COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1002/ijgo.13811 http://hdl.handle.net/11449/221982 |
Resumo: | Objective: To compare risk of death due to COVID-19 among pregnant, postpartum, and non-pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS-SS). Methods: A secondary analysis was performed of the Brazilian official SARS-SS, with data retrieved up to August 17, 2020. Cases were stratified by pregnancy status, risk factors or co-morbidities, and outcome (death or recovery). Multiple logistic regression was employed to examine associations between independent variables and risk of death. Results: A total of 24 805 cases were included, with 3129 deaths (12.6%), including 271 maternal deaths. Postpartum was associated with increased risk of death, admission to the intensive care unit (ICU), and mechanical ventilation. Co-morbidities with higher impact on case fatality rate among non-obstetric cases were cancer and neurological and kidney diseases. Among pregnant women, cancer, diabetes mellitus, obesity, and rheumatology diseases were associated with risk of death. In the postpartum subgroup, age over 35 years and diabetes mellitus were independently associated with higher chance of death. Conclusion: Postpartum was associated with worse outcomes among the obstetric population, despite lower risk of dying without accessing ICU care. Non-pregnant women with cancer, neurological diseases, and kidney diseases have a higher risk of death due to COVID-19. |
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Repositório Institucional da UNESP |
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COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartumcardiovascular diseaseCOVID-19maternal deathobesitypostpartumpregnancywomen of reproductive ageObjective: To compare risk of death due to COVID-19 among pregnant, postpartum, and non-pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS-SS). Methods: A secondary analysis was performed of the Brazilian official SARS-SS, with data retrieved up to August 17, 2020. Cases were stratified by pregnancy status, risk factors or co-morbidities, and outcome (death or recovery). Multiple logistic regression was employed to examine associations between independent variables and risk of death. Results: A total of 24 805 cases were included, with 3129 deaths (12.6%), including 271 maternal deaths. Postpartum was associated with increased risk of death, admission to the intensive care unit (ICU), and mechanical ventilation. Co-morbidities with higher impact on case fatality rate among non-obstetric cases were cancer and neurological and kidney diseases. Among pregnant women, cancer, diabetes mellitus, obesity, and rheumatology diseases were associated with risk of death. In the postpartum subgroup, age over 35 years and diabetes mellitus were independently associated with higher chance of death. Conclusion: Postpartum was associated with worse outcomes among the obstetric population, despite lower risk of dying without accessing ICU care. Non-pregnant women with cancer, neurological diseases, and kidney diseases have a higher risk of death due to COVID-19.Department of Gynecology and Obstetrics Federal University of Santa Catarina (UFSCSão Paulo State University (UNESP Medical School of BotucatuNational Institute for Women Children and Adolescents Health Fernandes Figueira Oswaldo Cruz FoundationDepartment of Automation and Systems Control and Automation Engineering Program Federal University of Santa Catarina (UFSCFernando Figueira Institute of Integral Medicine (IMIPDepartment of Medicine Federal University of Sao Carlos (UFSCARSão Paulo State University (UNESP Medical School of BotucatuUniversidade Federal de Santa Catarina (UFSC)Universidade Estadual Paulista (UNESP)Oswaldo Cruz FoundationFernando Figueira Institute of Integral Medicine (IMIPUniversidade Federal de São Carlos (UFSCar)Knobel, RoxanaTakemoto, Maíra L. S. [UNESP]Nakamura-Pereira, MarcosMenezes, Mariane O. [UNESP]Borges, Vicente K.Katz, LeilaAmorim, Melania M. R.Andreucci, Carla B.2022-04-28T19:41:39Z2022-04-28T19:41:39Z2021-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article101-109http://dx.doi.org/10.1002/ijgo.13811International Journal of Gynecology and Obstetrics, v. 155, n. 1, p. 101-109, 2021.1879-34790020-7292http://hdl.handle.net/11449/22198210.1002/ijgo.138112-s2.0-85110521003Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Gynecology and Obstetricsinfo:eu-repo/semantics/openAccess2022-04-28T19:41:39Zoai:repositorio.unesp.br:11449/221982Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:35:03.637187Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum |
title |
COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum |
spellingShingle |
COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum Knobel, Roxana cardiovascular disease COVID-19 maternal death obesity postpartum pregnancy women of reproductive age |
title_short |
COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum |
title_full |
COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum |
title_fullStr |
COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum |
title_full_unstemmed |
COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum |
title_sort |
COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum |
author |
Knobel, Roxana |
author_facet |
Knobel, Roxana Takemoto, Maíra L. S. [UNESP] Nakamura-Pereira, Marcos Menezes, Mariane O. [UNESP] Borges, Vicente K. Katz, Leila Amorim, Melania M. R. Andreucci, Carla B. |
author_role |
author |
author2 |
Takemoto, Maíra L. S. [UNESP] Nakamura-Pereira, Marcos Menezes, Mariane O. [UNESP] Borges, Vicente K. Katz, Leila Amorim, Melania M. R. Andreucci, Carla B. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de Santa Catarina (UFSC) Universidade Estadual Paulista (UNESP) Oswaldo Cruz Foundation Fernando Figueira Institute of Integral Medicine (IMIP Universidade Federal de São Carlos (UFSCar) |
dc.contributor.author.fl_str_mv |
Knobel, Roxana Takemoto, Maíra L. S. [UNESP] Nakamura-Pereira, Marcos Menezes, Mariane O. [UNESP] Borges, Vicente K. Katz, Leila Amorim, Melania M. R. Andreucci, Carla B. |
dc.subject.por.fl_str_mv |
cardiovascular disease COVID-19 maternal death obesity postpartum pregnancy women of reproductive age |
topic |
cardiovascular disease COVID-19 maternal death obesity postpartum pregnancy women of reproductive age |
description |
Objective: To compare risk of death due to COVID-19 among pregnant, postpartum, and non-pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS-SS). Methods: A secondary analysis was performed of the Brazilian official SARS-SS, with data retrieved up to August 17, 2020. Cases were stratified by pregnancy status, risk factors or co-morbidities, and outcome (death or recovery). Multiple logistic regression was employed to examine associations between independent variables and risk of death. Results: A total of 24 805 cases were included, with 3129 deaths (12.6%), including 271 maternal deaths. Postpartum was associated with increased risk of death, admission to the intensive care unit (ICU), and mechanical ventilation. Co-morbidities with higher impact on case fatality rate among non-obstetric cases were cancer and neurological and kidney diseases. Among pregnant women, cancer, diabetes mellitus, obesity, and rheumatology diseases were associated with risk of death. In the postpartum subgroup, age over 35 years and diabetes mellitus were independently associated with higher chance of death. Conclusion: Postpartum was associated with worse outcomes among the obstetric population, despite lower risk of dying without accessing ICU care. Non-pregnant women with cancer, neurological diseases, and kidney diseases have a higher risk of death due to COVID-19. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-01 2022-04-28T19:41:39Z 2022-04-28T19:41:39Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1002/ijgo.13811 International Journal of Gynecology and Obstetrics, v. 155, n. 1, p. 101-109, 2021. 1879-3479 0020-7292 http://hdl.handle.net/11449/221982 10.1002/ijgo.13811 2-s2.0-85110521003 |
url |
http://dx.doi.org/10.1002/ijgo.13811 http://hdl.handle.net/11449/221982 |
identifier_str_mv |
International Journal of Gynecology and Obstetrics, v. 155, n. 1, p. 101-109, 2021. 1879-3479 0020-7292 10.1002/ijgo.13811 2-s2.0-85110521003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Journal of Gynecology and Obstetrics |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
101-109 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128674966274048 |