Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.clnesp.2021.03.026 http://hdl.handle.net/11449/210357 |
Resumo: | Purpose: Neuromuscular electrical stimulation (NMES) elicits muscle contraction and has been shown to attenuate muscle atrophy when physical activity is not possible. Thus, we hypothesized that intradialytic NMES would attenuate the loss leg lean mass and improve the phase angle in patients undergoing hemodialysis (HD). Methods: A randomized controlled trial was performed with twenty-one adult HD patients (n = 8 F, n = 13 M; 45.8 +/- 10.6 y) randomly assigned to usual care (control group, n = 11; 4F/7M) or to the NMES group (n = 10; 4F/6M). NMES was applied bilaterally at the origin and insertion points of the quadriceps or gastrocnemius muscles for 40 min during each HD session (3x/wk for one month). Pre-and post-intervention, we measured leg lean mass using dual-energy x-ray absorptiometry and phase angle using bioelectrical impedance analysis. Results: NMES did not change leg lean mass compared to the control group. Phase angle increased in the NMES compared to the control group (Delta: +0.71 +/- 0.27 degrees vs. -0.46 +/- 0.23 degrees, p = 0.004) with interaction time x treatment (ANOVA p = 0.004). Conclusion: Short-term intradialytic NMES targeting muscles of the legs improved the phase angle but did not change leg lean mass. Brazilian registry of clinical trials under the code: RBR-98wzgn. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved. |
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Repositório Institucional da UNESP |
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Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trialHemodialysisPhase angleNMESLean body massPurpose: Neuromuscular electrical stimulation (NMES) elicits muscle contraction and has been shown to attenuate muscle atrophy when physical activity is not possible. Thus, we hypothesized that intradialytic NMES would attenuate the loss leg lean mass and improve the phase angle in patients undergoing hemodialysis (HD). Methods: A randomized controlled trial was performed with twenty-one adult HD patients (n = 8 F, n = 13 M; 45.8 +/- 10.6 y) randomly assigned to usual care (control group, n = 11; 4F/7M) or to the NMES group (n = 10; 4F/6M). NMES was applied bilaterally at the origin and insertion points of the quadriceps or gastrocnemius muscles for 40 min during each HD session (3x/wk for one month). Pre-and post-intervention, we measured leg lean mass using dual-energy x-ray absorptiometry and phase angle using bioelectrical impedance analysis. Results: NMES did not change leg lean mass compared to the control group. Phase angle increased in the NMES compared to the control group (Delta: +0.71 +/- 0.27 degrees vs. -0.46 +/- 0.23 degrees, p = 0.004) with interaction time x treatment (ANOVA p = 0.004). Conclusion: Short-term intradialytic NMES targeting muscles of the legs improved the phase angle but did not change leg lean mass. Brazilian registry of clinical trials under the code: RBR-98wzgn. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Fed Goias, Fac Nutr, Clin & Sports Nutr Res Lab Labince, Goiania, Go, BrazilSao Paulo State Univ, Dept Phys Educ, Immunometab Res Grp, Presidente Prudente, BrazilGeneva Univ Hosp, Clin Nutr, Geneva, SwitzerlandUniv Roma La Sapienza, Dept Translat & Precis Med, Rome, ItalyUniv Exeter, Coll Life & Environm Sci, Dept Sport & Hlth Sci, Exeter, Devon, EnglandSao Paulo State Univ, Dept Phys Educ, Immunometab Res Grp, Presidente Prudente, BrazilCNPq: 312252/2019-6Elsevier B.V.Universidade Federal de Goiás (UFG)Universidade Estadual Paulista (Unesp)Geneva Univ HospUniv Roma La SapienzaUniv ExeterMarini, Ana Clara B.Motobu, Reika D.Freitas, Ana TvsMota, Joao F.Monteiro, Paula A. [UNESP]Pichard, ClaudeLaviano, AlessandroWall, Benjamin T.Pimentel, Gustavo D.2021-06-25T15:05:58Z2021-06-25T15:05:58Z2021-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article111-116http://dx.doi.org/10.1016/j.clnesp.2021.03.026Clinical Nutrition Espen. Amsterdam: Elsevier, v. 43, p. 111-116, 2021.2405-4577http://hdl.handle.net/11449/21035710.1016/j.clnesp.2021.03.026WOS:000653468300012Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengClinical Nutrition Espeninfo:eu-repo/semantics/openAccess2024-06-18T18:18:06Zoai:repositorio.unesp.br:11449/210357Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-06-18T18:18:06Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial |
