Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.revistas.usp.br/bjvras/article/view/26514 http://hdl.handle.net/11449/69372 |
Resumo: | The aim of this study was to evaluate the pre-emptive effect of epidural ketamine S (+) (SK) or racemic ketamine (RK) administration, in post-incisional pain in horses. Were used in a blinded, randomized experimental study, sixteen mixed breed mares, 6±2 years old, weighting 273.2±42.0 kg. An epidural catheter was inserted 24 hours before the trials. The thigh region was shaved bilaterally, and mechanical cutaneous sensibility was measured using von Frey filaments (T-30). Using the left side as the control one, local anesthesia was performed at the right side. Twenty-five minutes later, SK was injected in G1 or RK in G2 through the epidural catheter. Five minutes after the ketamine injection, a 10 cm skin incision was made on the right side, and then sutured. Mechanical post-incisional pain was measured using von Frey filaments, at 1, 3 and 5 cm around the incision at 15 minutes intervals, for 2 hours, then 4, 6 and 8 hours after suturing. No changes were observed in the heart and respiratory rate and rectal temperature among groups or times of each group. Hind limb ataxia was observed in 62.5% and 12.5% of G1 and G2 respectively. SK and RK reduced cutaneous sensibility in the right and the left sides to mechanical postincisional pain during all time of experiment. Epidural SK and RK produce similar post-incisional analgesic effects, did not interfere in the cardio-respiratory parameters. The SK induces more intense ataxia in mares and presents a larger analgesic potency in the first 60 minutes after the administration. |
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Repositório Institucional da UNESP |
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Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinosPreemptive effects of epidural s (+) - ketamine or ketamine in the horse's postincisional painHorsesHyperalgesiaPainS (+) - KetamineVon FreyEquidaeThe aim of this study was to evaluate the pre-emptive effect of epidural ketamine S (+) (SK) or racemic ketamine (RK) administration, in post-incisional pain in horses. Were used in a blinded, randomized experimental study, sixteen mixed breed mares, 6±2 years old, weighting 273.2±42.0 kg. An epidural catheter was inserted 24 hours before the trials. The thigh region was shaved bilaterally, and mechanical cutaneous sensibility was measured using von Frey filaments (T-30). Using the left side as the control one, local anesthesia was performed at the right side. Twenty-five minutes later, SK was injected in G1 or RK in G2 through the epidural catheter. Five minutes after the ketamine injection, a 10 cm skin incision was made on the right side, and then sutured. Mechanical post-incisional pain was measured using von Frey filaments, at 1, 3 and 5 cm around the incision at 15 minutes intervals, for 2 hours, then 4, 6 and 8 hours after suturing. No changes were observed in the heart and respiratory rate and rectal temperature among groups or times of each group. Hind limb ataxia was observed in 62.5% and 12.5% of G1 and G2 respectively. SK and RK reduced cutaneous sensibility in the right and the left sides to mechanical postincisional pain during all time of experiment. Epidural SK and RK produce similar post-incisional analgesic effects, did not interfere in the cardio-respiratory parameters. The SK induces more intense ataxia in mares and presents a larger analgesic potency in the first 60 minutes after the administration.Departamento de Clínica e Cirurgia Veterinária Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista, Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900 - Jaboticabal - SPDepartamento de Clínica e Cirurgia Veterinária Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista, Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900 - Jaboticabal - SPUniversidade Estadual Paulista (Unesp)Oleskovicz, Nilson [UNESP]Valadão, Carlos Augusto Araújo [UNESP]Duquem M, Juan Carlos [UNESP]Farias, Anderson [UNESP]2014-05-27T11:22:19Z2014-05-27T11:22:19Z2006-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article24-32application/pdfhttp://www.revistas.usp.br/bjvras/article/view/26514Brazilian Journal of Veterinary Research and Animal Science, v. 43, n. 1, p. 24-32, 2006.1413-95961678-4456http://hdl.handle.net/11449/693722-s2.0-781493505292-s2.0-78149350529.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporBrazilian Journal of Veterinary Research and Animal Science0,2250,225info:eu-repo/semantics/openAccess2024-06-06T14:09:26Zoai:repositorio.unesp.br:11449/69372Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:30:11.416554Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos Preemptive effects of epidural s (+) - ketamine or ketamine in the horse's postincisional pain |
title |
Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos |
spellingShingle |
Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos Oleskovicz, Nilson [UNESP] Horses Hyperalgesia Pain S (+) - Ketamine Von Frey Equidae |
title_short |
Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos |
title_full |
Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos |
title_fullStr |
Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos |
title_full_unstemmed |
Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos |
title_sort |
Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos |
author |
Oleskovicz, Nilson [UNESP] |
author_facet |
Oleskovicz, Nilson [UNESP] Valadão, Carlos Augusto Araújo [UNESP] Duquem M, Juan Carlos [UNESP] Farias, Anderson [UNESP] |
author_role |
author |
author2 |
Valadão, Carlos Augusto Araújo [UNESP] Duquem M, Juan Carlos [UNESP] Farias, Anderson [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Oleskovicz, Nilson [UNESP] Valadão, Carlos Augusto Araújo [UNESP] Duquem M, Juan Carlos [UNESP] Farias, Anderson [UNESP] |
dc.subject.por.fl_str_mv |
Horses Hyperalgesia Pain S (+) - Ketamine Von Frey Equidae |
topic |
Horses Hyperalgesia Pain S (+) - Ketamine Von Frey Equidae |
description |
The aim of this study was to evaluate the pre-emptive effect of epidural ketamine S (+) (SK) or racemic ketamine (RK) administration, in post-incisional pain in horses. Were used in a blinded, randomized experimental study, sixteen mixed breed mares, 6±2 years old, weighting 273.2±42.0 kg. An epidural catheter was inserted 24 hours before the trials. The thigh region was shaved bilaterally, and mechanical cutaneous sensibility was measured using von Frey filaments (T-30). Using the left side as the control one, local anesthesia was performed at the right side. Twenty-five minutes later, SK was injected in G1 or RK in G2 through the epidural catheter. Five minutes after the ketamine injection, a 10 cm skin incision was made on the right side, and then sutured. Mechanical post-incisional pain was measured using von Frey filaments, at 1, 3 and 5 cm around the incision at 15 minutes intervals, for 2 hours, then 4, 6 and 8 hours after suturing. No changes were observed in the heart and respiratory rate and rectal temperature among groups or times of each group. Hind limb ataxia was observed in 62.5% and 12.5% of G1 and G2 respectively. SK and RK reduced cutaneous sensibility in the right and the left sides to mechanical postincisional pain during all time of experiment. Epidural SK and RK produce similar post-incisional analgesic effects, did not interfere in the cardio-respiratory parameters. The SK induces more intense ataxia in mares and presents a larger analgesic potency in the first 60 minutes after the administration. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-12-01 2014-05-27T11:22:19Z 2014-05-27T11:22:19Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.revistas.usp.br/bjvras/article/view/26514 Brazilian Journal of Veterinary Research and Animal Science, v. 43, n. 1, p. 24-32, 2006. 1413-9596 1678-4456 http://hdl.handle.net/11449/69372 2-s2.0-78149350529 2-s2.0-78149350529.pdf |
url |
http://www.revistas.usp.br/bjvras/article/view/26514 http://hdl.handle.net/11449/69372 |
identifier_str_mv |
Brazilian Journal of Veterinary Research and Animal Science, v. 43, n. 1, p. 24-32, 2006. 1413-9596 1678-4456 2-s2.0-78149350529 2-s2.0-78149350529.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science 0,225 0,225 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
24-32 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128662554279936 |