Biological activity of the aqueous extract of Lychnophora pinaster Mart.

Detalhes bibliográficos
Autor(a) principal: Silveira, D.
Data de Publicação: 2005
Outros Autores: Wagner, H., Chiari, E., Lombardi, J.a. [UNESP], Assunção, A.c., Oliveira, A.b. De, Raslan, D.s.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0102-695X2005000400006
http://hdl.handle.net/11449/211391
Resumo: Lyophilized aqueous extract (LAE) from Lychnophora pinaster Mart (Asteraceae) aerial parts was evaluated in the search of possible biological activities. LAE exhibited trypanocidal activity (113.62 mg/mL), but could not inhibit 5-lipoxygenase in vitro (17% of inhibition). LAE chemical characterization by HPLC with UV-Diode Array Detector showed the presence of caffeic acid, isochlorogenic acid, vitexin, isovitexin and quercetin, in comparison with authentic samples.
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spelling Biological activity of the aqueous extract of Lychnophora pinaster Mart.Lychnophora pinastertrypanocidal activity5-lipoxygenase assayLyophilized aqueous extract (LAE) from Lychnophora pinaster Mart (Asteraceae) aerial parts was evaluated in the search of possible biological activities. LAE exhibited trypanocidal activity (113.62 mg/mL), but could not inhibit 5-lipoxygenase in vitro (17% of inhibition). LAE chemical characterization by HPLC with UV-Diode Array Detector showed the presence of caffeic acid, isochlorogenic acid, vitexin, isovitexin and quercetin, in comparison with authentic samples.Universidade Federal de Minas Gerais, Faculdade de FarmáciaUniversidade Estadual Paulista, Departamento de BotânicaUniversidade Federal de Minas Gerais, ICExLM-University of Munich, Institute of PharmacyUniversidade Federal de Minas Gerais, ICBUniversidade de Brasília, Faculdade de Ciências da SaúdeUniversidade Estadual Paulista, Departamento de BotânicaSociedade Brasileira de FarmacognosiaUniversidade Federal de Minas GeraisUniversidade Estadual Paulista (Unesp)LM-University of MunichUniversidade de BrasíliaSilveira, D.Wagner, H.Chiari, E.Lombardi, J.a. [UNESP]Assunção, A.c.Oliveira, A.b. DeRaslan, D.s.2021-07-14T10:23:39Z2021-07-14T10:23:39Z2005-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article294-297application/pdfhttp://dx.doi.org/10.1590/S0102-695X2005000400006Revista Brasileira de Farmacognosia. Curitiba, PR, Brazil: Sociedade Brasileira de Farmacognosia, v. 15, n. 4, p. 294-297, 2005.0102-695X1981-528Xhttp://hdl.handle.net/11449/21139110.1590/S0102-695X2005000400006S0102-695X2005000400006S0102-695X2005000400006.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista Brasileira de Farmacognosiainfo:eu-repo/semantics/openAccess2023-12-07T06:14:11Zoai:repositorio.unesp.br:11449/211391Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:39:46.339426Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Biological activity of the aqueous extract of Lychnophora pinaster Mart.
title Biological activity of the aqueous extract of Lychnophora pinaster Mart.
spellingShingle Biological activity of the aqueous extract of Lychnophora pinaster Mart.
Silveira, D.
Lychnophora pinaster
trypanocidal activity
5-lipoxygenase assay
title_short Biological activity of the aqueous extract of Lychnophora pinaster Mart.
title_full Biological activity of the aqueous extract of Lychnophora pinaster Mart.
title_fullStr Biological activity of the aqueous extract of Lychnophora pinaster Mart.
title_full_unstemmed Biological activity of the aqueous extract of Lychnophora pinaster Mart.
title_sort Biological activity of the aqueous extract of Lychnophora pinaster Mart.
author Silveira, D.
author_facet Silveira, D.
Wagner, H.
Chiari, E.
Lombardi, J.a. [UNESP]
Assunção, A.c.
Oliveira, A.b. De
Raslan, D.s.
author_role author
author2 Wagner, H.
Chiari, E.
Lombardi, J.a. [UNESP]
Assunção, A.c.
Oliveira, A.b. De
Raslan, D.s.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de Minas Gerais
Universidade Estadual Paulista (Unesp)
LM-University of Munich
Universidade de Brasília
dc.contributor.author.fl_str_mv Silveira, D.
Wagner, H.
Chiari, E.
Lombardi, J.a. [UNESP]
Assunção, A.c.
Oliveira, A.b. De
Raslan, D.s.
dc.subject.por.fl_str_mv Lychnophora pinaster
trypanocidal activity
5-lipoxygenase assay
topic Lychnophora pinaster
trypanocidal activity
5-lipoxygenase assay
description Lyophilized aqueous extract (LAE) from Lychnophora pinaster Mart (Asteraceae) aerial parts was evaluated in the search of possible biological activities. LAE exhibited trypanocidal activity (113.62 mg/mL), but could not inhibit 5-lipoxygenase in vitro (17% of inhibition). LAE chemical characterization by HPLC with UV-Diode Array Detector showed the presence of caffeic acid, isochlorogenic acid, vitexin, isovitexin and quercetin, in comparison with authentic samples.
publishDate 2005
dc.date.none.fl_str_mv 2005-12
2021-07-14T10:23:39Z
2021-07-14T10:23:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0102-695X2005000400006
Revista Brasileira de Farmacognosia. Curitiba, PR, Brazil: Sociedade Brasileira de Farmacognosia, v. 15, n. 4, p. 294-297, 2005.
0102-695X
1981-528X
http://hdl.handle.net/11449/211391
10.1590/S0102-695X2005000400006
S0102-695X2005000400006
S0102-695X2005000400006.pdf
url http://dx.doi.org/10.1590/S0102-695X2005000400006
http://hdl.handle.net/11449/211391
identifier_str_mv Revista Brasileira de Farmacognosia. Curitiba, PR, Brazil: Sociedade Brasileira de Farmacognosia, v. 15, n. 4, p. 294-297, 2005.
0102-695X
1981-528X
10.1590/S0102-695X2005000400006
S0102-695X2005000400006
S0102-695X2005000400006.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista Brasileira de Farmacognosia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 294-297
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128231480492032

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