Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake
Autor(a) principal: | |
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Data de Publicação: | 1994 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/223985 |
Resumo: | Sodium chloride intake was studied in male Holtzman rats weighing 250-300 g submitted to electrolytic and chemical lesion of the cell bodies, not fibers of the amygdaloid complex. Sodium chloride (1.5%) intake increased in animals with electrolytic lesion of the corticomedial nucleus of the amygdala. Sodium chloride (1.5%) intake increased after ibotenic acid injection into the corticomedial nucleus of the amygdala to a larger extent (26.6 ± 9.2 to 147.6 ± 34.6 ml/5 days). The results indicate that sodium intake response can be induced by lesions, which involved only cell bodies. The fibers of passage of the corticomedial nucleus of the amygdala produce a water intake less consistent than that induced by ibotenic acid, which is more acute. The results show that cell bodies of this region of the amygdala are involved in the control of sodium chloride intake. |
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Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intakeamygdalaelectrolytic lesionibotenic acid lesionsodium intakeSodium chloride intake was studied in male Holtzman rats weighing 250-300 g submitted to electrolytic and chemical lesion of the cell bodies, not fibers of the amygdaloid complex. Sodium chloride (1.5%) intake increased in animals with electrolytic lesion of the corticomedial nucleus of the amygdala. Sodium chloride (1.5%) intake increased after ibotenic acid injection into the corticomedial nucleus of the amygdala to a larger extent (26.6 ± 9.2 to 147.6 ± 34.6 ml/5 days). The results indicate that sodium intake response can be induced by lesions, which involved only cell bodies. The fibers of passage of the corticomedial nucleus of the amygdala produce a water intake less consistent than that induced by ibotenic acid, which is more acute. The results show that cell bodies of this region of the amygdala are involved in the control of sodium chloride intake.Dpto. de Ciencias Fisiologicas Faculdade de Odontologia UNESP, Rua Humaita, 1680, 14801-903 Araraquara, SPDpto. de Ciencias Fisiologicas Faculdade de Odontologia UNESP, Rua Humaita, 1680, 14801-903 Araraquara, SPUniversidade Estadual Paulista (UNESP)Saad, W. A. [UNESP]Paulino, M. A. [UNESP]Camargo, L. A.A. [UNESP]Renzi, A. [UNESP]Menani, J. V. [UNESP]Abrao-Saad, W. [UNESP]2022-04-28T19:54:02Z2022-04-28T19:54:02Z1994-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2903-2907Brazilian Journal of Medical and Biological Research, v. 27, n. 12, p. 2903-2907, 1994.0100-879Xhttp://hdl.handle.net/11449/2239852-s2.0-0028576494Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Medical and Biological Researchinfo:eu-repo/semantics/openAccess2022-04-28T19:54:02Zoai:repositorio.unesp.br:11449/223985Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T19:54:02Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake |
title |
Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake |
spellingShingle |
Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake Saad, W. A. [UNESP] amygdala electrolytic lesion ibotenic acid lesion sodium intake |
title_short |
Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake |
title_full |
Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake |
title_fullStr |
Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake |
title_full_unstemmed |
Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake |
title_sort |
Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake |
author |
Saad, W. A. [UNESP] |
author_facet |
Saad, W. A. [UNESP] Paulino, M. A. [UNESP] Camargo, L. A.A. [UNESP] Renzi, A. [UNESP] Menani, J. V. [UNESP] Abrao-Saad, W. [UNESP] |
author_role |
author |
author2 |
Paulino, M. A. [UNESP] Camargo, L. A.A. [UNESP] Renzi, A. [UNESP] Menani, J. V. [UNESP] Abrao-Saad, W. [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Saad, W. A. [UNESP] Paulino, M. A. [UNESP] Camargo, L. A.A. [UNESP] Renzi, A. [UNESP] Menani, J. V. [UNESP] Abrao-Saad, W. [UNESP] |
dc.subject.por.fl_str_mv |
amygdala electrolytic lesion ibotenic acid lesion sodium intake |
topic |
amygdala electrolytic lesion ibotenic acid lesion sodium intake |
description |
Sodium chloride intake was studied in male Holtzman rats weighing 250-300 g submitted to electrolytic and chemical lesion of the cell bodies, not fibers of the amygdaloid complex. Sodium chloride (1.5%) intake increased in animals with electrolytic lesion of the corticomedial nucleus of the amygdala. Sodium chloride (1.5%) intake increased after ibotenic acid injection into the corticomedial nucleus of the amygdala to a larger extent (26.6 ± 9.2 to 147.6 ± 34.6 ml/5 days). The results indicate that sodium intake response can be induced by lesions, which involved only cell bodies. The fibers of passage of the corticomedial nucleus of the amygdala produce a water intake less consistent than that induced by ibotenic acid, which is more acute. The results show that cell bodies of this region of the amygdala are involved in the control of sodium chloride intake. |
publishDate |
1994 |
dc.date.none.fl_str_mv |
1994-12-01 2022-04-28T19:54:02Z 2022-04-28T19:54:02Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Brazilian Journal of Medical and Biological Research, v. 27, n. 12, p. 2903-2907, 1994. 0100-879X http://hdl.handle.net/11449/223985 2-s2.0-0028576494 |
identifier_str_mv |
Brazilian Journal of Medical and Biological Research, v. 27, n. 12, p. 2903-2907, 1994. 0100-879X 2-s2.0-0028576494 |
url |
http://hdl.handle.net/11449/223985 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
2903-2907 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803046148381868032 |