Avaliação do desempenho do ozônio e do cloro na remoção do fármaco ácido mefenâmico solúvel em água

• Autor(a) principal: Tuha, Tatiane Arissa [UNESP]
• Data de Publicação: 2017
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/156246; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2018-02-22/000894313.pdf
• topic: Abastecimento de água; Hidrologia; Água - Purificação; Fármacos; Cloro; Ozonio; Oxidação; Água - Poluição; Cromatografia líquida de alta eficiência

The contamination of the environment by pharmaceutical compounds has become a great concern due to the negative impacts they can possibly cause to humans, or to aquatic and terrestrial organisms. Different options of water treatments to remove this variety of pollutant are a matter of interest, given that conventional treatments used in wastewater treatment plants (WTP) are not efficient, and the detection of pharmaceuticals substances have been reported in several aqueous matrices, such as sewage, effluents from WTP, surface and groundwater, and even tap water. For these reasons, this study evaluates the oxidation performance by ozone and chlorine in the removal of soluble mefenamic acid (MEFS) in water. Previously, it was necessary to investigate the use of surfactants (Tween 80, Extran and common detergent) in the concentration of 1% (v/v) to increase the solubility of mefenamic acid in water, being chosen the addition of Extran 1% (v/v) surfactant in samples. Then, oxidation experiments were carried out in bench scale, testing different doses of ozone (8,17 mg/L; 10,21 mg/L; 20,42 mg/L; 29,61 mg/L; 40,03 mg/L; 50,04 mg/L; 60,05 mg/L and 70,00 mg/L) and chlorine (10,21 mg/L; 20,42 mg/L; 29,61 mg/L; 40,03 mg/L; 50,04 mg/L and 60,05 mg/L), with oxidation time of three minutes and neutral pH.. The quantification analysis of the drug were conducted by high performance liquid chromatography (HPLC). The results shows that the removal efficiency is increased along with the increment of the applied dose of oxidant. However, in higher doses (40,03 mg/L; 50,04 mg/L; 60,05 mg/L for both, and 70,00 mg/L for ozone) the efficiency is limited and tends to plateau, near 60% for ozone and close to 46% for chlorine, possibly because of the addition of the surfactant Extran 1% (v/v). In conclusion, both treatments showed removal potential of MEFS and the results shows a higher efficiency by...