Effect of the interlamellar anion on CuMgFe-LDH in solar photo-Fenton and Fenton-like degradation of the anticancer drug 5-fluorouracil

• Autor(a) principal: Costa-Serge, Nayara de M. [UNESP]
• Data de Publicação: 2022
• Outros Autores: Lima Gonçalves, Rosembergue G. [UNESP], Ramirez-Ubillus, Manuel A. [UNESP], Li, Chan, Hammer, Peter [UNESP], Chiron, Serge, Pupo Nogueira, Raquel F. [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1016/j.apcatb.2022.121537; http://hdl.handle.net/11449/241896
• topic: Borate anion; Hydroperoxyl/superoxide radical; Hydrotalcite; Singlet oxygen

The influence of the interlamellar anion in Layered Double Hydroxide was investigated for the first time in Fenton-like and solar photo-Fenton processes for the degradation of the anticancer drug 5-fluorouracil (5-FU). LDHs of the MgFeCu type were synthesized by coprecipitation with the insertion of CO32-, NO3-, SO42- and B(OH)4-. A strong effect of the interlamellar anion was observed on the catalytic activity with pseudo-first-order rate constant sequence (k): CuMgFe-B(OH)4 > CuMgFe-NO3 > CuMgFe-SO4 > CuMgFe-CO3. Using CuMgFe-B(OH)4, 5-FU was completely degraded under solar radiation after 20 min and after 40 min in the dark, with degradation efficiency maintained above 90% until the fourth cycle of use. It was found that molecular B-O and B-OH interactions induced modifications of the CuMgFe-B(OH)4 surface charge density, accelerating the reduction of Cu(II) and Fe(III), thus favoring reactive oxygen species generation. This performance denotes the excellent potential of CuMgFe-B(OH)4 for 5-FU degradation.