Síndrome antifosfolípide e trombocitopenia na infância
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0103-05822012000300021 http://hdl.handle.net/11449/73536 |
Resumo: | Objective: To report the case of a child diagnosed with antiphospholipid syndrome associated with severe thrombocytopenia, and to review the literature on the subject. Case description: Child aged nine years and eight months old with severe thrombocytopenia associated with a positive anticardiolipin antibody. Data were collected by clinical history, physical examination, and laboratorial exams. Diagnosis was confirmed according to criteria established for the antiophospholipid syndrome, associated with the presence of the most common manifestations of the syndrome in children: livedo reticularis and thrombocytopenia. Comments: The antiphospholipid syndrome is an uncommon pediatric disease, and clinical manifestations such as decreased platelet number should be considered. |
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Síndrome antifosfolípide e trombocitopenia na infânciaAntiphospholipid syndrome and thrombocytopenia in childhoodAntiphospholipid syndromeLivedo reticularisThrombocytopeniabeta2 glycoprotein 1 antibodycardiolipin antibodyhemoglobinhydroxychloroquineimmunoglobulin G antibodyimmunoglobulin M antibodylupus anticoagulantprednisoneantiphospholipid syndromecase reportchilddisease associationdisease severitydrug dose reductionecchymosisepistaxisfemalegingiva bleedinghemoglobin blood levelhumanidiopathic thrombocytopenic purpuralivedo reticularismedical historyphysical examinationschool childthrombocyte countthrombocytopeniaObjective: To report the case of a child diagnosed with antiphospholipid syndrome associated with severe thrombocytopenia, and to review the literature on the subject. Case description: Child aged nine years and eight months old with severe thrombocytopenia associated with a positive anticardiolipin antibody. Data were collected by clinical history, physical examination, and laboratorial exams. Diagnosis was confirmed according to criteria established for the antiophospholipid syndrome, associated with the presence of the most common manifestations of the syndrome in children: livedo reticularis and thrombocytopenia. Comments: The antiphospholipid syndrome is an uncommon pediatric disease, and clinical manifestations such as decreased platelet number should be considered.Instituição: Hospital Pequeno Príncipe, CuritibaUniversidade Católica do Paraná (PUC-PR), Curitiba, PRUniversidade de São Paulo (USP)Universidade Estadual Júlio de Mesquita Filho (Unesp)Universidade Estadual Júlio de Mesquita Filho (Unesp)Instituição: Hospital Pequeno PríncipePontifícia Universidade Católica do Paraná (PUCPR)Universidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Turini, Roberta Bittencourt F.Chechia, Taiana EmílioFernandes, Tadeu AugustoBom, Ana Paula K. P.Bandeira, Márcia [UNESP]2014-05-27T11:26:57Z2014-05-27T11:26:57Z2012-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article443-449application/pdfhttp://dx.doi.org/10.1590/S0103-05822012000300021Revista Paulista de Pediatria, v. 30, n. 3, p. 443-449, 2012.0103-0582http://hdl.handle.net/11449/7353610.1590/S0103-05822012000300021S0103-058220120003000212-s2.0-848680237242-s2.0-84868023724.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporRevista Paulista de Pediatria0,472info:eu-repo/semantics/openAccess2023-12-22T06:26:03Zoai:repositorio.unesp.br:11449/73536Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:02:57.427539Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Síndrome antifosfolípide e trombocitopenia na infância Antiphospholipid syndrome and thrombocytopenia in childhood |
title |
Síndrome antifosfolípide e trombocitopenia na infância |
spellingShingle |
