Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3389/fphys.2017.00710 http://hdl.handle.net/11449/159814 |
Resumo: | The aim of this study was to evaluate the effects of taurine and chocolate milksupplementation on oxidative stress and protein metabolism markers, and aerobicparameters in triathletes. Methods: A double-blind, crossover study was conducted with 10 male triathletes,aged 30.9 +/- 1.3 year, height 1.79 +/- 0.01 m and body weight 77.45 +/- 2.4 kg. Threegrams of taurine and 400 ml of chocolate milk (TAUchoc), or a placebo (chocolate milk)(CHOC) was ingested post exercise for 8 weeks. Oxidative stress marker levels, and 24 hurinary nitrogen, creatinine, and urea excretion were measured before and after 8 weeksof training and supplementation with TAUchoc or CHOC. A maximal incremental runningtest on a treadmill was performed in order to evaluate aerobic parameters: Vmax, heartrate (HR) and rate of perceived exertion (RPE). Results: TAUchoc treatment during the 8 weeks resulted in increased taurine plasmalevels (PRE 201.32 +/- 29.03 mu mol/L and POST 234.36 +/- 35.51 mu mol/L, p=0.01),decreased malondialdehyde levels (19.4%, p=0.03) and urinary nitrogen excretion(-33%, p=0.03), and promoted positive nitrogen balance (p=0.01). There wereno changes in reduced glutathione (TAUchoc PRE 0.72 +/- 0.08 mmol/L and POST0.83 +/- 0.08 mmol/L; CHOC PRE 0.69 +/- 0.08 mmol/L and POST 0.81 +/- 0.06 mmol/L),vitamin E plasma levels (TAUchoc PRE 33.99 +/- 2.52 mu mol/L and 35.95 +/- 2.80 mu mol/Land CHOC PRE 31.48 +/- 2.12 mu mol/L and POST 33.77 +/- 3.64 mu mol/L), or aerobicparameters, which were obtained in the last phase of the maximal incremental runningtest (Vmax TAUchoc PRE 13 +/- 1.4 km/h and POST 13.22 +/- 1.34 km/h; CHOC PRE13.11 +/- 2.34 km/h and POST 13.11 +/- 2.72 km/h), the heart rate values were TAUchocPRE 181.89 +/- 24.18 bpm and POST 168.89 +/- 46.56 bpm; CHOC PRE 181.56 +/- 2.14bpm and POST 179.78 +/- 3.4 bpm, and the RPE were TAUchoc PRE 8.33 +/- 2.4 AUand POST 9.1 +/- 2.1 AU; CHOC PRE 8.11 +/- 4.94 AU and POST 8.78 +/- 2.78 AU). Conclusion: Taurine supplementation did not improve aerobic parameters, but waseffective in increasing taurine plasma levels and decreasing oxidative stress markers,which suggests that taurine may prevent oxidative stress in triathletes |
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Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercisetriathlontaurinechocolate milk and aerobic parametersThe aim of this study was to evaluate the effects of taurine and chocolate milksupplementation on oxidative stress and protein metabolism markers, and aerobicparameters in triathletes. Methods: A double-blind, crossover study was conducted with 10 male triathletes,aged 30.9 +/- 1.3 year, height 1.79 +/- 0.01 m and body weight 77.45 +/- 2.4 kg. Threegrams of taurine and 400 ml of chocolate milk (TAUchoc), or a placebo (chocolate milk)(CHOC) was ingested post exercise for 8 weeks. Oxidative stress marker levels, and 24 hurinary nitrogen, creatinine, and urea excretion were measured before and after 8 weeksof training and supplementation with TAUchoc or CHOC. A maximal incremental runningtest on a treadmill was performed in order to evaluate aerobic parameters: Vmax, heartrate (HR) and rate of perceived exertion (RPE). Results: TAUchoc treatment during the 8 weeks resulted in increased taurine plasmalevels (PRE 201.32 +/- 29.03 mu mol/L and POST 234.36 +/- 35.51 mu mol/L, p=0.01),decreased malondialdehyde levels (19.4%, p=0.03) and urinary nitrogen excretion(-33%, p=0.03), and