Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/pathogens9090706 http://hdl.handle.net/11449/202058 |
Resumo: | Among the new diagnostic methods for mastitis detection under development, milk acute-phase proteins (APPs) are receiving special attention. The study aimed to compare the profile of milk APPs from cows with natural clinical mastitis caused by distinct pathogens. The concentrations of haptoglobin (Hp), serum amyloid A (SAA), alpha-1-acid glycoprotein (AGP), and C-reactive protein (CRP) were measured by Spatial Proximity Analyte Reagent Capture Luminescence (SPARCL). Each APP was compared across the pathogens causing mastitis. The APPs differed statistically (p < 0.05) among the pathogens causing udder infection. There were significant and positive correlations among the concentration profile, for each pathogen, in three of four APPs studied. It can be concluded that the pathogen causing mastitis could modify the profile of release of the APPs in milk. The profile of Hp, AGP, and CRP demonstrated significant correlation, indicating that the three APPs are suggested as biomarkers, in milk, for bovine mastitis. |
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Repositório Institucional da UNESP |
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Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogensAcute-phase proteinsCattleDairy ruminantsMastitisSPARCLAmong the new diagnostic methods for mastitis detection under development, milk acute-phase proteins (APPs) are receiving special attention. The study aimed to compare the profile of milk APPs from cows with natural clinical mastitis caused by distinct pathogens. The concentrations of haptoglobin (Hp), serum amyloid A (SAA), alpha-1-acid glycoprotein (AGP), and C-reactive protein (CRP) were measured by Spatial Proximity Analyte Reagent Capture Luminescence (SPARCL). Each APP was compared across the pathogens causing mastitis. The APPs differed statistically (p < 0.05) among the pathogens causing udder infection. There were significant and positive correlations among the concentration profile, for each pathogen, in three of four APPs studied. It can be concluded that the pathogen causing mastitis could modify the profile of release of the APPs in milk. The profile of Hp, AGP, and CRP demonstrated significant correlation, indicating that the three APPs are suggested as biomarkers, in milk, for bovine mastitis.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Animal Production and Preventive Veterinary Medicine Faculty of Medicine Veterinary and Animal Science São Paulo State University (UNESP)Department of Veterinary Clinical Science Faculty of Medicine Veterinary and Animal Science São Paulo State University (UNESP)Applied Animal Biology Faculty of Land and Food Systems University of British ColumbiaLife Diagnosis Inc.Department of Animal Production and Preventive Veterinary Medicine Faculty of Medicine Veterinary and Animal Science São Paulo State University (UNESP)Department of Veterinary Clinical Science Faculty of Medicine Veterinary and Animal Science São Paulo State University (UNESP)FAPESP: 2015/19688-8FAPESP: 2015/26055-1Universidade Estadual Paulista (Unesp)University of British ColumbiaInc.Dalanezi, Felipe M. [UNESP]Schmidt, Elizabeth M. S. [UNESP]Joaquim, Sâmea F. [UNESP]Guimarães, Felipe F. [UNESP]Guerra, Simoni T. [UNESP]Lopes, Bruna C. [UNESP]Cerri, Ronaldo L. A.Chadwick, ChristopherLangoni, Hélio [UNESP]2020-12-12T02:48:43Z2020-12-12T02:48:43Z2020-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-12http://dx.doi.org/10.3390/pathogens9090706Pathogens, v. 9, n. 9, p. 1-12, 2020.2076-0817http://hdl.handle.net/11449/20205810.3390/pathogens90907062-s2.0-85090042902Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPathogensinfo:eu-repo/semantics/openAccess2021-10-23T05:01:54Zoai:repositorio.unesp.br:11449/202058Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T05:01:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens |
title |
Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens |
spellingShingle |
Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens Dalanezi, Felipe M. [UNESP] Acute-phase proteins Cattle Dairy ruminants Mastitis SPARCL |
title_short |
Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens |
title_full |
Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens |
title_fullStr |
Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens |
title_full_unstemmed |
Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens |
title_sort |
Concentrations of acute-phase proteins in milk from cows with clinical mastitis caused by different pathogens |
author |
Dalanezi, Felipe M. [UNESP] |
author_facet |
Dalanezi, Felipe M. [UNESP] Schmidt, Elizabeth M. S. [UNESP] Joaquim, Sâmea F. [UNESP] Guimarães, Felipe F. [UNESP] Guerra, Simoni T. [UNESP] Lopes, Bruna C. [UNESP] Cerri, Ronaldo L. A. Chadwick, Christopher Langoni, Hélio [UNESP] |
author_role |
author |
author2 |
Schmidt, Elizabeth M. S. [UNESP] Joaquim, Sâmea F. [UNESP] Guimarães, Felipe F. [UNESP] Guerra, Simoni T. [UNESP] Lopes, Bruna C. [UNESP] Cerri, Ronaldo L. A. Chadwick, Christopher Langoni, Hélio [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) University of British Columbia Inc. |
dc.contributor.author.fl_str_mv |
Dalanezi, Felipe M. [UNESP] Schmidt, Elizabeth M. S. [UNESP] Joaquim, Sâmea F. [UNESP] Guimarães, Felipe F. [UNESP] Guerra, Simoni T. [UNESP] Lopes, Bruna C. [UNESP] Cerri, Ronaldo L. A. Chadwick, Christopher Langoni, Hélio [UNESP] |
dc.subject.por.fl_str_mv |
Acute-phase proteins Cattle Dairy ruminants Mastitis SPARCL |
topic |
Acute-phase proteins Cattle Dairy ruminants Mastitis SPARCL |
description |
Among the new diagnostic methods for mastitis detection under development, milk acute-phase proteins (APPs) are receiving special attention. The study aimed to compare the profile of milk APPs from cows with natural clinical mastitis caused by distinct pathogens. The concentrations of haptoglobin (Hp), serum amyloid A (SAA), alpha-1-acid glycoprotein (AGP), and C-reactive protein (CRP) were measured by Spatial Proximity Analyte Reagent Capture Luminescence (SPARCL). Each APP was compared across the pathogens causing mastitis. The APPs differed statistically (p < 0.05) among the pathogens causing udder infection. There were significant and positive correlations among the concentration profile, for each pathogen, in three of four APPs studied. It can be concluded that the pathogen causing mastitis could modify the profile of release of the APPs in milk. The profile of Hp, AGP, and CRP demonstrated significant correlation, indicating that the three APPs are suggested as biomarkers, in milk, for bovine mastitis. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T02:48:43Z 2020-12-12T02:48:43Z 2020-09-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/pathogens9090706 Pathogens, v. 9, n. 9, p. 1-12, 2020. 2076-0817 http://hdl.handle.net/11449/202058 10.3390/pathogens9090706 2-s2.0-85090042902 |
url |
http://dx.doi.org/10.3390/pathogens9090706 http://hdl.handle.net/11449/202058 |
identifier_str_mv |
Pathogens, v. 9, n. 9, p. 1-12, 2020. 2076-0817 10.3390/pathogens9090706 2-s2.0-85090042902 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Pathogens |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-12 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803649822179196928 |