Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos

Detalhes bibliográficos
Autor(a) principal: Oleskovicz, Nilson [UNESP]
Data de Publicação: 2006
Outros Autores: Valadão, Carlos Augusto Araújo [UNESP], Duquem M, Juan Carlos [UNESP], Farias, Anderson [UNESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.revistas.usp.br/bjvras/article/view/26514
http://hdl.handle.net/11449/69372
Resumo: The aim of this study was to evaluate the pre-emptive effect of epidural ketamine S (+) (SK) or racemic ketamine (RK) administration, in post-incisional pain in horses. Were used in a blinded, randomized experimental study, sixteen mixed breed mares, 6±2 years old, weighting 273.2±42.0 kg. An epidural catheter was inserted 24 hours before the trials. The thigh region was shaved bilaterally, and mechanical cutaneous sensibility was measured using von Frey filaments (T-30). Using the left side as the control one, local anesthesia was performed at the right side. Twenty-five minutes later, SK was injected in G1 or RK in G2 through the epidural catheter. Five minutes after the ketamine injection, a 10 cm skin incision was made on the right side, and then sutured. Mechanical post-incisional pain was measured using von Frey filaments, at 1, 3 and 5 cm around the incision at 15 minutes intervals, for 2 hours, then 4, 6 and 8 hours after suturing. No changes were observed in the heart and respiratory rate and rectal temperature among groups or times of each group. Hind limb ataxia was observed in 62.5% and 12.5% of G1 and G2 respectively. SK and RK reduced cutaneous sensibility in the right and the left sides to mechanical postincisional pain during all time of experiment. Epidural SK and RK produce similar post-incisional analgesic effects, did not interfere in the cardio-respiratory parameters. The SK induces more intense ataxia in mares and presents a larger analgesic potency in the first 60 minutes after the administration.
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spelling Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinosPreemptive effects of epidural s (+) - ketamine or ketamine in the horse's postincisional painHorsesHyperalgesiaPainS (+) - KetamineVon FreyEquidaeThe aim of this study was to evaluate the pre-emptive effect of epidural ketamine S (+) (SK) or racemic ketamine (RK) administration, in post-incisional pain in horses. Were used in a blinded, randomized experimental study, sixteen mixed breed mares, 6±2 years old, weighting 273.2±42.0 kg. An epidural catheter was inserted 24 hours before the trials. The thigh region was shaved bilaterally, and mechanical cutaneous sensibility was measured using von Frey filaments (T-30). Using the left side as the control one, local anesthesia was performed at the right side. Twenty-five minutes later, SK was injected in G1 or RK in G2 through the epidural catheter. Five minutes after the ketamine injection, a 10 cm skin incision was made on the right side, and then sutured. Mechanical post-incisional pain was measured using von Frey filaments, at 1, 3 and 5 cm around the incision at 15 minutes intervals, for 2 hours, then 4, 6 and 8 hours after suturing. No changes were observed in the heart and respiratory rate and rectal temperature among groups or times of each group. Hind limb ataxia was observed in 62.5% and 12.5% of G1 and G2 respectively. SK and RK reduced cutaneous sensibility in the right and the left sides to mechanical postincisional pain during all time of experiment. Epidural SK and RK produce similar post-incisional analgesic effects, did not interfere in the cardio-respiratory parameters. The SK induces more intense ataxia in mares and presents a larger analgesic potency in the first 60 minutes after the administration.Departamento de Clínica e Cirurgia Veterinária Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista, Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900 - Jaboticabal - SPDepartamento de Clínica e Cirurgia Veterinária Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista, Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900 - Jaboticabal - SPUniversidade Estadual Paulista (Unesp)Oleskovicz, Nilson [UNESP]Valadão, Carlos Augusto Araújo [UNESP]Duquem M, Juan Carlos [UNESP]Farias, Anderson [UNESP]2014-05-27T11:22:19Z2014-05-27T11:22:19Z2006-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article24-32application/pdfhttp://www.revistas.usp.br/bjvras/article/view/26514Brazilian Journal of Veterinary Research and Animal Science, v. 43, n. 1, p. 24-32, 2006.1413-95961678-4456http://hdl.handle.net/11449/693722-s2.0-781493505292-s2.0-78149350529.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporBrazilian Journal of Veterinary Research and Animal Science0,2250,225info:eu-repo/semantics/openAccess2024-06-06T14:09:26Zoai:repositorio.unesp.br:11449/69372Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:30:11.416554Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