promoted positive nitrogen balance (p=0.01). There wereno changes in reduced glutathione (TAUchoc PRE 0.72 +/- 0.08 mmol/L and POST0.83 +/- 0.08 mmol/L; CHOC PRE 0.69 +/- 0.08 mmol/L and POST 0.81 +/- 0.06 mmol/L),vitamin E plasma levels (TAUchoc PRE 33.99 +/- 2.52 mu mol/L and 35.95 +/- 2.80 mu mol/Land CHOC PRE 31.48 +/- 2.12 mu mol/L and POST 33.77 +/- 3.64 mu mol/L), or aerobicparameters, which were obtained in the last phase of the maximal incremental runningtest (Vmax TAUchoc PRE 13 +/- 1.4 km/h and POST 13.22 +/- 1.34 km/h; CHOC PRE13.11 +/- 2.34 km/h and POST 13.11 +/- 2.72 km/h), the heart rate values were TAUchocPRE 181.89 +/- 24.18 bpm and POST 168.89 +/- 46.56 bpm; CHOC PRE 181.56 +/- 2.14bpm and POST 179.78 +/- 3.4 bpm, and the RPE were TAUchoc PRE 8.33 +/- 2.4 AUand POST 9.1 +/- 2.1 AU; CHOC PRE 8.11 +/- 4.94 AU and POST 8.78 +/- 2.78 AU). Conclusion: Taurine supplementation did not improve aerobic parameters, but waseffective in increasing taurine plasma levels and decreasing oxidative stress markers,which suggests that taurine may prevent oxidative stress in triathletesSao Paulo State Univ, Fac Pharmaceut Sci, Postgrad Program Food & Nutr, Sao Paulo, BrazilCent Washington Univ, Dept Nutr Exercise & Hlth Sci, Ellensburg, WA USAUniv Sao Paulo, Ribeirao Preto Med Sch, Dept Internal Med, Ribeirao Preto, BrazilUniv Sao Paulo, Sch Phys Educ & Sports Ribeirao Preto, Ribeirao Preto, BrazilSao Paulo State Univ, Fac Pharmaceut Sci, Postgrad Program Food & Nutr, Sao Paulo, BrazilFrontiers Media SaUniversidade Estadual Paulista (Unesp)Cent Washington UnivUniversidade de São Paulo (USP)De Carvalho, Flavia G. [UNESP]Galan, Bryan S. M. [UNESP]Santos, Priscila C. [UNESP]Pritchett, KellyPfrimer, KarinaFerriolli, EduardoPapoti, MarceloMarchini, Julio S.Freitas, Ellen C. de [UNESP]2018-11-26T15:45:21Z2018-11-26T15:45:21Z2017-09-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article8application/pdfhttp://dx.doi.org/10.3389/fphys.2017.00710Frontiers In Physiology. Lausanne: Frontiers Media Sa, v. 8, 8 p., 2017.1664-042Xhttp://hdl.handle.net/11449/15981410.3389/fphys.2017.00710WOS:000411439700001WOS000411439700001.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFrontiers In Physiologyinfo:eu-repo/semantics/openAccess2024-01-22T06:28:51Zoai:repositorio.unesp.br:11449/159814Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-22T06:28:51Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise |
title |
Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise |
spellingShingle |
Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise De Carvalho, Flavia G. [UNESP] triathlon taurine chocolate milk and aerobic parameters |
title_short |
Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise |
title_full |
Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise |
title_fullStr |
Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise |
title_full_unstemmed |
Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise |
title_sort |
Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise |
author |
De Carvalho, Flavia G. [UNESP] |
author_facet |
De Carvalho, Flavia G. [UNESP] Galan, Bryan S. M. [UNESP] Santos, Priscila C. [UNESP] Pritchett, Kelly Pfrimer, Karina Ferriolli, Eduardo Papoti, Marcelo Marchini, Julio S. Freitas, Ellen C. de [UNESP] |
author_role |
author |
author2 |
Galan, Bryan S. M. [UNESP] Santos, Priscila C. [UNESP] Pritchett, Kelly Pfrimer, Karina Ferriolli, Eduardo Papoti, Marcelo Marchini, Julio S. Freitas, Ellen C. de [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Cent Washington Univ Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
