Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/1678-9199-20-3 http://hdl.handle.net/11449/113333 |
Resumo: | Background: Scorpion envenomations are a major public health problem in Brazil, whose most dangerous cases are attributable to the genus Tityus. This study was designed to compare the clinical and demographic features of envenomations by Tityus obscurus in two areas of the state of Para located in the Amazon basin. Were compared demographic findings, local and systemic signs and symptoms of human envenomations caused by T. obscurus that occurred in western and eastern areas of the state.Results: Forty-eight patients with confirmed envenomation by T. obscurus were evaluated from January 2008 to July 2011. Most of them came from the eastern region, where male and female patients were present in similar numbers, while males predominated in the west. Median age groups were also similar in both areas. Most scorpion stings took place during the day and occurred significantly more frequently on the upper limbs. The time between the sting and admission to the health center was less than three hours in both areas. Most eastern patients had local manifestations while in the west, systemic manifestations predominated. Local symptoms were similar in both areas, but systemic signs and symptoms were more common in the west. Symptoms frequently observed at the sting site were local and radiating pain, paresthesia, edema, erythema, sweating, piloerection and burning. The systemic manifestations were significantly higher in patients from the west. Futhermore, neurological symptoms such as general paresthesia, ataxia, dysarthria, myoclonus, dysmetria, and electric shock-like sensations throughout the body were reported only by patients from the west.Conclusion: The present study shows that two regions of Para state differ in the clinical manifestations and severity of confirmed envenomation by T. obscurus which suggests a toxicity variation resulting from the diversity of T. obscurus venom in different areas of the Brazilian Amazon basin, and that T. serrulatus antivenom can be successfully used against T. obscurus. |
id |
UNSP_c5bdb361851dcba9765879c0f20cf06c |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/113333 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case seriesScorpionismTityus obscurusEnvenomingNeurological symptomsBrazilian AmazonBackground: Scorpion envenomations are a major public health problem in Brazil, whose most dangerous cases are attributable to the genus Tityus. This study was designed to compare the clinical and demographic features of envenomations by Tityus obscurus in two areas of the state of Para located in the Amazon basin. Were compared demographic findings, local and systemic signs and symptoms of human envenomations caused by T. obscurus that occurred in western and eastern areas of the state.Results: Forty-eight patients with confirmed envenomation by T. obscurus were evaluated from January 2008 to July 2011. Most of them came from the eastern region, where male and female patients were present in similar numbers, while males predominated in the west. Median age groups were also similar in both areas. Most scorpion stings took place during the day and occurred significantly more frequently on the upper limbs. The time between the sting and admission to the health center was less than three hours in both areas. Most eastern patients had local manifestations while in the west, systemic manifestations predominated. Local symptoms were similar in both areas, but systemic signs and symptoms were more common in the west. Symptoms frequently observed at the sting site were local and radiating pain, paresthesia, edema, erythema, sweating, piloerection and burning. The systemic manifestations were significantly higher in patients from the west. Futhermore, neurological symptoms such as general paresthesia, ataxia, dysarthria, myoclonus, dysmetria, and electric shock-like sensations throughout the body were reported only by patients from the west.Conclusion: The present study shows that two regions of Para state differ in the clinical manifestations and severity of confirmed envenomation by T. obscurus which suggests a toxicity variation resulting from the diversity of T. obscurus venom in different areas of the Brazilian Amazon basin, and that T. serrulatus antivenom can be successfully used against T. obscurus.Para Federal University Foundation for Research (FADESP)Fed Univ Para, Ctr Trop Med, Lab Med Entomol & Venomous Anim, BR-66055240 Belem, Para, BrazilSao Paulo State Univ, Dept Biol Sci, UNESP, Univ Estadual Paulista, BR-19806390 Assis, SP, BrazilHosp Municipal Santarem, BR-68005110 Santarem, Para, BrazilFac Integrada Tapajos, BR-68010200 Santarem, Para, BrazilSao Paulo State Univ, Dept Biol Sci, UNESP, Univ Estadual Paulista, BR-19806390 Assis, SP, BrazilBiomed Central Ltd.Fed Univ ParaUniversidade Estadual Paulista (Unesp)Hosp Municipal SantaremFac Integrada TapajosPardal, Pedro P. O.Ishikawa, Edna A. Y.Vieira, Jose L. F.Coelho, Johne S.Dorea, Regina C. C. [UNESP]Abati, Paulo A. M.Quiroga, Mariana M. M.Chalkidis, Hipocrates M.2014-12-03T13:11:37Z2014-12-03T13:11:37Z2014-02-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://dx.doi.org/10.1186/1678-9199-20-3Journal Of Venomous Animals And Toxins Including Tropical Diseases. London: Biomed Central Ltd, v. 20, 7 p., 2014.1678-9199http://hdl.handle.net/11449/11333310.1186/1678-9199-20-3WOS:000334696500001WOS000334696500001.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2024-06-13T17:38:19Zoai:repositorio.unesp.br:11449/113333Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:22:39.650917Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series |
