Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.watres.2010.10.029 http://hdl.handle.net/11449/42589 |
Resumo: | The influence of iron species on amoxicillin (AMX) degradation, intermediate products generated and toxicity during the photo-Fenton process using a solar simulator were evaluated in this work. The AMX degradation was favored in the presence of the potassium ferrioxalate complex (FeOx) when compared to FeSO(4). Total oxidation of AMX in the presence of FeOx was obtained after 5 min, while 15 min were necessary using FeSO4. The results obtained with Daphnia magna biossays showed that the toxicity decreased from 65 to 5% after 90 min of irradiation in the presence of FeSO(4). However, it increased again to a maximum of 100% after 150 min, what indicates the generation of more toxic intermediates than AMX, reaching 45% after 240 min. However, using FeOx, the inhibition of mobility varied between 100 and 70% during treatment, probably due to the presence of oxalate, which is toxic to the neonates. After 240 min, between 73 and 81% TOC removal was observed. Different pathways of AMX degradation were suggested including the opening of the four-membered beta-lactamic ring and further oxidations of the methyl group to aldehyde and/or hydroxylation of the benzoic ring, generating other intermediates after bound cleavage between different atoms and further oxidation to carboxylates such acetate, oxalate and propionate, besides the generation of nitrate and ammonium. (C) 2010 Elsevier Ltd. All rights reserved. |
id |
UNSP_b3658bff886a46c7bca466ec10b16420 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/42589 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessmentPharmaceuticalsWastewaterAdvanced oxidation processesHydrolysisLC-TOF-MSDegradation pathwayThe influence of iron species on amoxicillin (AMX) degradation, intermediate products generated and toxicity during the photo-Fenton process using a solar simulator were evaluated in this work. The AMX degradation was favored in the presence of the potassium ferrioxalate complex (FeOx) when compared to FeSO(4). Total oxidation of AMX in the presence of FeOx was obtained after 5 min, while 15 min were necessary using FeSO4. The results obtained with Daphnia magna biossays showed that the toxicity decreased from 65 to 5% after 90 min of irradiation in the presence of FeSO(4). However, it increased again to a maximum of 100% after 150 min, what indicates the generation of more toxic intermediates than AMX, reaching 45% after 240 min. However, using FeOx, the inhibition of mobility varied between 100 and 70% during treatment, probably due to the presence of oxalate, which is toxic to the neonates. After 240 min, between 73 and 81% TOC removal was observed. Different pathways of AMX degradation were suggested including the opening of the four-membered beta-lactamic ring and further oxidations of the methyl group to aldehyde and/or hydroxylation of the benzoic ring, generating other intermediates after bound cleavage between different atoms and further oxidation to carboxylates such acetate, oxalate and propionate, besides the generation of nitrate and ammonium. (C) 2010 Elsevier Ltd. All rights reserved.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Spanish Ministry of EducationAndalusia Regional GovernmentUNESP Univ Estadual Paulista, Inst Quim Araraquara, BR-14801970 Araraquara, SP, BrazilUniv Almeria, Pesticide Residues Grp, Almeria 04120, SpainCIEMAT, Tabernas 04200, Almeria, SpainUNESP Univ Estadual Paulista, Inst Quim Araraquara, BR-14801970 Araraquara, SP, BrazilSpanish Ministry of Education: CSD2006-00044Andalusia Regional Government: P06-TEP-02329Pergamon-Elsevier B.V. LtdUniversidade Estadual Paulista (Unesp)Univ AlmeriaCIEMATTrovo, Alam G. [UNESP]Pupo Nogueira, Raquel F. [UNESP]Agueera, AnaFernandez-Alba, Amadeo R.Malato, Sixto2014-05-20T15:34:35Z2014-05-20T15:34:35Z2011-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1394-1402application/pdfhttp://dx.doi.org/10.1016/j.watres.2010.10.029Water Research. Oxford: Pergamon-Elsevier B.V. Ltd, v. 45, n. 3, p. 1394-1402, 2011.0043-1354http://hdl.handle.net/11449/4258910.1016/j.watres.2010.10.029WOS:000287054500042WOS000287054500042.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengWater Research7.0512,601info:eu-repo/semantics/openAccess2024-01-22T06:30:00Zoai:repositorio.unesp.br:11449/42589Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:43:29.056195Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment |
title |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment |
spellingShingle |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment Trovo, Alam G. [UNESP] Pharmaceuticals Wastewater Advanced oxidation processes Hydrolysis LC-TOF-MS Degradation pathway |
title_short |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment |
title_full |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment |
title_fullStr |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment |
title_full_unstemmed |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment |
title_sort |
Degradation of the antibiotic amoxicillin by photo-Fenton process - Chemical and toxicological assessment |
author |
Trovo, Alam G. [UNESP] |
author_facet |
Trovo, Alam G. [UNESP] Pupo Nogueira, Raquel F. [UNESP] Agueera, Ana Fernandez-Alba, Amadeo R. Malato, Sixto |
author_role |
author |
author2 |
Pupo Nogueira, Raquel F. [UNESP] Agueera, Ana Fernandez-Alba, Amadeo R. Malato, Sixto |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Univ Almeria CIEMAT |
dc.contributor.author.fl_str_mv |
Trovo, Alam G. [UNESP] Pupo Nogueira, Raquel F. [UNESP] Agueera, Ana Fernandez-Alba, Amadeo R. Malato, Sixto |
dc.subject.por.fl_str_mv |
Pharmaceuticals Wastewater Advanced oxidation processes Hydrolysis LC-TOF-MS Degradation pathway |
topic |
Pharmaceuticals Wastewater Advanced oxidation processes Hydrolysis LC-TOF-MS Degradation pathway |
description |
The influence of iron species on amoxicillin (AMX) degradation, intermediate products generated and toxicity during the photo-Fenton process using a solar simulator were evaluated in this work. The AMX degradation was favored in the presence of the potassium ferrioxalate complex (FeOx) when compared to FeSO(4). Total oxidation of AMX in the presence of FeOx was obtained after 5 min, while 15 min were necessary using FeSO4. The results obtained with Daphnia magna biossays showed that the toxicity decreased from 65 to 5% after 90 min of irradiation in the presence of FeSO(4). However, it increased again to a maximum of 100% after 150 min, what indicates the generation of more toxic intermediates than AMX, reaching 45% after 240 min. However, using FeOx, the inhibition of mobility varied between 100 and 70% during treatment, probably due to the presence of oxalate, which is toxic to the neonates. After 240 min, between 73 and 81% TOC removal was observed. Different pathways of AMX degradation were suggested including the opening of the four-membered beta-lactamic ring and further oxidations of the methyl group to aldehyde and/or hydroxylation of the benzoic ring, generating other intermediates after bound cleavage between different atoms and further oxidation to carboxylates such acetate, oxalate and propionate, besides the generation of nitrate and ammonium. (C) 2010 Elsevier Ltd. All rights reserved. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-01-01 2014-05-20T15:34:35Z 2014-05-20T15:34:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.watres.2010.10.029 Water Research. Oxford: Pergamon-Elsevier B.V. Ltd, v. 45, n. 3, p. 1394-1402, 2011. 0043-1354 http://hdl.handle.net/11449/42589 10.1016/j.watres.2010.10.029 WOS:000287054500042 WOS000287054500042.pdf |
url |
http://dx.doi.org/10.1016/j.watres.2010.10.029 http://hdl.handle.net/11449/42589 |
identifier_str_mv |
Water Research. Oxford: Pergamon-Elsevier B.V. Ltd, v. 45, n. 3, p. 1394-1402, 2011. 0043-1354 10.1016/j.watres.2010.10.029 WOS:000287054500042 WOS000287054500042.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Water Research 7.051 2,601 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1394-1402 application/pdf |
dc.publisher.none.fl_str_mv |
Pergamon-Elsevier B.V. Ltd |
publisher.none.fl_str_mv |
Pergamon-Elsevier B.V. Ltd |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129546540548096 |