Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes

Detalhes bibliográficos
Autor(a) principal: de Freitas, Ana Cláudia [UNESP]
Data de Publicação: 2016
Outros Autores: de Camargo, Gregório Miguel Ferreira, Stafuzza, Nedenia Bonvino [UNESP], Aspilcueta-Borquis, Rusbel Raul, Venturini, Guilherme Costa [UNESP], Dias, Marina Mortati [UNESP], Cardoso, Diercles Francisco [UNESP], Tonhati, Humberto [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/s11250-016-1110-x
http://hdl.handle.net/11449/173321
Resumo: This study identified polymorphisms in the DGAT1 gene in Murrah buffaloes and investigated the associations to milk production and quality traits (milk, fat and protein yields and percentages, somatic cell count). Genomic DNA was extracted from hair follicles collected from the tail of 196 females. Three SNPs were identified in DGAT1 gene by sequencing. Statistical analyses were performed to verify the linkage and the association between polymorphisms and traits. The estimated value of r2 between two SNPs in exon 17 (g.11,783G > A and g.11,785 T > C) was 0.029. SNP g.11,785 T > C was significantly associated (P < 0.05) to fat and protein percentage. Dominance effect was significant for milk and fat yields and protein percentage (P < 0.05). The additive effect of the SNP g.11,785 T > C was significant for protein production and somatic cell count (P < 0.05). It indicates that assisted marker selection might be done with considerations to balance production and udder health.
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spelling Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloesBubalus bubalisDiacylglycerol O-acyltransferase1Fat percentagePolymorphismProtein percentageThis study identified polymorphisms in the DGAT1 gene in Murrah buffaloes and investigated the associations to milk production and quality traits (milk, fat and protein yields and percentages, somatic cell count). Genomic DNA was extracted from hair follicles collected from the tail of 196 females. Three SNPs were identified in DGAT1 gene by sequencing. Statistical analyses were performed to verify the linkage and the association between polymorphisms and traits. The estimated value of r2 between two SNPs in exon 17 (g.11,783G > A and g.11,785 T > C) was 0.029. SNP g.11,785 T > C was significantly associated (P < 0.05) to fat and protein percentage. Dominance effect was significant for milk and fat yields and protein percentage (P < 0.05). The additive effect of the SNP g.11,785 T > C was significant for protein production and somatic cell count (P < 0.05). It indicates that assisted marker selection might be done with considerations to balance production and udder health.Departamento de Zootecnia Faculdade de Ciências Agrárias e Veterinárias (FCAV) Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp), Via de Acesso Prof. Paulo Donato Castellane s/nUniversidade Tecnológica Federal do Paraná (UTFPR), Estrada para Boa Esperança, km 04Departamento de Ciências Exatas Faculdade de Ciências Agrárias e Veterinárias (FCAV) Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp), Via de Acesso Prof. Paulo Donato Castellane s/nFaculdade de Ciências Agrárias (FCA) Universidade Federal da Grande Dourados (UFGD), Rodovia Dourados a Itahum km 12Departamento de Zootecnia Faculdade de Ciências Agrárias e Veterinárias (FCAV) Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp), Via de Acesso Prof. Paulo Donato Castellane s/nDepartamento de Ciências Exatas Faculdade de Ciências Agrárias e Veterinárias (FCAV) Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp), Via de Acesso Prof. Paulo Donato Castellane s/nUniversidade Estadual Paulista (Unesp)Universidade Tecnológica Federal do Paraná (UTFPR)Universidade Federal da Grande Dourados (UFGD)de Freitas, Ana Cláudia [UNESP]de Camargo, Gregório Miguel FerreiraStafuzza, Nedenia Bonvino [UNESP]Aspilcueta-Borquis, Rusbel RaulVenturini, Guilherme Costa [UNESP]Dias, Marina Mortati [UNESP]Cardoso, Diercles Francisco [UNESP]Tonhati, Humberto [UNESP]2018-12-11T17:04:39Z2018-12-11T17:04:39Z2016-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1421-1426application/pdfhttp://dx.doi.org/10.1007/s11250-016-1110-xTropical Animal Health and Production, v. 48, n. 7, p. 1421-1426, 2016.1573-74380049-4747http://hdl.handle.net/11449/17332110.1007/s11250-016-1110-x2-s2.0-849800117172-s2.0-84980011717.pdf2-s2.0-84980011717.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTropical Animal Health and Production0,5110,511info:eu-repo/semantics/openAccess2024-06-07T18:41:31Zoai:repositorio.unesp.br:11449/173321Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-06-07T18:41:31Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes
title Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes
spellingShingle Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes
de Freitas, Ana Cláudia [UNESP]
Bubalus bubalis
Diacylglycerol O-acyltransferase1
Fat percentage
Polymorphism
Protein percentage
title_short Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes
title_full Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes
title_fullStr Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes
title_full_unstemmed Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes
title_sort Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes
author de Freitas, Ana Cláudia [UNESP]
author_facet de Freitas, Ana Cláudia [UNESP]
de Camargo, Gregório Miguel Ferreira
Stafuzza, Nedenia Bonvino [UNESP]
Aspilcueta-Borquis, Rusbel Raul
Venturini, Guilherme Costa [UNESP]
Dias, Marina Mortati [UNESP]
Cardoso, Diercles Francisco [UNESP]
Tonhati, Humberto [UNESP]
author_role author
author2 de Camargo, Gregório Miguel Ferreira
Stafuzza, Nedenia Bonvino [UNESP]
Aspilcueta-Borquis, Rusbel Raul
Venturini, Guilherme Costa [UNESP]
Dias, Marina Mortati [UNESP]
Cardoso, Diercles Francisco [UNESP]
Tonhati, Humberto [UNESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Tecnológica Federal do Paraná (UTFPR)
Universidade Federal da Grande Dourados (UFGD)
dc.contributor.author.fl_str_mv de Freitas, Ana Cláudia [UNESP]
de Camargo, Gregório Miguel Ferreira
Stafuzza, Nedenia Bonvino [UNESP]
Aspilcueta-Borquis, Rusbel Raul
Venturini, Guilherme Costa [UNESP]
Dias, Marina Mortati [UNESP]
Cardoso, Diercles Francisco [UNESP]
Tonhati, Humberto [UNESP]
dc.subject.por.fl_str_mv Bubalus bubalis
Diacylglycerol O-acyltransferase1
Fat percentage
Polymorphism
Protein percentage
topic Bubalus bubalis
Diacylglycerol O-acyltransferase1
Fat percentage
Polymorphism
Protein percentage
description This study identified polymorphisms in the DGAT1 gene in Murrah buffaloes and investigated the associations to milk production and quality traits (milk, fat and protein yields and percentages, somatic cell count). Genomic DNA was extracted from hair follicles collected from the tail of 196 females. Three SNPs were identified in DGAT1 gene by sequencing. Statistical analyses were performed to verify the linkage and the association between polymorphisms and traits. The estimated value of r2 between two SNPs in exon 17 (g.11,783G > A and g.11,785 T > C) was 0.029. SNP g.11,785 T > C was significantly associated (P < 0.05) to fat and protein percentage. Dominance effect was significant for milk and fat yields and protein percentage (P < 0.05). The additive effect of the SNP g.11,785 T > C was significant for protein production and somatic cell count (P < 0.05). It indicates that assisted marker selection might be done with considerations to balance production and udder health.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
2018-12-11T17:04:39Z
2018-12-11T17:04:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/s11250-016-1110-x
Tropical Animal Health and Production, v. 48, n. 7, p. 1421-1426, 2016.
1573-7438
0049-4747
http://hdl.handle.net/11449/173321
10.1007/s11250-016-1110-x
2-s2.0-84980011717
2-s2.0-84980011717.pdf
2-s2.0-84980011717.pdf
url http://dx.doi.org/10.1007/s11250-016-1110-x
http://hdl.handle.net/11449/173321
identifier_str_mv Tropical Animal Health and Production, v. 48, n. 7, p. 1421-1426, 2016.
1573-7438
0049-4747
10.1007/s11250-016-1110-x
2-s2.0-84980011717
2-s2.0-84980011717.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Tropical Animal Health and Production
0,511
0,511
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1421-1426
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1803045355000954880

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