De Carvalho, Flavia G. [UNESP] Galan, Bryan S. M. [UNESP] Santos, Priscila C. [UNESP] Pritchett, Kelly Pfrimer, Karina Ferriolli, Eduardo Papoti, Marcelo Marchini, Julio S. Freitas, Ellen C. de [UNESP] |
dc.subject.por.fl_str_mv |
triathlon taurine chocolate milk and aerobic parameters |
topic |
triathlon taurine chocolate milk and aerobic parameters |
description |
The aim of this study was to evaluate the effects of taurine and chocolate milksupplementation on oxidative stress and protein metabolism markers, and aerobicparameters in triathletes. Methods: A double-blind, crossover study was conducted with 10 male triathletes,aged 30.9 +/- 1.3 year, height 1.79 +/- 0.01 m and body weight 77.45 +/- 2.4 kg. Threegrams of taurine and 400 ml of chocolate milk (TAUchoc), or a placebo (chocolate milk)(CHOC) was ingested post exercise for 8 weeks. Oxidative stress marker levels, and 24 hurinary nitrogen, creatinine, and urea excretion were measured before and after 8 weeksof training and supplementation with TAUchoc or CHOC. A maximal incremental runningtest on a treadmill was performed in order to evaluate aerobic parameters: Vmax, heartrate (HR) and rate of perceived exertion (RPE). Results: TAUchoc treatment during the 8 weeks resulted in increased taurine plasmalevels (PRE 201.32 +/- 29.03 mu mol/L and POST 234.36 +/- 35.51 mu mol/L, p=0.01),decreased malondialdehyde levels (19.4%, p=0.03) and urinary nitrogen excretion(-33%, p=0.03), and promoted positive nitrogen balance (p=0.01). There wereno changes in reduced glutathione (TAUchoc PRE 0.72 +/- 0.08 mmol/L and POST0.83 +/- 0.08 mmol/L; CHOC PRE 0.69 +/- 0.08 mmol/L and POST 0.81 +/- 0.06 mmol/L),vitamin E plasma levels (TAUchoc PRE 33.99 +/- 2.52 mu mol/L and 35.95 +/- 2.80 mu mol/Land CHOC PRE 31.48 +/- 2.12 mu mol/L and POST 33.77 +/- 3.64 mu mol/L), or aerobicparameters, which were obtained in the last phase of the maximal incremental runningtest (Vmax TAUchoc PRE 13 +/- 1.4 km/h and POST 13.22 +/- 1.34 km/h; CHOC PRE13.11 +/- 2.34 km/h and POST 13.11 +/- 2.72 km/h), the heart rate values were TAUchocPRE 181.89 +/- 24.18 bpm and POST 168.89 +/- 46.56 bpm; CHOC PRE 181.56 +/- 2.14bpm and POST 179.78 +/- 3.4 bpm, and the RPE were TAUchoc PRE 8.33 +/- 2.4 AUand POST 9.1 +/- 2.1 AU; CHOC PRE 8.11 +/- 4.94 AU and POST 8.78 +/- 2.78 AU). Conclusion: Taurine supplementation did not improve aerobic parameters, but waseffective in increasing taurine plasma levels and decreasing oxidative stress markers,which suggests that taurine may prevent oxidative stress in triathletes |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-09-20 2018-11-26T15:45:21Z 2018-11-26T15:45:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3389/fphys.2017.00710 Frontiers In Physiology. Lausanne: Frontiers Media Sa, v. 8, 8 p., 2017. 1664-042X http://hdl.handle.net/11449/159814 10.3389/fphys.2017.00710 WOS:000411439700001 WOS000411439700001.pdf |
url |
http://dx.doi.org/10.3389/fphys.2017.00710 http://hdl.handle.net/11449/159814 |
identifier_str_mv |
Frontiers In Physiology. Lausanne: Frontiers Media Sa, v. 8, 8 p., 2017. 1664-042X 10.3389/fphys.2017.00710 WOS:000411439700001 WOS000411439700001.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Frontiers In Physiology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
8 application/pdf |
dc.publisher.none.fl_str_mv |
Frontiers Media Sa |
publisher.none.fl_str_mv |
Frontiers Media Sa |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965699798466560 |