Non-contact specular microscopy in aphakic and pseudophakic dogs
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0103-84782014000400018 http://hdl.handle.net/11449/109916 |
Resumo: | Cataract is one of the most common ocular diseases in dogs, and phacoemulsification is considered its treatment of choice. Posterior capsular opacity (PCO) is a frequent complication and may occur weeks or months after the surgery. It is known that intraocular lenses (IOL) used for the correction of post-operative hypermetropia are an adjunctive aid in the prevention of PCOs, mainly the foldable acrylics designs with square and truncated edges. However, IOL placement may result in endothelial cell loss. This study evaluated the morphology and cellularity of the endothelium by non-contact specular microscopy in aphakic and pseudophakic dogs. Endothelial cell density, endothelial cell area, coefficient of variation and hexagonal cells percent were analyzed for each group and between groups. During all evaluation periods, endothelial cell density did not alter in any group. From days 7 to 30, endothelial cell density was higher in pseudophakic dogs. However, values returned to normal and, by the end of the study, no significant difference was observed. Cell area and variation coefficient did not differ in each group or between groups. Hexagonal cells percent significantly reduced after phacoemulsification in both groups. With time, this condition returned to initial values. When both groups were compared, hexagonal cells percent were decreased in the pseudophakic group, immediately after the surgeries. |
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Non-contact specular microscopy in aphakic and pseudophakic dogsMicroscopia especular de não contato em cães afácicos e em pseudofácicosDogintraocular lenscorneal endotheliumSpecular microscopyCãolente intraocularendotélio cornealMicroscopia especularCataract is one of the most common ocular diseases in dogs, and phacoemulsification is considered its treatment of choice. Posterior capsular opacity (PCO) is a frequent complication and may occur weeks or months after the surgery. It is known that intraocular lenses (IOL) used for the correction of post-operative hypermetropia are an adjunctive aid in the prevention of PCOs, mainly the foldable acrylics designs with square and truncated edges. However, IOL placement may result in endothelial cell loss. This study evaluated the morphology and cellularity of the endothelium by non-contact specular microscopy in aphakic and pseudophakic dogs. Endothelial cell density, endothelial cell area, coefficient of variation and hexagonal cells percent were analyzed for each group and between groups. During all evaluation periods, endothelial cell density did not alter in any group. From days 7 to 30, endothelial cell density was higher in pseudophakic dogs. However, values returned to normal and, by the end of the study, no significant difference was observed. Cell area and variation coefficient did not differ in each group or between groups. Hexagonal cells percent significantly reduced after phacoemulsification in both groups. With time, this condition returned to initial values. When both groups were compared, hexagonal cells percent were decreased in the pseudophakic group, immediately after the surgeries.A catarata está entre as afecções oculares mais frequentes em cães, sendo a facoemulsificação o método que melhor se adequa à sua terapia. A opacidade de cápsula posterior (OCP) encontra-se entre as complicações mais comuns e se manifesta em semanas ou meses após a facectomia. Lentes intraoculares, empregadas na correção da hipermetropia pós-cirúrgica, contribuem para a prevenção das OCPs, especialmente as acrílicas dobráveis, com bordas truncadas ou quadradas. Entretanto, a sua implantação pode resultar na perda de células endoteliais. Com a pesquisa, propuseram-se avaliar a morfologia e a celularidade endoteliais, a microscopia especular de não contato, em pacientes afácicos e em pseudofácicos. Foram analisados a densidade celular, a área celular, o coeficiente de variação e o percentual de células hexagonais inter e entre os grupos. Ao longo dos momentos da avaliação, a densidade das células endoteliais não se alterou significativamente dentro dos grupos. Na comparação entre os grupos, ela foi maior nos pseudofácicos, em períodos que variaram de 7 a 30 dias, entretanto retornaram a valores próximos aos iniciais, tornando a diferença entre os dois grupos não significativa ao final da avaliação. Relativamente à área celular e ao coeficiente de variação, não houve diferença significativa, inter e entre os grupos. Houve diferença dentro dos grupos relativamente à hexagonalidade, com diminuição percentual após a facoemulsificação. As condições retornaram ao basal. Na comparação entre pacientes pseudofácicos e afácicos, houve diminuição nos pseudofácicos imediatamente à cirurgia.National Counsel of Technological and Scientific DevelopmentBrazilian Federal Agency for Support and Evaluation of Graduate EducationFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Estadual Paulista (UNESP) Faculdade de Ciências Agrárias e Veterinárias (FCAV) Departamento de Clínica e Cirurgia VeterináriaUniversidade Estadual Paulista (UNESP) Faculdade de Medicina Veterinária de Araçatuba (FMVA) Departamento de ClínicaUniversity of Florida (UFL) Departments of Small and Large Animal Clinical SciencesUniversidade Estadual Paulista (UNESP) Faculdade de Ciências Agrárias e Veterinárias (FCAV) Departamento de Clínica e Cirurgia VeterináriaUniversidade Estadual Paulista (UNESP) Faculdade de Medicina Veterinária de Araçatuba (FMVA) Departamento de ClínicaFAPESP: 09/51773-4FAPESP: 10/18605-8National Counsel of Technological and Scientific Development300833/2010-5Universidade