Enterococcus spp. em espécimes clínicos de pacientes atendidos em unidades de terapia intensiva

• Autor(a) principal: Gaetti-Jardim Júnior, Elerson [UNESP]
• Data de Publicação: 2014
• Outros Autores: Meca, Lívia Buzati [UNESP], Moreira, Luiza Tavares [UNESP], Bombarda, Fábio, Schweitzer, Christiane Marie [UNESP], Okamoto, Ana Cláudia [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://www.archhealthinvestigation.com.br/index.php/ArcHI/article/view/688; http://hdl.handle.net/11449/133582
• topic: Cross infection; Enterococcus; Periodontitis; Biofilms; Polymerase chain reaction; Infección hospitalaria; Periodontitis; Biofilmes; Reacción en cadena de la polimerasa; Infecção hospitalar; Enterococcus; Periodontite; Biofilmes; Reação em cadeia da polimerase

The relationship between the occurrence of enterococci in the oral microbiota and serious infections in patients hospitalized in intensive care units (ICU) has been established. This study evaluated the presence of Enterococcus faecalis and other species of this genus in the mouths of patients on ICU, correlating it with oral and systemic conditions. Data on health and socioeconomic, medication use, medical and family history of patients maintained for 72 hours in the ICU, diagnosed with severe infection or who have developed this condition after the entry to the unit were obtained. Fifty patients provided intraoral and extraoral clinical samples for analysis (above and subgingival biofilm, saliva and buccal mucosa, followed by obtaining samples of respiratory secretions for patients with pneumonia, and blood and urine for sepsis). The presence of target microorganisms was performed by polymerase chain reaction (PCR) and culture using selective media. The chi-square and Mann-Whitney tests were used for statistical analysis, and the significance level was 5%. The intraoral clinical conditions of the patients showed poor. E. faecalis was significantly more frequent microorganism, followed by E. faecium. The use of broadspectrum antimicrobial action was associated with the presence of these opportunistic microorganisms. These bacteria were more frequent in patients with periodontitis or gingivitis. The results showed that enterococci associated with serious infectious processes may originate from resident microbiota of patients and its prevalence is not elevated in healthy individuals.