Melanin as an active layer in biosensors
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1063/1.4869638 http://hdl.handle.net/11449/113515 |
Resumo: | The development of pH sensors is of great interest due to its extensive application in several areas such as industrial processes, biochemistry and particularly medical diagnostics. In this study, the pH sensing properties of an extended gate field effect transistor (EGFET) based on melanin thin films as active layer are investigated and the physical mechanisms related to the device operation are discussed. Thin films were produced from different melanin precursors on indium tin oxide (ITO) and gold substrates and were investigated by Atomic Force Microscopy and Electrochemical Impedance Spectroscopy. Experiments were performed in the pH range from 2 to 12. EGFETs with melanin deposited on ITO and on gold substrates showed sensitivities ranging from 31.3 mV/pH to 48.9 mV/pH, depending on the melanin precursor and the substrate used. The pH detection is associated with specific binding sites in its structure, hydroxyl groups and quinone imine. (C) 2014 Author(s). |
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Repositório Institucional da UNESP |
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2946 |
spelling |
Melanin as an active layer in biosensorsThe development of pH sensors is of great interest due to its extensive application in several areas such as industrial processes, biochemistry and particularly medical diagnostics. In this study, the pH sensing properties of an extended gate field effect transistor (EGFET) based on melanin thin films as active layer are investigated and the physical mechanisms related to the device operation are discussed. Thin films were produced from different melanin precursors on indium tin oxide (ITO) and gold substrates and were investigated by Atomic Force Microscopy and Electrochemical Impedance Spectroscopy. Experiments were performed in the pH range from 2 to 12. EGFETs with melanin deposited on ITO and on gold substrates showed sensitivities ranging from 31.3 mV/pH to 48.9 mV/pH, depending on the melanin precursor and the substrate used. The pH detection is associated with specific binding sites in its structure, hydroxyl groups and quinone imine. (C) 2014 Author(s).Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)UNESP, Fac Sci, Dept Phys, Bauru, SP, BrazilUniv Sao Paulo, Dept Phys, Fac Philosophy Sci & Letters Ribeirao Preto, Ribeirao Preto, SP, BrazilUNESP, Fac Sci, Dept Phys, Bauru, SP, BrazilAmerican Institute of Physics (AIP)Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Silva, Marina Piacenti da [UNESP]Fernandes, Jessica ColnaghiFigueiredo, Natalia Biziak deCongiu, Mirko [UNESP]Mulato, MarceloOliveira Graeff, Carlos Frederico de [UNESP]2014-12-03T13:11:45Z2014-12-03T13:11:45Z2014-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article8application/pdfhttp://dx.doi.org/10.1063/1.4869638Aip Advances. Melville: Amer Inst Physics, v. 4, n. 3, 8 p., 2014.2158-3226http://hdl.handle.net/11449/11351510.1063/1.4869638WOS:000334213700064WOS000334213700064.pdf71342365834273080000-0003-0162-8273Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAip Advances1.6530,472info:eu-repo/semantics/openAccess2024-04-25T17:40:19Zoai:repositorio.unesp.br:11449/113515Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:49:57.471548Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Melanin as an active layer in biosensors |
title |
Melanin as an active layer in biosensors |
spellingShingle |
Melanin as an active layer in biosensors Silva, Marina Piacenti da [UNESP] |
title_short |
Melanin as an active layer in biosensors |
title_full |
Melanin as an active layer in biosensors |
title_fullStr |
Melanin as an active layer in biosensors |
title_full_unstemmed |
Melanin as an active layer in biosensors |
title_sort |
Melanin as an active layer in biosensors |
author |
Silva, Marina Piacenti da [UNESP] |
author_facet |
Silva, Marina Piacenti da [UNESP] Fernandes, Jessica Colnaghi Figueiredo, Natalia Biziak de Congiu, Mirko [UNESP] Mulato, Marcelo Oliveira Graeff, Carlos Frederico de [UNESP] |
author_role |
author |
author2 |
Fernandes, Jessica Colnaghi Figueiredo, Natalia Biziak de Congiu, Mirko [UNESP] Mulato, Marcelo Oliveira Graeff, Carlos Frederico de [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Silva, Marina Piacenti da [UNESP] Fernandes, Jessica Colnaghi Figueiredo, Natalia Biziak de Congiu, Mirko [UNESP] Mulato, Marcelo Oliveira Graeff, Carlos Frederico de [UNESP] |
description |
The development of pH sensors is of great interest due to its extensive application in several areas such as industrial processes, biochemistry and particularly medical diagnostics. In this study, the pH sensing properties of an extended gate field effect transistor (EGFET) based on melanin thin films as active layer are investigated and the physical mechanisms related to the device operation are discussed. Thin films were produced from different melanin precursors on indium tin oxide (ITO) and gold substrates and were investigated by Atomic Force Microscopy and Electrochemical Impedance Spectroscopy. Experiments were performed in the pH range from 2 to 12. EGFETs with melanin deposited on ITO and on gold substrates showed sensitivities ranging from 31.3 mV/pH to 48.9 mV/pH, depending on the melanin precursor and the substrate used. The pH detection is associated with specific binding sites in its structure, hydroxyl groups and quinone imine. (C) 2014 Author(s). |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-03T13:11:45Z 2014-12-03T13:11:45Z 2014-03-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1063/1.4869638 Aip Advances. Melville: Amer Inst Physics, v. 4, n. 3, 8 p., 2014. 2158-3226 http://hdl.handle.net/11449/113515 10.1063/1.4869638 WOS:000334213700064 WOS000334213700064.pdf 7134236583427308 0000-0003-0162-8273 |
url |
http://dx.doi.org/10.1063/1.4869638 http://hdl.handle.net/11449/113515 |
identifier_str_mv |
Aip Advances. Melville: Amer Inst Physics, v. 4, n. 3, 8 p., 2014. 2158-3226 10.1063/1.4869638 WOS:000334213700064 WOS000334213700064.pdf 7134236583427308 0000-0003-0162-8273 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Aip Advances 1.653 0,472 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
8 application/pdf |
dc.publisher.none.fl_str_mv |
American Institute of Physics (AIP) |
publisher.none.fl_str_mv |
American Institute of Physics (AIP) |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129363631144960 |