Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0103-64402010000500012 http://hdl.handle.net/11449/72082 |
Resumo: | This study proposes a pH-cycling model for verifying the dose-response relationship in fluoride-releasing materials on remineralization in vitro. Sixty bovine enamel blocks were selected for the surface microhardness test (SMH 1). Artificial caries lesions were induced and surface microhardness test (SMH 2) was performed. Forty-eight specimens were prepared with Z 100, Fluroshield, Vitremer and Vitremer 1/4 diluted - powder/liquid, and subjected to a pH-cycling model to promote remineralization. After pH-cycling, final surface microhardness (SMH 3) was assessed to calculate percent recovery of surface microhardness (%SMH R). Fluoride present in enamel (μg F/mm 3) and in the pH-cycling solutions (μg F) was measured. Cross-sectional microhardness was used to calculate mineral content (ΔZ). There was no significant difference between Z 100 and control groups on analysis performed on - %SMH R, ΔZ, μ F and μ F/mm 3 (p>0.05). Results showed a positive correlation between %SMH R and μg F/mm 3 (r=0.9770; p=0.004), %SMH R and μg F (r=0.9939; p=0.0000001), DZ and μg F/mm 3 (r=0.9853; p=0.0002), ΔZ and μg F (r=0.9975; p=0.0000001) and between μg F/mm 3 and μg F (r=0.9819; p=0.001). The pH-cycling model proposed was able to verify in vitro dose-response relationship of fluoride-releasing materials on remineralization. |
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Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling modelDental materialsFluorideTooth remineralizationanticaries agentbiomedical and dental materialsbisphenol A bis(2 hydroxypropyl) ether dimethacrylatefissure sealantfluorideFluoroshieldglass ionomermineralpolyurethanresinsilicon dioxideVitremerZ100 composite resinzirconiumanimalcattlechemistrydental caredental cariesdose responsedrug effectenamelhardnessmethodologypathologypathophysiologypHtooth diseaseAnimalsBisphenol A-Glycidyl MethacrylateCariostatic AgentsCattleComposite ResinsDental CariesDental EnamelDental MaterialsDose-Response Relationship, DrugFluoridesGlass Ionomer CementsHardnessHydrogen-Ion ConcentrationMineralsPit and Fissure SealantsPolyurethanesSilicon DioxideTooth DemineralizationTooth RemineralizationZirconiumThis study proposes a pH-cycling model for verifying the dose-response relationship in fluoride-releasing materials on remineralization in vitro. Sixty bovine enamel blocks were selected for the surface microhardness test (SMH 1). Artificial caries lesions were induced and surface microhardness test (SMH 2) was performed. Forty-eight specimens were prepared with Z 100, Fluroshield, Vitremer and Vitremer 1/4 diluted - powder/liquid, and subjected to a pH-cycling model to promote remineralization. After pH-cycling, final surface microhardness (SMH 3) was assessed to calculate percent recovery of surface microhardness (%SMH R). Fluoride present in enamel (μg F/mm 3) and in the pH-cycling solutions (μg F) was measured. Cross-sectional microhardness was used to calculate mineral content (ΔZ). There was no significant difference between Z 100 and control groups on analysis performed on - %SMH R, ΔZ, μ F and μ F/mm 3 (p>0.05). Results showed a positive correlation between %SMH R and μg F/mm 3 (r=0.9770; p=0.004), %SMH R and μg F (r=0.9939; p=0.0000001), DZ and μg F/mm 3 (r=0.9853; p=0.0002), ΔZ and μg F (r=0.9975; p=0.0000001) and between μg F/mm 3 and μg F (r=0.9819; p=0.001). The pH-cycling model proposed was able to verify in vitro dose-response relationship of fluoride-releasing materials on remineralization.Department of Pediatric and Social Dentistry São Paulo State University, Araçatuba, SPDepartment of Surgery and Integrated Clinic Araçatuba Dental School São Paulo State University, Araçatuba, SPDepartment of Pediatric and Social Dentistry São Paulo State University, Araçatuba, SPDepartment of Surgery and Integrated Clinic Araçatuba Dental School São Paulo State University, Araçatuba, SPUniversidade Estadual Paulista (Unesp)Rodrigues, Eliana [UNESP]Delbem, Alberto Carlos Botazzo [UNESP]Pedrini, Denise [UNESP]Cavassan, Luciana [UNESP]2014-05-27T11:25:22Z2014-05-27T11:25:22Z2010-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article446-451application/pdfhttp://dx.doi.org/10.1590/S0103-64402010000500012Brazilian Dental Journal, v. 21, n. 5, p. 446-451, 2010.0103-64401806-4760http://hdl.handle.net/11449/7208210.1590/S0103-64402010000500012S0103-644020100005000122-s2.0-786507585192-s2.0-78650758519.pdf0000-0002-8159-4853Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Dental Journal0,476info:eu-repo/semantics/openAccess2023-12-24T06:13:54Zoai:repositorio.unesp.br:11449/72082Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-24T06:13:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model |
title |
Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model |
spellingShingle |
Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model Rodrigues, Eliana [UNESP] Dental materials Fluoride Tooth remineralization anticaries agent biomedical and dental materials bisphenol A bis(2 hydroxypropyl) ether dimethacrylate fissure sealant fluoride Fluoroshield glass ionomer mineral polyurethan resin silicon dioxide Vitremer Z100 composite resin zirconium animal cattle chemistry dental care dental caries dose response drug effect enamel hardness methodology pathology pathophysiology pH tooth disease Animals Bisphenol A-Glycidyl Methacrylate Cariostatic Agents Cattle Composite Resins Dental Caries Dental Enamel Dental Materials Dose-Response Relationship, Drug Fluorides Glass Ionomer Cements Hardness Hydrogen-Ion Concentration Minerals Pit and Fissure Sealants Polyurethanes Silicon Dioxide Tooth Demineralization Tooth Remineralization Zirconium |
title_short |
Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model |
title_full |
Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model |
title_fullStr |
Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model |
title_full_unstemmed |
Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model |
title_sort |
Enamel remineralization by fluoride-releasing materials: Proposal of a pH-cycling model |
author |
Rodrigues, Eliana [UNESP] |
author_facet |
Rodrigues, Eliana [UNESP] Delbem, Alberto Carlos Botazzo [UNESP] Pedrini, Denise [UNESP] Cavassan, Luciana [UNESP] |
author_role |
author |
author2 |
Delbem, Alberto Carlos Botazzo [UNESP] Pedrini, Denise [UNESP] Cavassan, Luciana [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Rodrigues, Eliana [UNESP] Delbem, Alberto Carlos Botazzo [UNESP] Pedrini, Denise [UNESP] Cavassan, Luciana [UNESP] |
dc.subject.por.fl_str_mv |
Dental materials Fluoride Tooth remineralization anticaries agent biomedical and dental materials bisphenol A bis(2 hydroxypropyl) ether dimethacrylate fissure sealant fluoride Fluoroshield glass ionomer mineral polyurethan resin silicon dioxide Vitremer Z100 composite resin zirconium animal cattle chemistry dental care dental caries dose response drug effect enamel hardness methodology pathology pathophysiology pH tooth disease Animals Bisphenol A-Glycidyl Methacrylate Cariostatic Agents Cattle Composite Resins Dental Caries Dental Enamel Dental Materials Dose-Response Relationship, Drug Fluorides Glass Ionomer Cements Hardness Hydrogen-Ion Concentration Minerals Pit and Fissure Sealants Polyurethanes Silicon Dioxide Tooth Demineralization Tooth Remineralization Zirconium |
topic |
Dental materials Fluoride Tooth remineralization anticaries agent biomedical and dental materials bisphenol A bis(2 hydroxypropyl) ether dimethacrylate fissure sealant fluoride Fluoroshield glass ionomer mineral polyurethan resin silicon dioxide Vitremer Z100 composite resin zirconium animal cattle chemistry dental care dental caries dose response drug effect enamel hardness methodology pathology pathophysiology pH tooth disease Animals Bisphenol A-Glycidyl Methacrylate Cariostatic Agents Cattle Composite Resins Dental Caries Dental Enamel Dental Materials Dose-Response Relationship, Drug Fluorides Glass Ionomer Cements Hardness Hydrogen-Ion Concentration Minerals Pit and Fissure Sealants Polyurethanes Silicon Dioxide Tooth Demineralization Tooth Remineralization Zirconium |
description |
This study proposes a pH-cycling model for verifying the dose-response relationship in fluoride-releasing materials on remineralization in vitro. Sixty bovine enamel blocks were selected for the surface microhardness test (SMH 1). Artificial caries lesions were induced and surface microhardness test (SMH 2) was performed. Forty-eight specimens were prepared with Z 100, Fluroshield, Vitremer and Vitremer 1/4 diluted - powder/liquid, and subjected to a pH-cycling model to promote remineralization. After pH-cycling, final surface microhardness (SMH 3) was assessed to calculate percent recovery of surface microhardness (%SMH R). Fluoride present in enamel (μg F/mm 3) and in the pH-cycling solutions (μg F) was measured. Cross-sectional microhardness was used to calculate mineral content (ΔZ). There was no significant difference between Z 100 and control groups on analysis performed on - %SMH R, ΔZ, μ F and μ F/mm 3 (p>0.05). Results showed a positive correlation between %SMH R and μg F/mm 3 (r=0.9770; p=0.004), %SMH R and μg F (r=0.9939; p=0.0000001), DZ and μg F/mm 3 (r=0.9853; p=0.0002), ΔZ and μg F (r=0.9975; p=0.0000001) and between μg F/mm 3 and μg F (r=0.9819; p=0.001). The pH-cycling model proposed was able to verify in vitro dose-response relationship of fluoride-releasing materials on remineralization. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-12-01 2014-05-27T11:25:22Z 2014-05-27T11:25:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0103-64402010000500012 Brazilian Dental Journal, v. 21, n. 5, p. 446-451, 2010. 0103-6440 1806-4760 http://hdl.handle.net/11449/72082 10.1590/S0103-64402010000500012 S0103-64402010000500012 2-s2.0-78650758519 2-s2.0-78650758519.pdf 0000-0002-8159-4853 |
url |
http://dx.doi.org/10.1590/S0103-64402010000500012 http://hdl.handle.net/11449/72082 |
identifier_str_mv |
Brazilian Dental Journal, v. 21, n. 5, p. 446-451, 2010. 0103-6440 1806-4760 10.1590/S0103-64402010000500012 S0103-64402010000500012 2-s2.0-78650758519 2-s2.0-78650758519.pdf 0000-0002-8159-4853 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Dental Journal 0,476 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
446-451 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803650068194000896 |