A new approach for professional dental bleaching using a polymeric catalyst primer
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1111/jerd.12972 http://hdl.handle.net/11449/249222 |
Resumo: | Objective: Evaluate the influence of a polymeric catalyst primer (PCP) on esthetic efficacy (EE), degradation kinetics of hydrogen peroxide (H2O2), and trans-amelodentinal cytotoxicity (TC) of bleaching gels. Materials and Methods: The following groups were established: G1: No treatment (NC, negative control); G2: PCP; G3: 10% H2O2; G4: PCP + 10% H2O2; G5: 20% H2O2; G6: PCP + 20% H2O2; G7: 35% H2O2 (positive control); G8: PCP + 35% H2O2. To determine EE, enamel/dentin discs (E/DDs) were stained and subjected or not to bleaching protocols for 45 min. To assess TC, the E/DDs were adapted to artificial pulp chambers. The extracts (culture medium + gel components diffused through E/DDs) were applied to odontoblast-like MDPC-23 cells. The viability (VB), oxidative stress (OxS), morphology (SEM), amount of H2O2 diffused and the production of hydroxyl radical (OH•) were assessed (two-way ANOVA/Tukey/paired Student t-test; p < 0.05). Results: The highest EE was found in G8 (p < 0.05), and G4, G6, and G7 did not differ statistically (p > 0.05). In G4, the limited H2O2 diffusion reduced OxS and increased cell VB (p < 0.05). Conclusions: Coating the enamel with PCP containing 10 mg/ml of manganese oxide before applying the 10% H2O2 bleaching gel maintains the EE of conventional in-office bleaching and minimizes the toxic effects of this esthetic therapy. Clinical Significance: Coating the enamel with a PCP before applying the bleaching gel may potentiate the EE of the conventional in-office tooth bleaching and reduce the toxicity of this professional therapy to the dental pulp. |
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A new approach for professional dental bleaching using a polymeric catalyst primercolor sciencedental materialsodontoblaststooth bleachingtoxicityObjective: Evaluate the influence of a polymeric catalyst primer (PCP) on esthetic efficacy (EE), degradation kinetics of hydrogen peroxide (H2O2), and trans-amelodentinal cytotoxicity (TC) of bleaching gels. Materials and Methods: The following groups were established: G1: No treatment (NC, negative control); G2: PCP; G3: 10% H2O2; G4: PCP + 10% H2O2; G5: 20% H2O2; G6: PCP + 20% H2O2; G7: 35% H2O2 (positive control); G8: PCP + 35% H2O2. To determine EE, enamel/dentin discs (E/DDs) were stained and subjected or not to bleaching protocols for 45 min. To assess TC, the E/DDs were adapted to artificial pulp chambers. The extracts (culture medium + gel components diffused through E/DDs) were applied to odontoblast-like MDPC-23 cells. The viability (VB), oxidative stress (OxS), morphology (SEM), amount of H2O2 diffused and the production of hydroxyl radical (OH•) were assessed (two-way ANOVA/Tukey/paired Student t-test; p < 0.05). Results: The highest EE was found in G8 (p < 0.05), and G4, G6, and G7 did not differ statistically (p > 0.05). In G4, the limited H2O2 diffusion reduced OxS and increased cell VB (p < 0.05). Conclusions: Coating the enamel with PCP containing 10 mg/ml of manganese oxide before applying the 10% H2O2 bleaching gel maintains the EE of conventional in-office bleaching and minimizes the toxic effects of this esthetic therapy. Clinical Significance: Coating the enamel with a PCP before applying the bleaching gel may potentiate the EE of the conventional in-office tooth bleaching and reduce the toxicity of this professional therapy to the dental pulp.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Department of Dental Materials and Prosthodontics School of Dentistry São Paulo State UniversityDepartment of Morphology Genetics Orthodontics and Pediatric Dentistry School of Dentistry São Paulo State UniversityDepartment of Physiology and Pathology School of Dentistry São Paulo State UniversityDepartment of Dental Materials and Prosthodontics School of Dentistry São Paulo State UniversityDepartment of Morphology Genetics Orthodontics and Pediatric Dentistry School of Dentistry São Paulo State UniversityDepartment of Physiology and Pathology School of Dentistry São Paulo State UniversityFAPESP: 2020/08882-6CNPq: 302047/2019-0CNPq: 408721/2018-9CAPES: Finance Code 001Universidade Estadual Paulista (UNESP)Dias, Marlon Ferreira [UNESP]Martins, Beatriz Voss [UNESP]de Oliveira Ribeiro, Rafael Antonio [UNESP]Leite, Maria Luísa [UNESP]Ortecho-Zuta, Uxua [UNESP]Hebling, Josimeri [UNESP]Costa, Carlos Alberto de Souza [UNESP]2023-07-29T14:32:10Z2023-07-29T14:32:10Z2023-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article406-415http://dx.doi.org/10.1111/jerd.12972Journal of Esthetic and Restorative Dentistry, v. 35, n. 2, p. 406-415, 2023.1708-82401496-4155http://hdl.handle.net/11449/24922210.1111/jerd.129722-s2.0-85139149502Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Esthetic and Restorative Dentistryinfo:eu-repo/semantics/openAccess2023-07-29T14:32:10Zoai:repositorio.unesp.br:11449/249222Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:36:53.727826Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
