Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.5216/RPT.V49I2.63481 http://hdl.handle.net/11449/221553 |
Resumo: | This study aimed to identify Candida spp. collected from oral mucosa and maintained in culture collections, correlating the findings with the medical history of patients and comparing with data from the literature over the past five years. Seven hundred and eleven oral Candida spp. isolates, collected between 2013 and 2017, were selected and identified using traditional and molecular methods. In addition, a literature review was performed with the key words: Oral, Candida and Yeast. Seven species of the genus Candida: were identified C. albicans (73.3%); C. tropicalis (9.3%); C. parapsilosis (8.2%); C. glabrata (3.9%); C. guilliermondii (2.8%); C. krusei (1.7%) and C. lusitaniae (0.3%). The strains identified as C. albicans were submitted to molecular methods using specific primers and of these, 5.8% were identified as C. dubliniensis strains. The greatest diversity of strains was found in patients presenting no systemic diseases or HIV +, while the highest percentage of strains of Candida non-albicans were observed in cancer patients. This study reports a representative distribution of Candida species among individuals exhibiting distinct clinical conditions, in order to contribute to the design of future research on details of aspects involved in the infections caused by these microorganisms. The correct identification of oral Candida strains contributes to a realistic epidemiological approach and future clinical protocols against these pathogens. |
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Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature reviewCandidaCo-infectionDentistryHIVOral candidiasisYeastsThis study aimed to identify Candida spp. collected from oral mucosa and maintained in culture collections, correlating the findings with the medical history of patients and comparing with data from the literature over the past five years. Seven hundred and eleven oral Candida spp. isolates, collected between 2013 and 2017, were selected and identified using traditional and molecular methods. In addition, a literature review was performed with the key words: Oral, Candida and Yeast. Seven species of the genus Candida: were identified C. albicans (73.3%); C. tropicalis (9.3%); C. parapsilosis (8.2%); C. glabrata (3.9%); C. guilliermondii (2.8%); C. krusei (1.7%) and C. lusitaniae (0.3%). The strains identified as C. albicans were submitted to molecular methods using specific primers and of these, 5.8% were identified as C. dubliniensis strains. The greatest diversity of strains was found in patients presenting no systemic diseases or HIV +, while the highest percentage of strains of Candida non-albicans were observed in cancer patients. This study reports a representative distribution of Candida species among individuals exhibiting distinct clinical conditions, in order to contribute to the design of future research on details of aspects involved in the infections caused by these microorganisms. The correct identification of oral Candida strains contributes to a realistic epidemiological approach and future clinical protocols against these pathogens.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Department of Stomatology School of Dentistry University of São Paulo (USP)Adolfo Lutz Institute Section of Biomedical Sciences Mycology LaboratoryDepartment of Clinical Analysis University of UnicentroDepartment of Microbiology and Immunology University of AlfenasDepartment of Gynecology and Obstetrics Medical School USPInstitute of Biosciences Univ. Estadual PaulistaInstitute of Biosciences Univ. Estadual PaulistaUniversidade de São Paulo (USP)Mycology LaboratoryUniversity of UnicentroUniversity of AlfenasUniversidade Estadual Paulista (UNESP)Dos Santos, Rennan Luiz OliveiraDa Silva Ruiz, LucianaAuler, Marcos ErenoChavasco, Jorge KleberMoreira, DéboraRamos, Regina Teixeira BarbieriLara, Bruna Rossini [UNESP]Paula, Claudete Rodrigues2022-04-28T19:29:20Z2022-04-28T19:29:20Z2020-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article105-119http://dx.doi.org/10.5216/RPT.V49I2.63481Journal of Tropical Pathology, v. 49, n. 2, p. 105-119, 2020.1980-81780301-0406http://hdl.handle.net/11449/22155310.5216/RPT.V49I2.634812-s2.0-85090885709Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Tropical Pathologyinfo:eu-repo/semantics/openAccess2022-04-28T19:29:20Zoai:repositorio.unesp.br:11449/221553Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:05:27.852254Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review |
title |
Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review |
spellingShingle |
Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review Dos Santos, Rennan Luiz Oliveira Candida Co-infection Dentistry HIV Oral candidiasis Yeasts |
title_short |
Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review |
title_full |
Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review |
title_fullStr |
Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review |
title_full_unstemmed |
Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review |
title_sort |
Multicenter study of Candida species in oral mucosa of different patients: Analysis of 711 strains and literature review |
author |
Dos Santos, Rennan Luiz Oliveira |
author_facet |
Dos Santos, Rennan Luiz Oliveira Da Silva Ruiz, Luciana Auler, Marcos Ereno Chavasco, Jorge Kleber Moreira, Débora Ramos, Regina Teixeira Barbieri Lara, Bruna Rossini [UNESP] Paula, Claudete Rodrigues |
author_role |
author |
author2 |
Da Silva Ruiz, Luciana Auler, Marcos Ereno Chavasco, Jorge Kleber Moreira, Débora Ramos, Regina Teixeira Barbieri Lara, Bruna Rossini [UNESP] Paula, Claudete Rodrigues |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Mycology Laboratory University of Unicentro University of Alfenas Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Dos Santos, Rennan Luiz Oliveira Da Silva Ruiz, Luciana Auler, Marcos Ereno Chavasco, Jorge Kleber Moreira, Débora Ramos, Regina Teixeira Barbieri Lara, Bruna Rossini [UNESP] Paula, Claudete Rodrigues |
dc.subject.por.fl_str_mv |
Candida Co-infection Dentistry HIV Oral candidiasis Yeasts |
topic |
Candida Co-infection Dentistry HIV Oral candidiasis Yeasts |
description |
This study aimed to identify Candida spp. collected from oral mucosa and maintained in culture collections, correlating the findings with the medical history of patients and comparing with data from the literature over the past five years. Seven hundred and eleven oral Candida spp. isolates, collected between 2013 and 2017, were selected and identified using traditional and molecular methods. In addition, a literature review was performed with the key words: Oral, Candida and Yeast. Seven species of the genus Candida: were identified C. albicans (73.3%); C. tropicalis (9.3%); C. parapsilosis (8.2%); C. glabrata (3.9%); C. guilliermondii (2.8%); C. krusei (1.7%) and C. lusitaniae (0.3%). The strains identified as C. albicans were submitted to molecular methods using specific primers and of these, 5.8% were identified as C. dubliniensis strains. The greatest diversity of strains was found in patients presenting no systemic diseases or HIV +, while the highest percentage of strains of Candida non-albicans were observed in cancer patients. This study reports a representative distribution of Candida species among individuals exhibiting distinct clinical conditions, in order to contribute to the design of future research on details of aspects involved in the infections caused by these microorganisms. The correct identification of oral Candida strains contributes to a realistic epidemiological approach and future clinical protocols against these pathogens. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-07-01 2022-04-28T19:29:20Z 2022-04-28T19:29:20Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.5216/RPT.V49I2.63481 Journal of Tropical Pathology, v. 49, n. 2, p. 105-119, 2020. 1980-8178 0301-0406 http://hdl.handle.net/11449/221553 10.5216/RPT.V49I2.63481 2-s2.0-85090885709 |
url |
http://dx.doi.org/10.5216/RPT.V49I2.63481 http://hdl.handle.net/11449/221553 |
identifier_str_mv |
Journal of Tropical Pathology, v. 49, n. 2, p. 105-119, 2020. 1980-8178 0301-0406 10.5216/RPT.V49I2.63481 2-s2.0-85090885709 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Tropical Pathology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
105-119 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808129489295638528 |