Non-contact specular microscopy in aphakic and pseudophakic dogs

Detalhes bibliográficos
Autor(a) principal: Nagatsuyu, Claudia Emi [UNESP]
Data de Publicação: 2014
Outros Autores: Abreu, Priscila Barreto De [UNESP], Kobashigawa, Karina Kamachi [UNESP], Conceição, Luciano Fernandes Da [UNESP], Morales, Adriana [UNESP], Andrade, Alexandre Lima De [UNESP], Padua, Ivan Ricardo Martinez [UNESP], Martins, Bianca Da Costa, Laus, José Luiz [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0103-84782014000400018
http://hdl.handle.net/11449/109916
Resumo: Cataract is one of the most common ocular diseases in dogs, and phacoemulsification is considered its treatment of choice. Posterior capsular opacity (PCO) is a frequent complication and may occur weeks or months after the surgery. It is known that intraocular lenses (IOL) used for the correction of post-operative hypermetropia are an adjunctive aid in the prevention of PCOs, mainly the foldable acrylics designs with square and truncated edges. However, IOL placement may result in endothelial cell loss. This study evaluated the morphology and cellularity of the endothelium by non-contact specular microscopy in aphakic and pseudophakic dogs. Endothelial cell density, endothelial cell area, coefficient of variation and hexagonal cells percent were analyzed for each group and between groups. During all evaluation periods, endothelial cell density did not alter in any group. From days 7 to 30, endothelial cell density was higher in pseudophakic dogs. However, values returned to normal and, by the end of the study, no significant difference was observed. Cell area and variation coefficient did not differ in each group or between groups. Hexagonal cells percent significantly reduced after phacoemulsification in both groups. With time, this condition returned to initial values. When both groups were compared, hexagonal cells percent were decreased in the pseudophakic group, immediately after the surgeries.
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spelling Non-contact specular microscopy in aphakic and pseudophakic dogsMicroscopia especular de não contato em cães afácicos e em pseudofácicosDogintraocular lenscorneal endotheliumSpecular microscopyCãolente intraocularendotélio cornealMicroscopia especularCataract is one of the most common ocular diseases in dogs, and phacoemulsification is considered its treatment of choice. Posterior capsular opacity (PCO) is a frequent complication and may occur weeks or months after the surgery. It is known that intraocular lenses (IOL) used for the correction of post-operative hypermetropia are an adjunctive aid in the prevention of PCOs, mainly the foldable acrylics designs with square and truncated edges. However, IOL placement may result in endothelial cell loss. This study evaluated the morphology and cellularity of the endothelium by non-contact specular microscopy in aphakic and pseudophakic dogs. Endothelial cell density, endothelial cell area, coefficient of variation and hexagonal cells percent were analyzed for each group and between groups. During all evaluation periods, endothelial cell density did not alter in any group. From days 7 to 30, endothelial cell density was higher in pseudophakic dogs. However, values returned to normal and, by the end of the study, no significant difference was observed. Cell area and variation coefficient did not differ in each group or between groups. Hexagonal cells percent significantly reduced after phacoemulsification in both groups. With time, this condition returned to initial values. When both groups were compared, hexagonal cells percent were decreased in the pseudophakic group, immediately after the surgeries.A catarata está entre as afecções oculares mais frequentes em cães, sendo a facoemulsificação o método que melhor se adequa à sua terapia. A opacidade de cápsula posterior (OCP) encontra-se entre as complicações mais comuns e se manifesta em semanas ou meses após a facectomia. Lentes