Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/220296 |
Resumo: | Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent complications associated with excess adiposity and has been identified as the leading cause of liver disease in pediatric populations worldwide. Because cardiorespiratory fitness (CRF) is related to physical activity (PA) levels, and increased PA plays a protective role against NAFLD risk factors, the aim of this study was to analyze the association between PA and a fatty liver marker (alanine aminotransferase - ALT) in obese children and adolescents, independently of central adiposity or CRF. 131 obese children (83 girls, 7-15 year-olds) involved in a PA promotion program comprised the sample. Measurements included anthropometric and body composition evaluations (DEXA), biological measurements (venipuncture), CRF (progressive treadmill test), PA (accelerometry), and maturational stage (Tanner criteria). The associations between ALT with PA intensities, central obesity, and CRF were calculated by three different models of linear regression, adjusted for potential confounders. Level of significance was set at 95%. RESULTS: ALT was negatively associated with MVPA (β = -0.305), and CRF (β = - 0.426), and positively associated with central obesity (β=.468). After adjustment for central obesity the negative and statistically significant association between ALT with MVPA (β = -0.364) and CRF (β = -0.550) still persists while a positive and significantly correlation was shown between ALT and SB (β = 0.382). Additional adjustment for CRF (Model 3) showed significant associations for all the PA intensities analyzed including light activity. PA at different intensities is associated to a fatty liver marker in obese children and adolescents, independently of central adiposity or CRF. |
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Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitnessCardiorespiratory fitnessCentral obesityFatty liverObese youthPhysical activityNonalcoholic fatty liver disease (NAFLD) is one of the most frequent complications associated with excess adiposity and has been identified as the leading cause of liver disease in pediatric populations worldwide. Because cardiorespiratory fitness (CRF) is related to physical activity (PA) levels, and increased PA plays a protective role against NAFLD risk factors, the aim of this study was to analyze the association between PA and a fatty liver marker (alanine aminotransferase - ALT) in obese children and adolescents, independently of central adiposity or CRF. 131 obese children (83 girls, 7-15 year-olds) involved in a PA promotion program comprised the sample. Measurements included anthropometric and body composition evaluations (DEXA), biological measurements (venipuncture), CRF (progressive treadmill test), PA (accelerometry), and maturational stage (Tanner criteria). The associations between ALT with PA intensities, central obesity, and CRF were calculated by three different models of linear regression, adjusted for potential confounders. Level of significance was set at 95%. RESULTS: ALT was negatively associated with MVPA (β = -0.305), and CRF (β = - 0.426), and positively associated with central obesity (β=.468). After adjustment for central obesity the negative and statistically significant association between ALT with MVPA (β = -0.364) and CRF (β = -0.550) still persists while a positive and significantly correlation was shown between ALT and SB (β = 0.382). Additional adjustment for CRF (Model 3) showed significant associations for all the PA intensities analyzed including light activity. PA at different intensities is associated to a fatty liver marker in obese children and adolescents, independently of central adiposity or CRF.Research Centre in Physical Activity Health and Leisure Porto UniversityFederal Rural University of PernambucoResearch Centre of Assessment and Exercise Prescription Univ Estadual PaulistaFederal University of ParaibaUniversity Institute of MaiaResearch Centre of Assessment and Exercise Prescription Univ Estadual PaulistaPorto UniversityFederal Rural University of PernambucoUniversidade Estadual Paulista (UNESP)Federal University of ParaibaUniversity Institute of MaiaMartins, ClariceAires, LuisaFreitas Júnior, Ismael [UNESP]Silva, GustavoSilva, AlexandreLemos, LuísMota, Jorge2022-04-28T19:00:39Z2022-04-28T19:00:39Z2014-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article103-109Journal of Sports Science and Medicine, v. 14, n. 1, p. 103-109, 2014.1303-2968http://hdl.handle.net/11449/2202962-s2.0-84921825824Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Sports Science and Medicineinfo:eu-repo/semantics/openAccess2022-04-28T19:00:39Zoai:repositorio.unesp.br:11449/220296Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:45:37.337078Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness |
title |
Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness |
spellingShingle |
Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness Martins, Clarice Cardiorespiratory fitness Central obesity Fatty liver Obese youth Physical activity |
title_short |
Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness |
title_full |
Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness |
title_fullStr |
Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness |
title_full_unstemmed |
Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness |
title_sort |
Physical activity is related to fatty liver marker in obese youth, independently of central obesity or cardiorespiratory fitness |
author |
Martins, Clarice |
author_facet |
Martins, Clarice Aires, Luisa Freitas Júnior, Ismael [UNESP] Silva, Gustavo Silva, Alexandre Lemos, Luís Mota, Jorge |
author_role |
author |
author2 |
Aires, Luisa Freitas Júnior, Ismael [UNESP] Silva, Gustavo Silva, Alexandre Lemos, Luís Mota, Jorge |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Porto University Federal Rural University of Pernambuco Universidade Estadual Paulista (UNESP) Federal University of Paraiba University Institute of Maia |
dc.contributor.author.fl_str_mv |
Martins, Clarice Aires, Luisa Freitas Júnior, Ismael [UNESP] Silva, Gustavo Silva, Alexandre Lemos, Luís Mota, Jorge |
dc.subject.por.fl_str_mv |
Cardiorespiratory fitness Central obesity Fatty liver Obese youth Physical activity |
topic |
Cardiorespiratory fitness Central obesity Fatty liver Obese youth Physical activity |
description |
Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent complications associated with excess adiposity and has been identified as the leading cause of liver disease in pediatric populations worldwide. Because cardiorespiratory fitness (CRF) is related to physical activity (PA) levels, and increased PA plays a protective role against NAFLD risk factors, the aim of this study was to analyze the association between PA and a fatty liver marker (alanine aminotransferase - ALT) in obese children and adolescents, independently of central adiposity or CRF. 131 obese children (83 girls, 7-15 year-olds) involved in a PA promotion program comprised the sample. Measurements included anthropometric and body composition evaluations (DEXA), biological measurements (venipuncture), CRF (progressive treadmill test), PA (accelerometry), and maturational stage (Tanner criteria). The associations between ALT with PA intensities, central obesity, and CRF were calculated by three different models of linear regression, adjusted for potential confounders. Level of significance was set at 95%. RESULTS: ALT was negatively associated with MVPA (β = -0.305), and CRF (β = - 0.426), and positively associated with central obesity (β=.468). After adjustment for central obesity the negative and statistically significant association between ALT with MVPA (β = -0.364) and CRF (β = -0.550) still persists while a positive and significantly correlation was shown between ALT and SB (β = 0.382). Additional adjustment for CRF (Model 3) showed significant associations for all the PA intensities analyzed including light activity. PA at different intensities is associated to a fatty liver marker in obese children and adolescents, independently of central adiposity or CRF. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 2022-04-28T19:00:39Z 2022-04-28T19:00:39Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Journal of Sports Science and Medicine, v. 14, n. 1, p. 103-109, 2014. 1303-2968 http://hdl.handle.net/11449/220296 2-s2.0-84921825824 |
identifier_str_mv |
Journal of Sports Science and Medicine, v. 14, n. 1, p. 103-109, 2014. 1303-2968 2-s2.0-84921825824 |
url |
http://hdl.handle.net/11449/220296 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Sports Science and Medicine |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
103-109 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129460148371456 |