Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?

Detalhes bibliográficos
Autor(a) principal: Resende, Ludimila Oliveira [UNESP]
Data de Publicação: 2019
Outros Autores: Scotton Jorge, Marilia Formentini [UNESP], Schmitt, Juliano Vilaverde [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.abd.2018.12.001
http://hdl.handle.net/11449/196537
Resumo: Hyperzincemia and hypercalprotectinemia is a rare inflammatory disease caused by a mutation in the PSTPIP1 gene, with a dysregulation of calprotectin metabolism. Calprotectin is a zinc-binding protein with antimicrobial properties and pro-inflammatory action. The authors report the case of a 20 year-old girl with cutaneous ulcers comparable with pyoderma gangrenosum, growth failure and chronic anemia, who was given the diagnosis of hyperzincemia and hypercalprotectinemia. Measurement of serum zinc and calprotectin concentrations are indicated in these cases. (C) 2019 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.
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spelling Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?ArthritisInflammationSkin manifestationsZincHyperzincemia and hypercalprotectinemia is a rare inflammatory disease caused by a mutation in the PSTPIP1 gene, with a dysregulation of calprotectin metabolism. Calprotectin is a zinc-binding protein with antimicrobial properties and pro-inflammatory action. The authors report the case of a 20 year-old girl with cutaneous ulcers comparable with pyoderma gangrenosum, growth failure and chronic anemia, who was given the diagnosis of hyperzincemia and hypercalprotectinemia. Measurement of serum zinc and calprotectin concentrations are indicated in these cases. (C) 2019 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.Univ Estadual Paulista, Fac Med Botucatu, Botucatu, SP, BrazilUniv Estadual Paulista, Fac Med Botucatu, Dept Dermatol, Botucatu, SP, BrazilUniv Estadual Paulista, Fac Med Botucatu, Hosp Clin, Botucatu, SP, BrazilUniv Estadual Paulista, Fac Med Botucatu, Botucatu, SP, BrazilUniv Estadual Paulista, Fac Med Botucatu, Dept Dermatol, Botucatu, SP, BrazilUniv Estadual Paulista, Fac Med Botucatu, Hosp Clin, Botucatu, SP, BrazilSoc Brasileira DermatologiaUniversidade Estadual Paulista (Unesp)Resende, Ludimila Oliveira [UNESP]Scotton Jorge, Marilia Formentini [UNESP]Schmitt, Juliano Vilaverde [UNESP]2020-12-10T19:48:11Z2020-12-10T19:48:11Z2019-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article713-716application/pdfhttp://dx.doi.org/10.1016/j.abd.2018.12.001Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 6, p. 713-716, 2019.0365-0596http://hdl.handle.net/11449/19653710.1016/j.abd.2018.12.001S0365-05962019000600713WOS:000509999500011S0365-05962019000600713.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAnais Brasileiros De Dermatologiainfo:eu-repo/semantics/openAccess2024-08-14T18:45:33Zoai:repositorio.unesp.br:11449/196537Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T18:45:33Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
title Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
spellingShingle Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
Resende, Ludimila Oliveira [UNESP]
Arthritis
Inflammation
Skin manifestations
Zinc
title_short Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
title_full Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
title_fullStr Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
title_full_unstemmed Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
title_sort Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
author Resende, Ludimila Oliveira [UNESP]
author_facet Resende, Ludimila Oliveira [UNESP]
Scotton Jorge, Marilia Formentini [UNESP]
Schmitt, Juliano Vilaverde [UNESP]
author_role author
author2 Scotton Jorge, Marilia Formentini [UNESP]
Schmitt, Juliano Vilaverde [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Resende, Ludimila Oliveira [UNESP]
Scotton Jorge, Marilia Formentini [UNESP]
Schmitt, Juliano Vilaverde [UNESP]
dc.subject.por.fl_str_mv Arthritis
Inflammation
Skin manifestations
Zinc
topic Arthritis
Inflammation
Skin manifestations
Zinc
description Hyperzincemia and hypercalprotectinemia is a rare inflammatory disease caused by a mutation in the PSTPIP1 gene, with a dysregulation of calprotectin metabolism. Calprotectin is a zinc-binding protein with antimicrobial properties and pro-inflammatory action. The authors report the case of a 20 year-old girl with cutaneous ulcers comparable with pyoderma gangrenosum, growth failure and chronic anemia, who was given the diagnosis of hyperzincemia and hypercalprotectinemia. Measurement of serum zinc and calprotectin concentrations are indicated in these cases. (C) 2019 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.
publishDate 2019
dc.date.none.fl_str_mv 2019-11-01
2020-12-10T19:48:11Z
2020-12-10T19:48:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.abd.2018.12.001
Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 6, p. 713-716, 2019.
0365-0596
http://hdl.handle.net/11449/196537
10.1016/j.abd.2018.12.001
S0365-05962019000600713
WOS:000509999500011
S0365-05962019000600713.pdf
url http://dx.doi.org/10.1016/j.abd.2018.12.001
http://hdl.handle.net/11449/196537
identifier_str_mv Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 6, p. 713-716, 2019.
0365-0596
10.1016/j.abd.2018.12.001
S0365-05962019000600713
WOS:000509999500011
S0365-05962019000600713.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Anais Brasileiros De Dermatologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 713-716
application/pdf
dc.publisher.none.fl_str_mv Soc Brasileira Dermatologia
publisher.none.fl_str_mv Soc Brasileira Dermatologia
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128120288444416

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