intraoculares, empregadas na correção da hipermetropia pós-cirúrgica, contribuem para a prevenção das OCPs, especialmente as acrílicas dobráveis, com bordas truncadas ou quadradas. Entretanto, a sua implantação pode resultar na perda de células endoteliais. Com a pesquisa, propuseram-se avaliar a morfologia e a celularidade endoteliais, a microscopia especular de não contato, em pacientes afácicos e em pseudofácicos. Foram analisados a densidade celular, a área celular, o coeficiente de variação e o percentual de células hexagonais inter e entre os grupos. Ao longo dos momentos da avaliação, a densidade das células endoteliais não se alterou significativamente dentro dos grupos. Na comparação entre os grupos, ela foi maior nos pseudofácicos, em períodos que variaram de 7 a 30 dias, entretanto retornaram a valores próximos aos iniciais, tornando a diferença entre os dois grupos não significativa ao final da avaliação. Relativamente à área celular e ao coeficiente de variação, não houve diferença significativa, inter e entre os grupos. Houve diferença dentro dos grupos relativamente à hexagonalidade, com diminuição percentual após a facoemulsificação. As condições retornaram ao basal. Na comparação entre pacientes pseudofácicos e afácicos, houve diminuição nos pseudofácicos imediatamente à cirurgia.National Counsel of Technological and Scientific DevelopmentBrazilian Federal Agency for Support and Evaluation of Graduate EducationFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Estadual Paulista (UNESP) Faculdade de Ciências Agrárias e Veterinárias (FCAV) Departamento de Clínica e Cirurgia VeterináriaUniversidade Estadual Paulista (UNESP) Faculdade de Medicina Veterinária de Araçatuba (FMVA) Departamento de ClínicaUniversity of Florida (UFL) Departments of Small and Large Animal Clinical SciencesUniversidade Estadual Paulista (UNESP) Faculdade de Ciências Agrárias e Veterinárias (FCAV) Departamento de Clínica e Cirurgia VeterináriaUniversidade Estadual Paulista (UNESP) Faculdade de Medicina Veterinária de Araçatuba (FMVA) Departamento de ClínicaFAPESP: 09/51773-4FAPESP: 10/18605-8National Counsel of Technological and Scientific Development300833/2010-5Universidade Federal de Santa MariaUniversidade Estadual Paulista (Unesp)University of Florida (UFL) Departments of Small and Large Animal Clinical SciencesNagatsuyu, Claudia Emi [UNESP]Abreu, Priscila Barreto De [UNESP]Kobashigawa, Karina Kamachi [UNESP]Conceição, Luciano Fernandes Da [UNESP]Morales, Adriana [UNESP]Andrade, Alexandre Lima De [UNESP]Padua, Ivan Ricardo Martinez [UNESP]Martins, Bianca Da CostaLaus, José Luiz [UNESP]2014-10-01T13:08:40Z2014-10-01T13:08:40Z2014-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article682-687application/pdfhttp://dx.doi.org/10.1590/S0103-84782014000400018Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 4, p. 682-687, 2014.0103-8478http://hdl.handle.net/11449/10991610.1590/S0103-84782014000400018S0103-84782014000400018WOS:000334281000018S0103-84782014000400018.pdf47861991737327930000-0001-8967-0753SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiência Rural0.5250,337info:eu-repo/semantics/openAccess2023-11-05T06:07:55Zoai:repositorio.unesp.br:11449/109916Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-11-05T06:07:55Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Non-contact specular microscopy in aphakic and pseudophakic dogs
Microscopia especular de não contato em cães afácicos e em pseudofácicos
title Non-contact specular microscopy in aphakic and pseudophakic dogs
spellingShingle Non-contact specular microscopy in aphakic and pseudophakic dogs
Nagatsuyu, Claudia Emi [UNESP]
Dog
intraocular lens
corneal endothelium
Specular microscopy
Cão
lente intraocular
endotélio corneal
Microscopia especular
title_short Non-contact specular microscopy in aphakic and pseudophakic dogs
title_full Non-contact specular microscopy in aphakic and pseudophakic dogs
title_fullStr Non-contact specular microscopy in aphakic and pseudophakic dogs