Federal de Santa MariaUniversidade Estadual Paulista (Unesp)University of Florida (UFL) Departments of Small and Large Animal Clinical SciencesNagatsuyu, Claudia Emi [UNESP]Abreu, Priscila Barreto De [UNESP]Kobashigawa, Karina Kamachi [UNESP]Conceição, Luciano Fernandes Da [UNESP]Morales, Adriana [UNESP]Andrade, Alexandre Lima De [UNESP]Padua, Ivan Ricardo Martinez [UNESP]Martins, Bianca Da CostaLaus, José Luiz [UNESP]2014-10-01T13:08:40Z2014-10-01T13:08:40Z2014-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article682-687application/pdfhttp://dx.doi.org/10.1590/S0103-84782014000400018Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 4, p. 682-687, 2014.0103-8478http://hdl.handle.net/11449/10991610.1590/S0103-84782014000400018S0103-84782014000400018WOS:000334281000018S0103-84782014000400018.pdf47861991737327930000-0001-8967-0753SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiência Rural0.5250,337info:eu-repo/semantics/openAccess2024-06-06T14:09:27Zoai:repositorio.unesp.br:11449/109916Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:57:27.335324Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Non-contact specular microscopy in aphakic and pseudophakic dogs Microscopia especular de não contato em cães afácicos e em pseudofácicos |
title |
Non-contact specular microscopy in aphakic and pseudophakic dogs |
spellingShingle |
Non-contact specular microscopy in aphakic and pseudophakic dogs Nagatsuyu, Claudia Emi [UNESP] Dog intraocular lens corneal endothelium Specular microscopy Cão lente intraocular endotélio corneal Microscopia especular |
title_short |
Non-contact specular microscopy in aphakic and pseudophakic dogs |
title_full |
Non-contact specular microscopy in aphakic and pseudophakic dogs |
title_fullStr |
Non-contact specular microscopy in aphakic and pseudophakic dogs |
title_full_unstemmed |
Non-contact specular microscopy in aphakic and pseudophakic dogs |
title_sort |
Non-contact specular microscopy in aphakic and pseudophakic dogs |
author |
Nagatsuyu, Claudia Emi [UNESP] |
author_facet |
Nagatsuyu, Claudia Emi [UNESP] Abreu, Priscila Barreto De [UNESP] Kobashigawa, Karina Kamachi [UNESP] Conceição, Luciano Fernandes Da [UNESP] Morales, Adriana [UNESP] Andrade, Alexandre Lima De [UNESP] Padua, Ivan Ricardo Martinez [UNESP] Martins, Bianca Da Costa Laus, José Luiz [UNESP] |
author_role |
author |
author2 |
Abreu, Priscila Barreto De [UNESP] Kobashigawa, Karina Kamachi [UNESP] Conceição, Luciano Fernandes Da [UNESP] Morales, Adriana [UNESP] Andrade, Alexandre Lima De [UNESP] Padua, Ivan Ricardo Martinez [UNESP] Martins, Bianca Da Costa Laus, José Luiz [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) University of Florida (UFL) Departments of Small and Large Animal Clinical Sciences |
dc.contributor.author.fl_str_mv |
Nagatsuyu, Claudia Emi [UNESP] Abreu, Priscila Barreto De [UNESP] Kobashigawa, Karina Kamachi [UNESP] Conceição, Luciano Fernandes Da [UNESP] Morales, Adriana [UNESP] Andrade, Alexandre Lima De [UNESP] Padua, Ivan Ricardo Martinez [UNESP] Martins, Bianca Da Costa Laus, José Luiz [UNESP] |
dc.subject.por.fl_str_mv |
Dog intraocular lens corneal endothelium Specular microscopy Cão lente intraocular endotélio corneal Microscopia especular |
topic |
Dog intraocular lens corneal endothelium Specular microscopy Cão lente intraocular endotélio corneal Microscopia especular |
description |
Cataract is one of the most common ocular diseases in dogs, and phacoemulsification is considered its treatment of choice. Posterior capsular opacity (PCO) is a frequent complication and may occur weeks or months after the surgery. It is known that intraocular lenses (IOL) used for the correction of post-operative hypermetropia are an adjunctive aid in the prevention of PCOs, mainly the foldable acrylics designs with square and truncated edges. However, IOL placement may result in endothelial cell loss. This study evaluated the morphology and cellularity of the endothelium by non-contact specular microscopy in aphakic and pseudophakic dogs. Endothelial cell density, endothelial cell area, coefficient of variation and hexagonal cells percent were analyzed for each group and between groups. During all evaluation periods, endothelial cell density did not alter in any group. From days 7 to 30, endothelial cell density was higher in pseudophakic dogs. However, values returned to normal and, by the end of the study, no significant difference was observed. Cell area and variation coefficient did not differ in each group or between groups. Hexagonal cells percent significantly reduced after phacoemulsification in both groups. With time, this condition returned to initial values. When both groups were compared, hexagonal cells percent were decreased in the pseudophakic group, immediately after the surgeries. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-10-01T13:08:40Z 2014-10-01T13:08:40Z 2014-04-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0103-84782014000400018 Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 4, p. 682-687, 2014. 0103-8478 http://hdl.handle.net/11449/109916 10.1590/S0103-84782014000400018 S0103-84782014000400018 WOS:000334281000018 S0103-84782014000400018.pdf 4786199173732793 0000-0001-8967-0753 |
url |
http://dx.doi.org/10.1590/S0103-84782014000400018 http://hdl.handle.net/11449/109916 |
identifier_str_mv |
Ciência Rural. Universidade Federal de Santa Maria, v. 44, n. 4, p. 682-687, 2014. 0103-8478 10.1590/S0103-84782014000400018 S0103-84782014000400018 WOS:000334281000018 S0103-84782014000400018.pdf 4786199173732793 0000-0001-8967-0753 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ciência Rural 0.525 0,337 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
682-687 application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128726676799488 |