgencyD3.10.25Biomed Central Ltd.ABRIIKarakoram Int UnivUniv TehranNorwegian Univ Sci & TechnolFood & Agr Org United NatEcole Polytech Fed LausanneUniv Cattolica Sacro CuoreUniversidade Estadual Paulista (Unesp)IAEAVahidi, Seyed Mohammad FarhadTarang, Ali RezaNaqvi, Arif-un-NisaAnbaran, Mohsen FalahatiBoettcher, PaulJoost, StephaneColli, LiciaGarcia, José Fernando [UNESP]Ajmone-Marsan, Paolo2014-12-03T13:10:41Z2014-12-03T13:10:41Z2014-04-17info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article12application/pdfhttp://dx.doi.org/10.1186/1297-9686-46-27Genetics Selection Evolution. London: Biomed Central Ltd, v. 46, 12 p., 2014.0999-193Xhttp://hdl.handle.net/11449/11240210.1186/1297-9686-46-27WOS:000336933100001WOS000336933100001.pdf9991374083045897Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengGenetics Selection Evolution3.743info:eu-repo/semantics/openAccess2024-09-04T19:16:19Zoai:repositorio.unesp.br:11449/112402Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-04T19:16:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran |
title |
Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran |
spellingShingle |
Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran Vahidi, Seyed Mohammad Farhad |
title_short |
Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran |
title_full |
Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran |
title_fullStr |
Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran |
title_full_unstemmed |
Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran |
title_sort |
Investigation of the genetic diversity of domestic Capra hircus breeds reared within an early goat domestication area in Iran |
author |
Vahidi, Seyed Mohammad Farhad |
author_facet |
Vahidi, Seyed Mohammad Farhad Tarang, Ali Reza Naqvi, Arif-un-Nisa Anbaran, Mohsen Falahati Boettcher, Paul Joost, Stephane Colli, Licia Garcia, José Fernando [UNESP] Ajmone-Marsan, Paolo |
author_role |
author |
author2 |
Tarang, Ali Reza Naqvi, Arif-un-Nisa Anbaran, Mohsen Falahati Boettcher, Paul Joost, Stephane Colli, Licia Garcia, José Fernando [UNESP] Ajmone-Marsan, Paolo |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
ABRII Karakoram Int Univ Univ Tehran Norwegian Univ Sci & Technol Food & Agr Org United Nat Ecole Polytech Fed Lausanne Univ Cattolica Sacro Cuore Universidade Estadual Paulista (Unesp) IAEA |
dc.contributor.author.fl_str_mv |
Vahidi, Seyed Mohammad Farhad Tarang, Ali Reza Naqvi, Arif-un-Nisa Anbaran, Mohsen Falahati Boettcher, Paul Joost, Stephane Colli, Licia Garcia, José Fernando [UNESP] Ajmone-Marsan, Paolo |
description |
Background: Iran is an area of particular interest for investigating goat diversity. Archaeological remains indicate early goat domestication (about 10 000 years ago) in the Iranian Zagros Mountains as well as in the high Euphrates valley and southeastern Anatolia. In addition, mitochondrial DNA data of domestic goats and wild ancestors (C. aegagrusor bezoar) suggest a pre-domestication management of wild populations in southern Zagros and central Iranian Plateau. In this study genetic diversity was assessed in seven Iranian native goat breeds, namely Markhoz, Najdi, Taleshi, Khalkhali, Naini, native Abadeh and Turki-Ghashghaei. A total of 317 animals were characterized using 14 microsatellite loci. Two Pakistani goat populations, Pahari and Teddy, were genotyped for comparison.Results: Iranian goats possess a remarkable genetic diversity (average expected heterozygosity of 0.671 across loci, 10.7 alleles per locus) mainly accounted for by the within-breed component (G(ST) = 5.9%). Positive and highly significant F-IS values in the Naini, Turki-Ghashghaei, Abadeh and Markhoz breeds indicate some level of inbreeding in these populations. Multivariate analyses cluster Iranian goats into northern, central and western groups, with the western breeds relatively distinct from the others. Pakistani breeds show some relationship with Iranian populations, even if their position is not consistent across analyses. Gene flow was higher within regions (west, north, central) compared to between regions but particularly low between the western and the other two regions, probably due to the isolating topography of the Zagros mountain range. The Turki-Ghashghaei, Najdi and Abadeh breeds are reared in geographic areas where mtDNA provided evidence of early domestication. These breeds are highly variable, located on basal short branches in the neighbor-joining tree, close to the origin of the principal component analysis plot and, although highly admixed, they are quite distinct from those reared on the western side of the Zagros mountain range.Conclusions: These observations call for further investigation of the nuclear DNA diversity of these breeds within a much wider geographic context to confirm or re-discuss the current hypothesis (based on maternal lineage data) of an almost exclusive contribution of the eastern Anatolian bezoar to the domestic goat gene pool. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-03T13:10:41Z 2014-12-03T13:10:41Z 2014-04-17 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/1297-9686-46-27 Genetics Selection Evolution. London: Biomed Central Ltd, v. 46, 12 p., 2014. 0999-193X http://hdl.handle.net/11449/112402 10.1186/1297-9686-46-27 WOS:000336933100001 WOS000336933100001.pdf 9991374083045897 |
url |
http://dx.doi.org/10.1186/1297-9686-46-27 http://hdl.handle.net/11449/112402 |
identifier_str_mv |
Genetics Selection Evolution. London: Biomed Central Ltd, v. 46, 12 p., 2014. 0999-193X 10.1186/1297-9686-46-27 WOS:000336933100001 WOS000336933100001.pdf 9991374083045897 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Genetics Selection Evolution 3.743 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
12 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd. |
publisher.none.fl_str_mv |
Biomed Central Ltd. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021424767696896 |