title_full_unstemmed Non-contact specular microscopy in aphakic and pseudophakic dogs
title_sort Non-contact specular microscopy in aphakic and pseudophakic dogs
author Nagatsuyu, Claudia Emi [UNESP]
author_facet Nagatsuyu, Claudia Emi [UNESP]
Abreu, Priscila Barreto De [UNESP]
Kobashigawa, Karina Kamachi [UNESP]
Conceição, Luciano Fernandes Da [UNESP]
Morales, Adriana [UNESP]
Andrade, Alexandre Lima De [UNESP]
Padua, Ivan Ricardo Martinez [UNESP]
Martins, Bianca Da Costa
Laus, José Luiz [UNESP]
author_role author
author2 Abreu, Priscila Barreto De [UNESP]
Kobashigawa, Karina Kamachi [UNESP]
Conceição, Luciano Fernandes Da [UNESP]
Morales, Adriana [UNESP]
Andrade, Alexandre Lima De [UNESP]
Padua, Ivan Ricardo Martinez [UNESP]
Martins, Bianca Da Costa
Laus, José Luiz [UNESP]
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
University of Florida (UFL) Departments of Small and Large Animal Clinical Sciences
dc.contributor.author.fl_str_mv Nagatsuyu, Claudia Emi [UNESP]
Abreu, Priscila Barreto De [UNESP]
Kobashigawa, Karina Kamachi [UNESP]
Conceição, Luciano Fernandes Da [UNESP]
Morales, Adriana [UNESP]
Andrade, Alexandre Lima De [UNESP]
Padua, Ivan Ricardo Martinez [UNESP]
Martins, Bianca Da Costa
Laus, José Luiz [UNESP]
dc.subject.por.fl_str_mv Dog
intraocular lens
corneal endothelium
Specular microscopy
Cão
lente intraocular
endotélio corneal
Microscopia especular
topic Dog
intraocular lens
corneal endothelium
Specular microscopy
Cão
lente intraocular
endotélio corneal
Microscopia especular
description Cataract is one of the most common ocular diseases in dogs, and phacoemulsification is considered its treatment of choice. Posterior capsular opacity (PCO) is a frequent complication and may occur weeks or months after the surgery. It is known that intraocular lenses (IOL) used for the correction of post-operative hypermetropia are an adjunctive aid in the prevention of PCOs, mainly the foldable acrylics designs with square and truncated edges. However, IOL placement may result in endothelial cell loss. This study evaluated the morphology and cellularity of the endothelium by non-contact specular microscopy in aphakic and pseudophakic dogs. Endothelial cell density, endothelial cell area, coefficient of variation and hexagonal cells percent were analyzed for each group and between groups. During all evaluation periods, endothelial cell density did not alter in any group. From days 7 to 30, endothelial cell density was higher in pseudophakic dogs. However, values returned to normal and, by the end of the study, no significant difference was observed. Cell area and variation coefficient did not differ in each group or between groups. Hexagonal cells percent significantly reduced after phacoemulsification in both groups. With time, this condition returned to initial values. When both groups were compared, hexagonal cells percent were decreased in the pseudophakic group, immediately after the surgeries.
publishDate 2014
dc.date.none.fl_str_mv 2014-10-01T13:08:40Z
2014-10-01T13:08:40Z
2014-04-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0103-84782014000400018
Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 4, p. 682-687, 2014.
0103-8478
http://hdl.handle.net/11449/109916
10.1590/S0103-84782014000400018
S0103-84782014000400018
WOS:000334281000018
S0103-84782014000400018.pdf
4786199173732793
0000-0001-8967-0753
url http://dx.doi.org/10.1590/S0103-84782014000400018
http://hdl.handle.net/11449/109916
identifier_str_mv Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 4, p. 682-687, 2014.
0103-8478
10.1590/S0103-84782014000400018
S0103-84782014000400018
WOS:000334281000018
S0103-84782014000400018.pdf
4786199173732793
0000-0001-8967-0753
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ciência Rural
0.525
0,337
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 682-687
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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