Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides

Detalhes bibliográficos
Autor(a) principal: Pagotto, Leonardo Libardi
Data de Publicação: 2021
Outros Autores: Spinola, Manuela Da Silva [UNESP], Nóbrega, Diego Figueiredo, Cury, Jaime Aparecido, Tenuta, Livia Maria Andaló
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1159/000515115
http://hdl.handle.net/11449/206135
Resumo: Extracellular polysaccharides (EPS), mainly the insoluble ones, increase the cariogenicity of dental biofilm, but whether they interfere with the binding and retention of fluoride is unknown. EPS-rich (EPS+) and EPS-poor (EPS-) pellets of Streptococcus mutans were formed and treated with increasing fluoride concentrations (0, 0.1, 1, or 10 mM). A concentration-dependent fluoride binding was observed in both EPS-and EPS+ pellets, but the presence of EPS did not affect the retention of fluoride in the pellets. In conclusion, the data suggest that a matrix of dental biofilm rich in EPS does not affect fluoride retention in the biofilm.
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spelling Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular PolysaccharidesExtracellular polysaccharides (EPS), mainly the insoluble ones, increase the cariogenicity of dental biofilm, but whether they interfere with the binding and retention of fluoride is unknown. EPS-rich (EPS+) and EPS-poor (EPS-) pellets of Streptococcus mutans were formed and treated with increasing fluoride concentrations (0, 0.1, 1, or 10 mM). A concentration-dependent fluoride binding was observed in both EPS-and EPS+ pellets, but the presence of EPS did not affect the retention of fluoride in the pellets. In conclusion, the data suggest that a matrix of dental biofilm rich in EPS does not affect fluoride retention in the biofilm.Department of Biosciences Piracicaba Dental School University of CampinasDepartment of Restorative Dentistry Institute of Science and Technology UnespProfessional Masters Research in Health Cesmac University CenterDepartment of Cariology Restorative Sciences and Endodontics University of MichiganDepartment of Restorative Dentistry Institute of Science and Technology UnespUniversidade Estadual de Campinas (UNICAMP)Universidade Estadual Paulista (Unesp)Cesmac University CenterUniversity of MichiganPagotto, Leonardo LibardiSpinola, Manuela Da Silva [UNESP]Nóbrega, Diego FigueiredoCury, Jaime AparecidoTenuta, Livia Maria Andaló2021-06-25T10:27:05Z2021-06-25T10:27:05Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1159/000515115Caries Research.1421-976X0008-6568http://hdl.handle.net/11449/20613510.1159/0005151152-s2.0-85103569522Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCaries Researchinfo:eu-repo/semantics/openAccess2021-10-22T21:09:49Zoai:repositorio.unesp.br:11449/206135Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-22T21:09:49Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides
title Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides
spellingShingle Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides
Pagotto, Leonardo Libardi
title_short Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides
title_full Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides
title_fullStr Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides
title_full_unstemmed Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides
title_sort Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides
author Pagotto, Leonardo Libardi
author_facet Pagotto, Leonardo Libardi
Spinola, Manuela Da Silva [UNESP]
Nóbrega, Diego Figueiredo
Cury, Jaime Aparecido
Tenuta, Livia Maria Andaló
author_role author
author2 Spinola, Manuela Da Silva [UNESP]
Nóbrega, Diego Figueiredo
Cury, Jaime Aparecido
Tenuta, Livia Maria Andaló
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual Paulista (Unesp)
Cesmac University Center
University of Michigan
dc.contributor.author.fl_str_mv Pagotto, Leonardo Libardi
Spinola, Manuela Da Silva [UNESP]
Nóbrega, Diego Figueiredo
Cury, Jaime Aparecido
Tenuta, Livia Maria Andaló
description Extracellular polysaccharides (EPS), mainly the insoluble ones, increase the cariogenicity of dental biofilm, but whether they interfere with the binding and retention of fluoride is unknown. EPS-rich (EPS+) and EPS-poor (EPS-) pellets of Streptococcus mutans were formed and treated with increasing fluoride concentrations (0, 0.1, 1, or 10 mM). A concentration-dependent fluoride binding was observed in both EPS-and EPS+ pellets, but the presence of EPS did not affect the retention of fluoride in the pellets. In conclusion, the data suggest that a matrix of dental biofilm rich in EPS does not affect fluoride retention in the biofilm.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-25T10:27:05Z
2021-06-25T10:27:05Z
2021-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1159/000515115
Caries Research.
1421-976X
0008-6568
http://hdl.handle.net/11449/206135
10.1159/000515115
2-s2.0-85103569522
url http://dx.doi.org/10.1159/000515115
http://hdl.handle.net/11449/206135
identifier_str_mv Caries Research.
1421-976X
0008-6568
10.1159/000515115
2-s2.0-85103569522
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Caries Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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