Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals

Detalhes bibliográficos
Autor(a) principal: Rossi, Livia Maria Gonçalves [UNESP]
Data de Publicação: 2014
Outros Autores: Rahal, Paula [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3844/ajidsp.2014.182.186
http://hdl.handle.net/11449/232354
Resumo: Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the field of HCV treatment. Here, we discuss the relevance of identification of HCV resistant mutants from a clinical standpoint. The advantage and limitations of molecular testing in clinical setting is presented.
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spelling Detection of hepatitis C virus resistant mutants in the era of direct acting antiviralsDirect acting-antiviralHepatitis C virusResistant mutantsTherapyHepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the field of HCV treatment. Here, we discuss the relevance of identification of HCV resistant mutants from a clinical standpoint. The advantage and limitations of molecular testing in clinical setting is presented.Department of Biology, Institute of Bioscience, Language and Exact Science, São Paulo State UniversityDepartment of Biology, Institute of Bioscience, Language and Exact Science, São Paulo State UniversityUniversidade Estadual Paulista (UNESP)Rossi, Livia Maria Gonçalves [UNESP]Rahal, Paula [UNESP]2022-04-29T12:27:47Z2022-04-29T12:27:47Z2014-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article182-186http://dx.doi.org/10.3844/ajidsp.2014.182.186American Journal of Infectious Diseases, v. 10, n. 4, p. 182-186, 2014.1553-6203http://hdl.handle.net/11449/23235410.3844/ajidsp.2014.182.1862-s2.0-84920986572Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAmerican Journal of Infectious Diseasesinfo:eu-repo/semantics/openAccess2022-04-29T12:27:47Zoai:repositorio.unesp.br:11449/232354Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:36:12.709164Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
title Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
spellingShingle Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
Rossi, Livia Maria Gonçalves [UNESP]
Direct acting-antiviral
Hepatitis C virus
Resistant mutants
Therapy
title_short Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
title_full Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
title_fullStr Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
title_full_unstemmed Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
title_sort Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
author Rossi, Livia Maria Gonçalves [UNESP]
author_facet Rossi, Livia Maria Gonçalves [UNESP]
Rahal, Paula [UNESP]
author_role author
author2 Rahal, Paula [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Rossi, Livia Maria Gonçalves [UNESP]
Rahal, Paula [UNESP]
dc.subject.por.fl_str_mv Direct acting-antiviral
Hepatitis C virus
Resistant mutants
Therapy
topic Direct acting-antiviral
Hepatitis C virus
Resistant mutants
Therapy
description Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the field of HCV treatment. Here, we discuss the relevance of identification of HCV resistant mutants from a clinical standpoint. The advantage and limitations of molecular testing in clinical setting is presented.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
2022-04-29T12:27:47Z
2022-04-29T12:27:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3844/ajidsp.2014.182.186
American Journal of Infectious Diseases, v. 10, n. 4, p. 182-186, 2014.
1553-6203
http://hdl.handle.net/11449/232354
10.3844/ajidsp.2014.182.186
2-s2.0-84920986572
url http://dx.doi.org/10.3844/ajidsp.2014.182.186
http://hdl.handle.net/11449/232354
identifier_str_mv American Journal of Infectious Diseases, v. 10, n. 4, p. 182-186, 2014.
1553-6203
10.3844/ajidsp.2014.182.186
2-s2.0-84920986572
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv American Journal of Infectious Diseases
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 182-186
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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