title |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series |
spellingShingle |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series Pardal, Pedro P. O. Scorpionism Tityus obscurus Envenoming Neurological symptoms Brazilian Amazon |
title_short |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series |
title_full |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series |
title_fullStr |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series |
title_full_unstemmed |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series |
title_sort |
Clinical aspects of envenomation caused by Tityus obscurus (Gervais, 1843) in two distinct regions of Para state, Brazilian Amazon basin: a prospective case series |
author |
Pardal, Pedro P. O. |
author_facet |
Pardal, Pedro P. O. Ishikawa, Edna A. Y. Vieira, Jose L. F. Coelho, Johne S. Dorea, Regina C. C. [UNESP] Abati, Paulo A. M. Quiroga, Mariana M. M. Chalkidis, Hipocrates M. |
author_role |
author |
author2 |
Ishikawa, Edna A. Y. Vieira, Jose L. F. Coelho, Johne S. Dorea, Regina C. C. [UNESP] Abati, Paulo A. M. Quiroga, Mariana M. M. Chalkidis, Hipocrates M. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Fed Univ Para Universidade Estadual Paulista (Unesp) Hosp Municipal Santarem Fac Integrada Tapajos |
dc.contributor.author.fl_str_mv |
Pardal, Pedro P. O. Ishikawa, Edna A. Y. Vieira, Jose L. F. Coelho, Johne S. Dorea, Regina C. C. [UNESP] Abati, Paulo A. M. Quiroga, Mariana M. M. Chalkidis, Hipocrates M. |
dc.subject.por.fl_str_mv |
Scorpionism Tityus obscurus Envenoming Neurological symptoms Brazilian Amazon |
topic |
Scorpionism Tityus obscurus Envenoming Neurological symptoms Brazilian Amazon |
description |
Background: Scorpion envenomations are a major public health problem in Brazil, whose most dangerous cases are attributable to the genus Tityus. This study was designed to compare the clinical and demographic features of envenomations by Tityus obscurus in two areas of the state of Para located in the Amazon basin. Were compared demographic findings, local and systemic signs and symptoms of human envenomations caused by T. obscurus that occurred in western and eastern areas of the state.Results: Forty-eight patients with confirmed envenomation by T. obscurus were evaluated from January 2008 to July 2011. Most of them came from the eastern region, where male and female patients were present in similar numbers, while males predominated in the west. Median age groups were also similar in both areas. Most scorpion stings took place during the day and occurred significantly more frequently on the upper limbs. The time between the sting and admission to the health center was less than three hours in both areas. Most eastern patients had local manifestations while in the west, systemic manifestations predominated. Local symptoms were similar in both areas, but systemic signs and symptoms were more common in the west. Symptoms frequently observed at the sting site were local and radiating pain, paresthesia, edema, erythema, sweating, piloerection and burning. The systemic manifestations were significantly higher in patients from the west. Futhermore, neurological symptoms such as general paresthesia, ataxia, dysarthria, myoclonus, dysmetria, and electric shock-like sensations throughout the body were reported only by patients from the west.Conclusion: The present study shows that two regions of Para state differ in the clinical manifestations and severity of confirmed envenomation by T. obscurus which suggests a toxicity variation resulting from the diversity of T. obscurus venom in different areas of the Brazilian Amazon basin, and that T. serrulatus antivenom can be successfully used against T. obscurus. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-03T13:11:37Z 2014-12-03T13:11:37Z 2014-02-11 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/1678-9199-20-3 Journal Of Venomous Animals And Toxins Including Tropical Diseases. London: Biomed Central Ltd, v. 20, 7 p., 2014. 1678-9199 http://hdl.handle.net/11449/113333 10.1186/1678-9199-20-3 WOS:000334696500001 WOS000334696500001.pdf |
url |
http://dx.doi.org/10.1186/1678-9199-20-3 http://hdl.handle.net/11449/113333 |
identifier_str_mv |
Journal Of Venomous Animals And Toxins Including Tropical Diseases. London: Biomed Central Ltd, v. 20, 7 p., 2014. 1678-9199 10.1186/1678-9199-20-3 WOS:000334696500001 WOS000334696500001.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases 1.782 0,573 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
7 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd. |
publisher.none.fl_str_mv |
Biomed Central Ltd. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128801040760832 |