COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum

Detalhes bibliográficos
Autor(a) principal: Knobel, Roxana
Data de Publicação: 2021
Outros Autores: Takemoto, Maíra L. S. [UNESP], Nakamura-Pereira, Marcos, Menezes, Mariane O. [UNESP], Borges, Vicente K., Katz, Leila, Amorim, Melania M. R., Andreucci, Carla B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1002/ijgo.13811
http://hdl.handle.net/11449/221982
Resumo: Objective: To compare risk of death due to COVID-19 among pregnant, postpartum, and non-pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS-SS). Methods: A secondary analysis was performed of the Brazilian official SARS-SS, with data retrieved up to August 17, 2020. Cases were stratified by pregnancy status, risk factors or co-morbidities, and outcome (death or recovery). Multiple logistic regression was employed to examine associations between independent variables and risk of death. Results: A total of 24 805 cases were included, with 3129 deaths (12.6%), including 271 maternal deaths. Postpartum was associated with increased risk of death, admission to the intensive care unit (ICU), and mechanical ventilation. Co-morbidities with higher impact on case fatality rate among non-obstetric cases were cancer and neurological and kidney diseases. Among pregnant women, cancer, diabetes mellitus, obesity, and rheumatology diseases were associated with risk of death. In the postpartum subgroup, age over 35 years and diabetes mellitus were independently associated with higher chance of death. Conclusion: Postpartum was associated with worse outcomes among the obstetric population, despite lower risk of dying without accessing ICU care. Non-pregnant women with cancer, neurological diseases, and kidney diseases have a higher risk of death due to COVID-19.
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spelling COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartumcardiovascular diseaseCOVID-19maternal deathobesitypostpartumpregnancywomen of reproductive ageObjective: To compare risk of death due to COVID-19 among pregnant, postpartum, and non-pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS-SS). Methods: A secondary analysis was performed of the Brazilian official SARS-SS, with data retrieved up to August 17, 2020. Cases were stratified by pregnancy status, risk factors or co-morbidities, and outcome (death or recovery). Multiple logistic regression was employed to examine associations between independent variables and risk of death. Results: A total of 24 805 cases were included, with 3129 deaths (12.6%), including 271 maternal deaths. Postpartum was associated with increased risk of death, admission to the intensive care unit (ICU), and mechanical ventilation. Co-morbidities with higher impact on case fatality rate among non-obstetric cases were cancer and neurological and kidney diseases. Among pregnant women, cancer, diabetes mellitus, obesity, and rheumatology diseases were associated with risk of death. In the postpartum subgroup, age over 35 years and diabetes mellitus were independently associated with higher chance of death. Conclusion: Postpartum was associated with worse outcomes among the obstetric population, despite lower risk of dying without accessing ICU care. Non-pregnant women with cancer, neurological diseases, and kidney diseases have a higher risk of death due to COVID-19.Department of Gynecology and Obstetrics Federal University of Santa Catarina (UFSCSão Paulo State University (UNESP Medical School of BotucatuNational Institute for Women Children and Adolescents Health Fernandes Figueira Oswaldo Cruz FoundationDepartment of Automation and Systems Control and Automation Engineering Program Federal University of Santa Catarina (UFSCFernando Figueira Institute of Integral Medicine (IMIPDepartment of Medicine Federal University of Sao Carlos (UFSCARSão Paulo State University (UNESP Medical School of BotucatuUniversidade Federal de Santa Catarina (UFSC)Universidade Estadual Paulista (UNESP)Oswaldo Cruz FoundationFernando Figueira Institute of Integral Medicine (IMIPUniversidade Federal de São Carlos (UFSCar)Knobel, RoxanaTakemoto, Maíra L. S. [UNESP]Nakamura-Pereira, MarcosMenezes, Mariane O. [UNESP]Borges, Vicente K.Katz, LeilaAmorim, Melania M. R.Andreucci, Carla B.2022-04-28T19:41:39Z2022-04-28T19:41:39Z2021-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article101-109http://dx.doi.org/10.1002/ijgo.13811International Journal of Gynecology and Obstetrics, v. 155, n. 1, p. 101-109, 2021.1879-34790020-7292http://hdl.handle.net/11449/22198210.1002/ijgo.138112-s2.0-85110521003Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Gynecology and Obstetricsinfo:eu-repo/semantics/openAccess2022-04-28T19:41:39Zoai:repositorio.unesp.br:11449/221982Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:35:03.637187Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
title COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
spellingShingle COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
Knobel, Roxana
cardiovascular disease
COVID-19
maternal death
obesity
postpartum
pregnancy
women of reproductive age
title_short COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
title_full COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
title_fullStr COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
title_full_unstemmed COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
title_sort COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
author Knobel, Roxana
author_facet Knobel, Roxana
Takemoto, Maíra L. S. [UNESP]
Nakamura-Pereira, Marcos
Menezes, Mariane O. [UNESP]
Borges, Vicente K.