Síndrome antifosfolípide e trombocitopenia na infância Turini, Roberta Bittencourt F. Antiphospholipid syndrome Livedo reticularis Thrombocytopenia beta2 glycoprotein 1 antibody cardiolipin antibody hemoglobin hydroxychloroquine immunoglobulin G antibody immunoglobulin M antibody lupus anticoagulant prednisone antiphospholipid syndrome case report child disease association disease severity drug dose reduction ecchymosis epistaxis female gingiva bleeding hemoglobin blood level human idiopathic thrombocytopenic purpura livedo reticularis medical history physical examination school child thrombocyte count thrombocytopenia |
title_short |
Síndrome antifosfolípide e trombocitopenia na infância |
title_full |
Síndrome antifosfolípide e trombocitopenia na infância |
title_fullStr |
Síndrome antifosfolípide e trombocitopenia na infância |
title_full_unstemmed |
Síndrome antifosfolípide e trombocitopenia na infância |
title_sort |
Síndrome antifosfolípide e trombocitopenia na infância |
author |
Turini, Roberta Bittencourt F. |
author_facet |
Turini, Roberta Bittencourt F. Chechia, Taiana Emílio Fernandes, Tadeu Augusto Bom, Ana Paula K. P. Bandeira, Márcia [UNESP] |
author_role |
author |
author2 |
Chechia, Taiana Emílio Fernandes, Tadeu Augusto Bom, Ana Paula K. P. Bandeira, Márcia [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Instituição: Hospital Pequeno Príncipe Pontifícia Universidade Católica do Paraná (PUCPR) Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Turini, Roberta Bittencourt F. Chechia, Taiana Emílio Fernandes, Tadeu Augusto Bom, Ana Paula K. P. Bandeira, Márcia [UNESP] |
dc.subject.por.fl_str_mv |
Antiphospholipid syndrome Livedo reticularis Thrombocytopenia beta2 glycoprotein 1 antibody cardiolipin antibody hemoglobin hydroxychloroquine immunoglobulin G antibody immunoglobulin M antibody lupus anticoagulant prednisone antiphospholipid syndrome case report child disease association disease severity drug dose reduction ecchymosis epistaxis female gingiva bleeding hemoglobin blood level human idiopathic thrombocytopenic purpura livedo reticularis medical history physical examination school child thrombocyte count thrombocytopenia |
topic |
Antiphospholipid syndrome Livedo reticularis Thrombocytopenia beta2 glycoprotein 1 antibody cardiolipin antibody hemoglobin hydroxychloroquine immunoglobulin G antibody immunoglobulin M antibody lupus anticoagulant prednisone antiphospholipid syndrome case report child disease association disease severity drug dose reduction ecchymosis epistaxis female gingiva bleeding hemoglobin blood level human idiopathic thrombocytopenic purpura livedo reticularis medical history physical examination school child thrombocyte count thrombocytopenia |
description |
Objective: To report the case of a child diagnosed with antiphospholipid syndrome associated with severe thrombocytopenia, and to review the literature on the subject. Case description: Child aged nine years and eight months old with severe thrombocytopenia associated with a positive anticardiolipin antibody. Data were collected by clinical history, physical examination, and laboratorial exams. Diagnosis was confirmed according to criteria established for the antiophospholipid syndrome, associated with the presence of the most common manifestations of the syndrome in children: livedo reticularis and thrombocytopenia. Comments: The antiphospholipid syndrome is an uncommon pediatric disease, and clinical manifestations such as decreased platelet number should be considered. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-09-01 2014-05-27T11:26:57Z 2014-05-27T11:26:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0103-05822012000300021 Revista Paulista de Pediatria, v. 30, n. 3, p. 443-449, 2012. 0103-0582 http://hdl.handle.net/11449/73536 10.1590/S0103-05822012000300021 S0103-05822012000300021 2-s2.0-84868023724 2-s2.0-84868023724.pdf |
url |
http://dx.doi.org/10.1590/S0103-05822012000300021 http://hdl.handle.net/11449/73536 |
identifier_str_mv |
Revista Paulista de Pediatria, v. 30, n. 3, p. 443-449, 2012. 0103-0582 10.1590/S0103-05822012000300021 S0103-05822012000300021 2-s2.0-84868023724 2-s2.0-84868023724.pdf |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
Revista Paulista de Pediatria 0,472 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
443-449 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129277588144128 |