Biliary tract reconstruction using jejunal tube: An experimental study in dogs

• Autor(a) principal: Trentini, Eliane Anrain
• Data de Publicação: 2009
• Outros Autores: Crema, Eduardo, Llanos, Juan Carlos [UNESP], Lerco, Mauro Masson [UNESP], Magna, Luiz Alberto, Leonardi, Luiz Sergio
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/225456
• topic: Biliary tract surgical procedures; Monti principle; Obstructive jaundice

Background: To physiologically reconstruct the biliary tract, Crema et al suggested the application of the Monti principle to the biliary tract, already used in humans for the urinary tract. With this technique, a jejunal segment is transversely retubularized. This study aimed to evaluate the efficacy of jejunal tube interposition between the common bile duct and duodenum in dogs. Methods: Thirteen dogs underwent a laparoscopic common bile duct ligature, followed by a biliodigestive connection by jejunal tube interposition after one week. The levels of glutamic-pyruvic and glutamic-oxalacetic transaminases, total bilirubins, alkaline phosphatase and gamma-glutamyltransferase were assessed before surgery and thereafter weekly until euthanasia, which was performed 6 weeks after biliodigestive connection. Results: Data on 9 dogs were analyzed statistically. The dogs presented with obstructive jaundice after common bile duct ligature, as confirmed by biochemical examination. They showed a statistically significant reduction in cholestasis after biliodigestive connection by jejunal tube interposition and were healthy until the end of the experiment. Conclusion: A statistically significant reduction was seen in total bifirubin and canalicular enzymes (alkaline phosphatase and gamma-glutamyltransferase) in the 9 dogs 6 weeks after biliodigestive connetion by jejunal tube interposition. © 2009, Hepatobiliary Pancreat Dis Int. All rights reserved.