title |
Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial |
spellingShingle |
Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial Marini, Ana Clara B. Hemodialysis Phase angle NMES Lean body mass |
title_short |
Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial |
title_full |
Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial |
title_fullStr |
Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial |
title_full_unstemmed |
Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial |
title_sort |
Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial |
author |
Marini, Ana Clara B. |
author_facet |
Marini, Ana Clara B. Motobu, Reika D. Freitas, Ana Tvs Mota, Joao F. Monteiro, Paula A. [UNESP] Pichard, Claude Laviano, Alessandro Wall, Benjamin T. Pimentel, Gustavo D. |
author_role |
author |
author2 |
Motobu, Reika D. Freitas, Ana Tvs Mota, Joao F. Monteiro, Paula A. [UNESP] Pichard, Claude Laviano, Alessandro Wall, Benjamin T. Pimentel, Gustavo D. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de Goiás (UFG) Universidade Estadual Paulista (Unesp) Geneva Univ Hosp Univ Roma La Sapienza Univ Exeter |
dc.contributor.author.fl_str_mv |
Marini, Ana Clara B. Motobu, Reika D. Freitas, Ana Tvs Mota, Joao F. Monteiro, Paula A. [UNESP] Pichard, Claude Laviano, Alessandro Wall, Benjamin T. Pimentel, Gustavo D. |
dc.subject.por.fl_str_mv |
Hemodialysis Phase angle NMES Lean body mass |
topic |
Hemodialysis Phase angle NMES Lean body mass |
description |
Purpose: Neuromuscular electrical stimulation (NMES) elicits muscle contraction and has been shown to attenuate muscle atrophy when physical activity is not possible. Thus, we hypothesized that intradialytic NMES would attenuate the loss leg lean mass and improve the phase angle in patients undergoing hemodialysis (HD). Methods: A randomized controlled trial was performed with twenty-one adult HD patients (n = 8 F, n = 13 M; 45.8 +/- 10.6 y) randomly assigned to usual care (control group, n = 11; 4F/7M) or to the NMES group (n = 10; 4F/6M). NMES was applied bilaterally at the origin and insertion points of the quadriceps or gastrocnemius muscles for 40 min during each HD session (3x/wk for one month). Pre-and post-intervention, we measured leg lean mass using dual-energy x-ray absorptiometry and phase angle using bioelectrical impedance analysis. Results: NMES did not change leg lean mass compared to the control group. Phase angle increased in the NMES compared to the control group (Delta: +0.71 +/- 0.27 degrees vs. -0.46 +/- 0.23 degrees, p = 0.004) with interaction time x treatment (ANOVA p = 0.004). Conclusion: Short-term intradialytic NMES targeting muscles of the legs improved the phase angle but did not change leg lean mass. Brazilian registry of clinical trials under the code: RBR-98wzgn. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T15:05:58Z 2021-06-25T15:05:58Z 2021-06-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.clnesp.2021.03.026 Clinical Nutrition Espen. Amsterdam: Elsevier, v. 43, p. 111-116, 2021. 2405-4577 http://hdl.handle.net/11449/210357 10.1016/j.clnesp.2021.03.026 WOS:000653468300012 |
url |
http://dx.doi.org/10.1016/j.clnesp.2021.03.026 http://hdl.handle.net/11449/210357 |
identifier_str_mv |
Clinical Nutrition Espen. Amsterdam: Elsevier, v. 43, p. 111-116, 2021. 2405-4577 10.1016/j.clnesp.2021.03.026 WOS:000653468300012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Clinical Nutrition Espen |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
111-116 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803649917716004864 |