Repair of the axial dorsal skin flap in rats treated with ozonized oil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2023 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.26605/medvet-v17n1-5148 http://hdl.handle.net/11449/248805 |
Resumo: | Axial pattern flap represents an important option in reconstructive surgery, consisting of an artery and a direct cutaneous vein at their base and allowing a large area of skin to form the flap to cover the wound. However, the technique can present complications, mostly necrosis due to vascular involvement. In this context, ozone therapy can be used to accelerate the healing process of poorly vascularized and contaminated wounds. The objective of this article was to evaluate the effects and repair of the dorsal axial flap in Wistar rats at the receiving bed, using treatment with high-peroxidation ozonized oil. The study was carried out with 18 rats, divided into two groups with 9 animals: GG group (common sunflower oil) and GO group (ozonized sunflower oil). During the experimental period, macroscopic and microscopic evaluations were carried out, in order to observe the healing and repair of the surgical wound. Data were submitted to statistical analysis. The cosmetic appearance on GO was significantly better than GG. Blood vessel count, hemorrhage and reepithelialization were significantly higher in GO when compared to GG, while the presence of necrosis did not differ between groups. The mean total area of the flaps between the groups was statistically different, higher in the flaps in GO. The results showed that the use of ozonized oil in an axial pattern flap results in a favorable appearance and better reepithelialization in the treated group. |
id |
UNSP_b70c859ce104658e567ae693dd334ab1 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/248805 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Repair of the axial dorsal skin flap in rats treated with ozonized oilReparação do retalho axial dorsal em ratos tratados com óleo ozonizadoangiogenesiscollagenozone therapyreconstructive surgeryAxial pattern flap represents an important option in reconstructive surgery, consisting of an artery and a direct cutaneous vein at their base and allowing a large area of skin to form the flap to cover the wound. However, the technique can present complications, mostly necrosis due to vascular involvement. In this context, ozone therapy can be used to accelerate the healing process of poorly vascularized and contaminated wounds. The objective of this article was to evaluate the effects and repair of the dorsal axial flap in Wistar rats at the receiving bed, using treatment with high-peroxidation ozonized oil. The study was carried out with 18 rats, divided into two groups with 9 animals: GG group (common sunflower oil) and GO group (ozonized sunflower oil). During the experimental period, macroscopic and microscopic evaluations were carried out, in order to observe the healing and repair of the surgical wound. Data were submitted to statistical analysis. The cosmetic appearance on GO was significantly better than GG. Blood vessel count, hemorrhage and reepithelialization were significantly higher in GO when compared to GG, while the presence of necrosis did not differ between groups. The mean total area of the flaps between the groups was statistically different, higher in the flaps in GO. The results showed that the use of ozonized oil in an axial pattern flap results in a favorable appearance and better reepithelialization in the treated group.Departamento de Clínica e Cirurgia Veterinária Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista Júlio de Mesquita Filho – Campus Jaboticabal (UNESP), SPDepartamento de Clínica e Cirurgia Veterinária Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista Júlio de Mesquita Filho – Campus Jaboticabal (UNESP), SPUniversidade Estadual Paulista (UNESP)Nakamura, Aline Medeiros [UNESP]da Costa, Marcelo Carrijo [UNESP]Gómez, Jorge Luis Álvarez [UNESP]de Paiva, Felipe Noleto [UNESP]De Nardi, Andrigo Barboza [UNESP]2023-07-29T13:54:14Z2023-07-29T13:54:14Z2023-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article37-45http://dx.doi.org/10.26605/medvet-v17n1-5148Medicina Veterinaria (Brazil), v. 17, n. 1, p. 37-45, 2023.1809-4678http://hdl.handle.net/11449/24880510.26605/medvet-v17n1-51482-s2.0-85158987166Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporMedicina Veterinaria (Brazil)info:eu-repo/semantics/openAccess2024-06-06T14:10:07Zoai:repositorio.unesp.br:11449/248805Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:19:27.623774Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Repair of the axial dorsal skin flap in rats treated with ozonized oil Reparação do retalho axial dorsal em ratos tratados com óleo ozonizado |