Katz, Leila
Amorim, Melania M. R.
Andreucci, Carla B.
author_role author
author2 Takemoto, Maíra L. S. [UNESP]
Nakamura-Pereira, Marcos
Menezes, Mariane O. [UNESP]
Borges, Vicente K.
Katz, Leila
Amorim, Melania M. R.
Andreucci, Carla B.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de Santa Catarina (UFSC)
Universidade Estadual Paulista (UNESP)
Oswaldo Cruz Foundation
Fernando Figueira Institute of Integral Medicine (IMIP
Universidade Federal de São Carlos (UFSCar)
dc.contributor.author.fl_str_mv Knobel, Roxana
Takemoto, Maíra L. S. [UNESP]
Nakamura-Pereira, Marcos
Menezes, Mariane O. [UNESP]
Borges, Vicente K.
Katz, Leila
Amorim, Melania M. R.
Andreucci, Carla B.
dc.subject.por.fl_str_mv cardiovascular disease
COVID-19
maternal death
obesity
postpartum
pregnancy
women of reproductive age
topic cardiovascular disease
COVID-19
maternal death
obesity
postpartum
pregnancy
women of reproductive age
description Objective: To compare risk of death due to COVID-19 among pregnant, postpartum, and non-pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS-SS). Methods: A secondary analysis was performed of the Brazilian official SARS-SS, with data retrieved up to August 17, 2020. Cases were stratified by pregnancy status, risk factors or co-morbidities, and outcome (death or recovery). Multiple logistic regression was employed to examine associations between independent variables and risk of death. Results: A total of 24 805 cases were included, with 3129 deaths (12.6%), including 271 maternal deaths. Postpartum was associated with increased risk of death, admission to the intensive care unit (ICU), and mechanical ventilation. Co-morbidities with higher impact on case fatality rate among non-obstetric cases were cancer and neurological and kidney diseases. Among pregnant women, cancer, diabetes mellitus, obesity, and rheumatology diseases were associated with risk of death. In the postpartum subgroup, age over 35 years and diabetes mellitus were independently associated with higher chance of death. Conclusion: Postpartum was associated with worse outcomes among the obstetric population, despite lower risk of dying without accessing ICU care. Non-pregnant women with cancer, neurological diseases, and kidney diseases have a higher risk of death due to COVID-19.
publishDate 2021
dc.date.none.fl_str_mv 2021-10-01
2022-04-28T19:41:39Z
2022-04-28T19:41:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1002/ijgo.13811
International Journal of Gynecology and Obstetrics, v. 155, n. 1, p. 101-109, 2021.
1879-3479
0020-7292
http://hdl.handle.net/11449/221982
10.1002/ijgo.13811
2-s2.0-85110521003
url http://dx.doi.org/10.1002/ijgo.13811
http://hdl.handle.net/11449/221982
identifier_str_mv International Journal of Gynecology and Obstetrics, v. 155, n. 1, p. 101-109, 2021.
1879-3479
0020-7292
10.1002/ijgo.13811
2-s2.0-85110521003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Journal of Gynecology and Obstetrics
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 101-109
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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