The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities

Detalhes bibliográficos
Autor(a) principal: de Freitas Araújo, Marcelo Gonzaga
Data de Publicação: 2015
Outros Autores: Bauab, Tais Maria [UNESP]
Tipo de documento: Capítulo de livro
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/232485
Resumo: Luteolin is a flavonoid found in several fruits and vegetables in significant amounts and number of biological properties of this phenolic was described, including the antioxidant activity. Several biological activities protect against the harmful action of reactive oxygen species (ROS), and here we focused our attention on the relationship between the biological activities of luteolin and their antioxidant properties. In this study, the antioxidant, antimicrobial, hemolytic and cytotoxicity activities were evaluated. Significant antioxidant activity was demonstrated and luteolin was effective against all bacteria and Candida strains tested, and showed an ability to inhibit hyphal formation. Non-hemolytic and antiproliferative activity could be demonstrated. The flavonoid showed a significant antioxidant activity, and it seems be essential for antibacterial, antifungal, non-hemolytic and antiproliferative activities.
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spelling The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activitiesLuteolin is a flavonoid found in several fruits and vegetables in significant amounts and number of biological properties of this phenolic was described, including the antioxidant activity. Several biological activities protect against the harmful action of reactive oxygen species (ROS), and here we focused our attention on the relationship between the biological activities of luteolin and their antioxidant properties. In this study, the antioxidant, antimicrobial, hemolytic and cytotoxicity activities were evaluated. Significant antioxidant activity was demonstrated and luteolin was effective against all bacteria and Candida strains tested, and showed an ability to inhibit hyphal formation. Non-hemolytic and antiproliferative activity could be demonstrated. The flavonoid showed a significant antioxidant activity, and it seems be essential for antibacterial, antifungal, non-hemolytic and antiproliferative activities.Universidade Federal de São João Del-Rei, Campus Centro Oeste - Dona LinduFaculdade de Ciências Farmacêuticas Universidade Estadual Paulista 'Julio de Mesquita Filho', Campus de AraraquaraFaculdade de Ciências Farmacêuticas Universidade Estadual Paulista 'Julio de Mesquita Filho', Campus de AraraquaraUniversidade Federal de São João Del-ReiUniversidade Estadual Paulista (UNESP)de Freitas Araújo, Marcelo GonzagaBauab, Tais Maria [UNESP]2022-04-29T17:14:47Z2022-04-29T17:14:47Z2015-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart1-16Luteolin: Natural Occurrences, Therapeutic Applications and Health Effects, p. 1-16.http://hdl.handle.net/11449/2324852-s2.0-84955635001Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengLuteolin: Natural Occurrences, Therapeutic Applications and Health Effectsinfo:eu-repo/semantics/openAccess2024-06-24T13:08:36Zoai:repositorio.unesp.br:11449/232485Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:06:41.982845Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities
title The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities
spellingShingle The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities
de Freitas Araújo, Marcelo Gonzaga
title_short The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities
title_full The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities
title_fullStr The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities
title_full_unstemmed The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities
title_sort The antioxidant property of luteolin and its correlation among antimicrobial, hemolytic, and antiproliferative activities
author de Freitas Araújo, Marcelo Gonzaga
author_facet de Freitas Araújo, Marcelo Gonzaga
Bauab, Tais Maria [UNESP]
author_role author
author2 Bauab, Tais Maria [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Federal de São João Del-Rei
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv de Freitas Araújo, Marcelo Gonzaga
Bauab, Tais Maria [UNESP]
description Luteolin is a flavonoid found in several fruits and vegetables in significant amounts and number of biological properties of this phenolic was described, including the antioxidant activity. Several biological activities protect against the harmful action of reactive oxygen species (ROS), and here we focused our attention on the relationship between the biological activities of luteolin and their antioxidant properties. In this study, the antioxidant, antimicrobial, hemolytic and cytotoxicity activities were evaluated. Significant antioxidant activity was demonstrated and luteolin was effective against all bacteria and Candida strains tested, and showed an ability to inhibit hyphal formation. Non-hemolytic and antiproliferative activity could be demonstrated. The flavonoid showed a significant antioxidant activity, and it seems be essential for antibacterial, antifungal, non-hemolytic and antiproliferative activities.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-01
2022-04-29T17:14:47Z
2022-04-29T17:14:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bookPart
format bookPart
status_str publishedVersion
dc.identifier.uri.fl_str_mv Luteolin: Natural Occurrences, Therapeutic Applications and Health Effects, p. 1-16.
http://hdl.handle.net/11449/232485
2-s2.0-84955635001
identifier_str_mv Luteolin: Natural Occurrences, Therapeutic Applications and Health Effects, p. 1-16.
2-s2.0-84955635001
url http://hdl.handle.net/11449/232485
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Luteolin: Natural Occurrences, Therapeutic Applications and Health Effects
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-16
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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