A new approach for professional dental bleaching using a polymeric catalyst primer |
title |
A new approach for professional dental bleaching using a polymeric catalyst primer |
spellingShingle |
A new approach for professional dental bleaching using a polymeric catalyst primer Dias, Marlon Ferreira [UNESP] color science dental materials odontoblasts tooth bleaching toxicity |
title_short |
A new approach for professional dental bleaching using a polymeric catalyst primer |
title_full |
A new approach for professional dental bleaching using a polymeric catalyst primer |
title_fullStr |
A new approach for professional dental bleaching using a polymeric catalyst primer |
title_full_unstemmed |
A new approach for professional dental bleaching using a polymeric catalyst primer |
title_sort |
A new approach for professional dental bleaching using a polymeric catalyst primer |
author |
Dias, Marlon Ferreira [UNESP] |
author_facet |
Dias, Marlon Ferreira [UNESP] Martins, Beatriz Voss [UNESP] de Oliveira Ribeiro, Rafael Antonio [UNESP] Leite, Maria Luísa [UNESP] Ortecho-Zuta, Uxua [UNESP] Hebling, Josimeri [UNESP] Costa, Carlos Alberto de Souza [UNESP] |
author_role |
author |
author2 |
Martins, Beatriz Voss [UNESP] de Oliveira Ribeiro, Rafael Antonio [UNESP] Leite, Maria Luísa [UNESP] Ortecho-Zuta, Uxua [UNESP] Hebling, Josimeri [UNESP] Costa, Carlos Alberto de Souza [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Dias, Marlon Ferreira [UNESP] Martins, Beatriz Voss [UNESP] de Oliveira Ribeiro, Rafael Antonio [UNESP] Leite, Maria Luísa [UNESP] Ortecho-Zuta, Uxua [UNESP] Hebling, Josimeri [UNESP] Costa, Carlos Alberto de Souza [UNESP] |
dc.subject.por.fl_str_mv |
color science dental materials odontoblasts tooth bleaching toxicity |
topic |
color science dental materials odontoblasts tooth bleaching toxicity |
description |
Objective: Evaluate the influence of a polymeric catalyst primer (PCP) on esthetic efficacy (EE), degradation kinetics of hydrogen peroxide (H2O2), and trans-amelodentinal cytotoxicity (TC) of bleaching gels. Materials and Methods: The following groups were established: G1: No treatment (NC, negative control); G2: PCP; G3: 10% H2O2; G4: PCP + 10% H2O2; G5: 20% H2O2; G6: PCP + 20% H2O2; G7: 35% H2O2 (positive control); G8: PCP + 35% H2O2. To determine EE, enamel/dentin discs (E/DDs) were stained and subjected or not to bleaching protocols for 45 min. To assess TC, the E/DDs were adapted to artificial pulp chambers. The extracts (culture medium + gel components diffused through E/DDs) were applied to odontoblast-like MDPC-23 cells. The viability (VB), oxidative stress (OxS), morphology (SEM), amount of H2O2 diffused and the production of hydroxyl radical (OH•) were assessed (two-way ANOVA/Tukey/paired Student t-test; p < 0.05). Results: The highest EE was found in G8 (p < 0.05), and G4, G6, and G7 did not differ statistically (p > 0.05). In G4, the limited H2O2 diffusion reduced OxS and increased cell VB (p < 0.05). Conclusions: Coating the enamel with PCP containing 10 mg/ml of manganese oxide before applying the 10% H2O2 bleaching gel maintains the EE of conventional in-office bleaching and minimizes the toxic effects of this esthetic therapy. Clinical Significance: Coating the enamel with a PCP before applying the bleaching gel may potentiate the EE of the conventional in-office tooth bleaching and reduce the toxicity of this professional therapy to the dental pulp. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T14:32:10Z 2023-07-29T14:32:10Z 2023-03-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1111/jerd.12972 Journal of Esthetic and Restorative Dentistry, v. 35, n. 2, p. 406-415, 2023. 1708-8240 1496-4155 http://hdl.handle.net/11449/249222 10.1111/jerd.12972 2-s2.0-85139149502 |
url |
http://dx.doi.org/10.1111/jerd.12972 http://hdl.handle.net/11449/249222 |
identifier_str_mv |
Journal of Esthetic and Restorative Dentistry, v. 35, n. 2, p. 406-415, 2023. 1708-8240 1496-4155 10.1111/jerd.12972 2-s2.0-85139149502 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Esthetic and Restorative Dentistry |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
406-415 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129227523883008 |