Preemptive effects of epidural s (+) - ketamine or ketamine in the horse's postincisional pain
title Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
spellingShingle Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
Oleskovicz, Nilson [UNESP]
Horses
Hyperalgesia
Pain
S (+) - Ketamine
Von Frey
Equidae
title_short Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
title_full Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
title_fullStr Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
title_full_unstemmed Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
title_sort Injeção epidural de cetamina ou cetamina levógira no controle da dor pós-incisional, em eqüinos
author Oleskovicz, Nilson [UNESP]
author_facet Oleskovicz, Nilson [UNESP]
Valadão, Carlos Augusto Araújo [UNESP]
Duquem M, Juan Carlos [UNESP]
Farias, Anderson [UNESP]
author_role author
author2 Valadão, Carlos Augusto Araújo [UNESP]
Duquem M, Juan Carlos [UNESP]
Farias, Anderson [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Oleskovicz, Nilson [UNESP]
Valadão, Carlos Augusto Araújo [UNESP]
Duquem M, Juan Carlos [UNESP]
Farias, Anderson [UNESP]
dc.subject.por.fl_str_mv Horses
Hyperalgesia
Pain
S (+) - Ketamine
Von Frey
Equidae
topic Horses
Hyperalgesia
Pain
S (+) - Ketamine
Von Frey
Equidae
description The aim of this study was to evaluate the pre-emptive effect of epidural ketamine S (+) (SK) or racemic ketamine (RK) administration, in post-incisional pain in horses. Were used in a blinded, randomized experimental study, sixteen mixed breed mares, 6±2 years old, weighting 273.2±42.0 kg. An epidural catheter was inserted 24 hours before the trials. The thigh region was shaved bilaterally, and mechanical cutaneous sensibility was measured using von Frey filaments (T-30). Using the left side as the control one, local anesthesia was performed at the right side. Twenty-five minutes later, SK was injected in G1 or RK in G2 through the epidural catheter. Five minutes after the ketamine injection, a 10 cm skin incision was made on the right side, and then sutured. Mechanical post-incisional pain was measured using von Frey filaments, at 1, 3 and 5 cm around the incision at 15 minutes intervals, for 2 hours, then 4, 6 and 8 hours after suturing. No changes were observed in the heart and respiratory rate and rectal temperature among groups or times of each group. Hind limb ataxia was observed in 62.5% and 12.5% of G1 and G2 respectively. SK and RK reduced cutaneous sensibility in the right and the left sides to mechanical postincisional pain during all time of experiment. Epidural SK and RK produce similar post-incisional analgesic effects, did not interfere in the cardio-respiratory parameters. The SK induces more intense ataxia in mares and presents a larger analgesic potency in the first 60 minutes after the administration.
publishDate 2006
dc.date.none.fl_str_mv 2006-12-01
2014-05-27T11:22:19Z
2014-05-27T11:22:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.revistas.usp.br/bjvras/article/view/26514
Brazilian Journal of Veterinary Research and Animal Science, v. 43, n. 1, p. 24-32, 2006.
1413-9596
1678-4456
http://hdl.handle.net/11449/69372
2-s2.0-78149350529
2-s2.0-78149350529.pdf
url http://www.revistas.usp.br/bjvras/article/view/26514
http://hdl.handle.net/11449/69372
identifier_str_mv Brazilian Journal of Veterinary Research and Animal Science, v. 43, n. 1, p. 24-32, 2006.
1413-9596
1678-4456
2-s2.0-78149350529
2-s2.0-78149350529.pdf
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science
0,225
0,225
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 24-32
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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