Melanin as an active layer in biosensors

Detalhes bibliográficos
Autor(a) principal: Silva, Marina Piacenti da [UNESP]
Data de Publicação: 2014
Outros Autores: Fernandes, Jessica Colnaghi, Figueiredo, Natalia Biziak de, Congiu, Mirko [UNESP], Mulato, Marcelo, Oliveira Graeff, Carlos Frederico de [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1063/1.4869638
http://hdl.handle.net/11449/113515
Resumo: The development of pH sensors is of great interest due to its extensive application in several areas such as industrial processes, biochemistry and particularly medical diagnostics. In this study, the pH sensing properties of an extended gate field effect transistor (EGFET) based on melanin thin films as active layer are investigated and the physical mechanisms related to the device operation are discussed. Thin films were produced from different melanin precursors on indium tin oxide (ITO) and gold substrates and were investigated by Atomic Force Microscopy and Electrochemical Impedance Spectroscopy. Experiments were performed in the pH range from 2 to 12. EGFETs with melanin deposited on ITO and on gold substrates showed sensitivities ranging from 31.3 mV/pH to 48.9 mV/pH, depending on the melanin precursor and the substrate used. The pH detection is associated with specific binding sites in its structure, hydroxyl groups and quinone imine. (C) 2014 Author(s).
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spelling Melanin as an active layer in biosensorsThe development of pH sensors is of great interest due to its extensive application in several areas such as industrial processes, biochemistry and particularly medical diagnostics. In this study, the pH sensing properties of an extended gate field effect transistor (EGFET) based on melanin thin films as active layer are investigated and the physical mechanisms related to the device operation are discussed. Thin films were produced from different melanin precursors on indium tin oxide (ITO) and gold substrates and were investigated by Atomic Force Microscopy and Electrochemical Impedance Spectroscopy. Experiments were performed in the pH range from 2 to 12. EGFETs with melanin deposited on ITO and on gold substrates showed sensitivities ranging from 31.3 mV/pH to 48.9 mV/pH, depending on the melanin precursor and the substrate used. The pH detection is associated with specific binding sites in its structure, hydroxyl groups and quinone imine. (C) 2014 Author(s).Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)UNESP, Fac Sci, Dept Phys, Bauru, SP, BrazilUniv Sao Paulo, Dept Phys, Fac Philosophy Sci & Letters Ribeirao Preto, Ribeirao Preto, SP, BrazilUNESP, Fac Sci, Dept Phys, Bauru, SP, BrazilAmerican Institute of Physics (AIP)Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Silva, Marina Piacenti da [UNESP]Fernandes, Jessica ColnaghiFigueiredo, Natalia Biziak deCongiu, Mirko [UNESP]Mulato, MarceloOliveira Graeff, Carlos Frederico de [UNESP]2014-12-03T13:11:45Z2014-12-03T13:11:45Z2014-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article8application/pdfhttp://dx.doi.org/10.1063/1.4869638Aip Advances. Melville: Amer Inst Physics, v. 4, n. 3, 8 p., 2014.2158-3226http://hdl.handle.net/11449/11351510.1063/1.4869638WOS:000334213700064WOS000334213700064.pdf71342365834273080000-0003-0162-8273Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAip Advances1.6530,472info:eu-repo/semantics/openAccess2024-04-25T17:40:19Zoai:repositorio.unesp.br:11449/113515Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:49:57.471548Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Melanin as an active layer in biosensors
title Melanin as an active layer in biosensors
spellingShingle Melanin as an active layer in biosensors
Silva, Marina Piacenti da [UNESP]
title_short Melanin as an active layer in biosensors
title_full Melanin as an active layer in biosensors
title_fullStr Melanin as an active layer in biosensors
title_full_unstemmed Melanin as an active layer in biosensors
title_sort Melanin as an active layer in biosensors
author Silva, Marina Piacenti da [UNESP]
author_facet Silva, Marina Piacenti da [UNESP]
Fernandes, Jessica Colnaghi
Figueiredo, Natalia Biziak de
Congiu, Mirko [UNESP]
Mulato, Marcelo
Oliveira Graeff, Carlos Frederico de [UNESP]
author_role author
author2 Fernandes, Jessica Colnaghi
Figueiredo, Natalia Biziak de
Congiu, Mirko [UNESP]
Mulato, Marcelo
Oliveira Graeff, Carlos Frederico de [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Silva, Marina Piacenti da [UNESP]
Fernandes, Jessica Colnaghi
Figueiredo, Natalia Biziak de
Congiu, Mirko [UNESP]
Mulato, Marcelo
Oliveira Graeff, Carlos Frederico de [UNESP]
description The development of pH sensors is of great interest due to its extensive application in several areas such as industrial processes, biochemistry and particularly medical diagnostics. In this study, the pH sensing properties of an extended gate field effect transistor (EGFET) based on melanin thin films as active layer are investigated and the physical mechanisms related to the device operation are discussed. Thin films were produced from different melanin precursors on indium tin oxide (ITO) and gold substrates and were investigated by Atomic Force Microscopy and Electrochemical Impedance Spectroscopy. Experiments were performed in the pH range from 2 to 12. EGFETs with melanin deposited on ITO and on gold substrates showed sensitivities ranging from 31.3 mV/pH to 48.9 mV/pH, depending on the melanin precursor and the substrate used. The pH detection is associated with specific binding sites in its structure, hydroxyl groups and quinone imine. (C) 2014 Author(s).
publishDate 2014
dc.date.none.fl_str_mv 2014-12-03T13:11:45Z
2014-12-03T13:11:45Z
2014-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1063/1.4869638
Aip Advances. Melville: Amer Inst Physics, v. 4, n. 3, 8 p., 2014.
2158-3226
http://hdl.handle.net/11449/113515
10.1063/1.4869638
WOS:000334213700064
WOS000334213700064.pdf
7134236583427308
0000-0003-0162-8273
url http://dx.doi.org/10.1063/1.4869638
http://hdl.handle.net/11449/113515
identifier_str_mv Aip Advances. Melville: Amer Inst Physics, v. 4, n. 3, 8 p., 2014.
2158-3226
10.1063/1.4869638
WOS:000334213700064
WOS000334213700064.pdf
7134236583427308
0000-0003-0162-8273
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Aip Advances
1.653
0,472
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 8
application/pdf
dc.publisher.none.fl_str_mv American Institute of Physics (AIP)
publisher.none.fl_str_mv American Institute of Physics (AIP)
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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