title |
Repair of the axial dorsal skin flap in rats treated with ozonized oil |
spellingShingle |
Repair of the axial dorsal skin flap in rats treated with ozonized oil Nakamura, Aline Medeiros [UNESP] angiogenesis collagen ozone therapy reconstructive surgery |
title_short |
Repair of the axial dorsal skin flap in rats treated with ozonized oil |
title_full |
Repair of the axial dorsal skin flap in rats treated with ozonized oil |
title_fullStr |
Repair of the axial dorsal skin flap in rats treated with ozonized oil |
title_full_unstemmed |
Repair of the axial dorsal skin flap in rats treated with ozonized oil |
title_sort |
Repair of the axial dorsal skin flap in rats treated with ozonized oil |
author |
Nakamura, Aline Medeiros [UNESP] |
author_facet |
Nakamura, Aline Medeiros [UNESP] da Costa, Marcelo Carrijo [UNESP] Gómez, Jorge Luis Álvarez [UNESP] de Paiva, Felipe Noleto [UNESP] De Nardi, Andrigo Barboza [UNESP] |
author_role |
author |
author2 |
da Costa, Marcelo Carrijo [UNESP] Gómez, Jorge Luis Álvarez [UNESP] de Paiva, Felipe Noleto [UNESP] De Nardi, Andrigo Barboza [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Nakamura, Aline Medeiros [UNESP] da Costa, Marcelo Carrijo [UNESP] Gómez, Jorge Luis Álvarez [UNESP] de Paiva, Felipe Noleto [UNESP] De Nardi, Andrigo Barboza [UNESP] |
dc.subject.por.fl_str_mv |
angiogenesis collagen ozone therapy reconstructive surgery |
topic |
angiogenesis collagen ozone therapy reconstructive surgery |
description |
Axial pattern flap represents an important option in reconstructive surgery, consisting of an artery and a direct cutaneous vein at their base and allowing a large area of skin to form the flap to cover the wound. However, the technique can present complications, mostly necrosis due to vascular involvement. In this context, ozone therapy can be used to accelerate the healing process of poorly vascularized and contaminated wounds. The objective of this article was to evaluate the effects and repair of the dorsal axial flap in Wistar rats at the receiving bed, using treatment with high-peroxidation ozonized oil. The study was carried out with 18 rats, divided into two groups with 9 animals: GG group (common sunflower oil) and GO group (ozonized sunflower oil). During the experimental period, macroscopic and microscopic evaluations were carried out, in order to observe the healing and repair of the surgical wound. Data were submitted to statistical analysis. The cosmetic appearance on GO was significantly better than GG. Blood vessel count, hemorrhage and reepithelialization were significantly higher in GO when compared to GG, while the presence of necrosis did not differ between groups. The mean total area of the flaps between the groups was statistically different, higher in the flaps in GO. The results showed that the use of ozonized oil in an axial pattern flap results in a favorable appearance and better reepithelialization in the treated group. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T13:54:14Z 2023-07-29T13:54:14Z 2023-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.26605/medvet-v17n1-5148 Medicina Veterinaria (Brazil), v. 17, n. 1, p. 37-45, 2023. 1809-4678 http://hdl.handle.net/11449/248805 10.26605/medvet-v17n1-5148 2-s2.0-85158987166 |
url |
http://dx.doi.org/10.26605/medvet-v17n1-5148 http://hdl.handle.net/11449/248805 |
identifier_str_mv |
Medicina Veterinaria (Brazil), v. 17, n. 1, p. 37-45, 2023. 1809-4678 10.26605/medvet-v17n1-5148 2-s2.0-85158987166 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Medicina Veterinaria (Brazil) |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
37-45 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128919499440128 |