Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/antibiotics12050862 http://hdl.handle.net/11449/248889 |
Resumo: | The emergence of Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections among indigenous populations has been reported. Usually, indigenous communities live in extreme poverty and are at risk of acquiring infections. In Brazil, healthcare inequality is observed in this population. To date, there are no reports of CA-MRSA infections, and no active search for asymptomatic S. aureus carriage has been conducted among Brazilian Indians. The aim of this study was to investigate the prevalence of colonization with S. aureus and CA-MRSA among Brazilian Indians. We screened 400 Indians (from near urban areas and remote hamlets) for S. aureus and CA-MRSA colonization. The isolates were submitted to clonal profiling by pulsed-field gel electrophoresis (PFGE), and selected isolates were submitted to multilocus sequence typing (MLST). Among 931 specimens (nasal and oral) from different indigenous individuals in remote hamlets, S. aureus was cultured in 190 (47.6%). Furthermore, CA-MRSA was found in three isolates (0.7%), all SCCmec type IV. PFGE analysis identified 21 clusters among the S. aureus isolates, and MLST analysis showed a predominance of sequence type 5 among these isolates. Our study revealed a higher prevalence of S. aureus carriage among Shanenawa ethnicity individuals (41.1%). Therefore, ethnicity appears to be associated with the prevalence of S. aureus in these populations. |
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Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communitiesbrazilian indiansCA-MRSAcolonizationethnicityremote communitiesStaphylococcus aureusThe emergence of Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections among indigenous populations has been reported. Usually, indigenous communities live in extreme poverty and are at risk of acquiring infections. In Brazil, healthcare inequality is observed in this population. To date, there are no reports of CA-MRSA infections, and no active search for asymptomatic S. aureus carriage has been conducted among Brazilian Indians. The aim of this study was to investigate the prevalence of colonization with S. aureus and CA-MRSA among Brazilian Indians. We screened 400 Indians (from near urban areas and remote hamlets) for S. aureus and CA-MRSA colonization. The isolates were submitted to clonal profiling by pulsed-field gel electrophoresis (PFGE), and selected isolates were submitted to multilocus sequence typing (MLST). Among 931 specimens (nasal and oral) from different indigenous individuals in remote hamlets, S. aureus was cultured in 190 (47.6%). Furthermore, CA-MRSA was found in three isolates (0.7%), all SCCmec type IV. PFGE analysis identified 21 clusters among the S. aureus isolates, and MLST analysis showed a predominance of sequence type 5 among these isolates. Our study revealed a higher prevalence of S. aureus carriage among Shanenawa ethnicity individuals (41.1%). Therefore, ethnicity appears to be associated with the prevalence of S. aureus in these populations.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Department of Infectology Dermatology Diagnostic Imaging and Radiotherapy Medical School (FMB) Sao Paulo State University (UNESP)Nursing Research and Care Practices Hospital Samaritano HigienopolisCenter of Bacteriology Adolfo Lutz Institute—IALDepartment of Chemical and Biological Sciences Biosciences Institute UNESP—Universidade Estadual PaulistaDepartment of Nursing Federal University of Acre—UFACDepartment of Infectology Dermatology Diagnostic Imaging and Radiotherapy Medical School (FMB) Sao Paulo State University (UNESP)Department of Chemical and Biological Sciences Biosciences Institute UNESP—Universidade Estadual PaulistaCAPES: 110938-3CNPq: 303603/2020-8Universidade Estadual Paulista (UNESP)Hospital Samaritano HigienopolisAdolfo Lutz Institute—IALFederal University of Acre—UFACAbraão, Lígia Maria [UNESP]Fortaleza, Carlos Magno Castelo Branco [UNESP]Camargo, Carlos HenriqueBarbosa, Thaís Alves [UNESP]Pereira-Franchi, Eliane Patrícia Lino [UNESP]Riboli, Danilo Flávio Moraes [UNESP]Hubinger, Luiza [UNESP]Bonesso, Mariana Fávero [UNESP]Medeiros de Souza, RodrigoRibeiro de Souza da Cunha, Maria de Lourdes [UNESP]2023-07-29T13:56:33Z2023-07-29T13:56:33Z2023-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/antibiotics12050862Antibiotics, v. 12, n. 5, 2023.2079-6382http://hdl.handle.net/11449/24888910.3390/antibiotics120508622-s2.0-85160323819Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAntibioticsinfo:eu-repo/semantics/openAccess2024-08-15T15:23:02Zoai:repositorio.unesp.br:11449/248889Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-08-15T15:23:02Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities |
title |
Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities |
spellingShingle |
Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities Abraão, Lígia Maria [UNESP] brazilian indians CA-MRSA colonization ethnicity remote communities Staphylococcus aureus |
title_short |
Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities |
title_full |
Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities |
title_fullStr |
Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities |
title_full_unstemmed |
Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities |
title_sort |
Staphylococcus aureus and CA-MRSA Carriage among Brazilian Indians Living in Peri-Urban Areas and Remote Communities |
author |
Abraão, Lígia Maria [UNESP] |
author_facet |
Abraão, Lígia Maria [UNESP] Fortaleza, Carlos Magno Castelo Branco [UNESP] Camargo, Carlos Henrique Barbosa, Thaís Alves [UNESP] Pereira-Franchi, Eliane Patrícia Lino [UNESP] Riboli, Danilo Flávio Moraes [UNESP] Hubinger, Luiza [UNESP] Bonesso, Mariana Fávero [UNESP] Medeiros de Souza, Rodrigo Ribeiro de Souza da Cunha, Maria de Lourdes [UNESP] |
author_role |
author |
author2 |
Fortaleza, Carlos Magno Castelo Branco [UNESP] Camargo, Carlos Henrique Barbosa, Thaís Alves [UNESP] Pereira-Franchi, Eliane Patrícia Lino [UNESP] Riboli, Danilo Flávio Moraes [UNESP] Hubinger, Luiza [UNESP] Bonesso, Mariana Fávero [UNESP] Medeiros de Souza, Rodrigo Ribeiro de Souza da Cunha, Maria de Lourdes [UNESP] |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Hospital Samaritano Higienopolis Adolfo Lutz Institute—IAL Federal University of Acre—UFAC |
dc.contributor.author.fl_str_mv |
Abraão, Lígia Maria [UNESP] Fortaleza, Carlos Magno Castelo Branco [UNESP] Camargo, Carlos Henrique Barbosa, Thaís Alves [UNESP] Pereira-Franchi, Eliane Patrícia Lino [UNESP] Riboli, Danilo Flávio Moraes [UNESP] Hubinger, Luiza [UNESP] Bonesso, Mariana Fávero [UNESP] Medeiros de Souza, Rodrigo Ribeiro de Souza da Cunha, Maria de Lourdes [UNESP] |
dc.subject.por.fl_str_mv |
brazilian indians CA-MRSA colonization ethnicity remote communities Staphylococcus aureus |
topic |
brazilian indians CA-MRSA colonization ethnicity remote communities Staphylococcus aureus |
description |
The emergence of Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections among indigenous populations has been reported. Usually, indigenous communities live in extreme poverty and are at risk of acquiring infections. In Brazil, healthcare inequality is observed in this population. To date, there are no reports of CA-MRSA infections, and no active search for asymptomatic S. aureus carriage has been conducted among Brazilian Indians. The aim of this study was to investigate the prevalence of colonization with S. aureus and CA-MRSA among Brazilian Indians. We screened 400 Indians (from near urban areas and remote hamlets) for S. aureus and CA-MRSA colonization. The isolates were submitted to clonal profiling by pulsed-field gel electrophoresis (PFGE), and selected isolates were submitted to multilocus sequence typing (MLST). Among 931 specimens (nasal and oral) from different indigenous individuals in remote hamlets, S. aureus was cultured in 190 (47.6%). Furthermore, CA-MRSA was found in three isolates (0.7%), all SCCmec type IV. PFGE analysis identified 21 clusters among the S. aureus isolates, and MLST analysis showed a predominance of sequence type 5 among these isolates. Our study revealed a higher prevalence of S. aureus carriage among Shanenawa ethnicity individuals (41.1%). Therefore, ethnicity appears to be associated with the prevalence of S. aureus in these populations. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T13:56:33Z 2023-07-29T13:56:33Z 2023-05-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/antibiotics12050862 Antibiotics, v. 12, n. 5, 2023. 2079-6382 http://hdl.handle.net/11449/248889 10.3390/antibiotics12050862 2-s2.0-85160323819 |
url |
http://dx.doi.org/10.3390/antibiotics12050862 http://hdl.handle.net/11449/248889 |
identifier_str_mv |
Antibiotics, v. 12, n. 5, 2023. 2079-6382 10.3390/antibiotics12050862 2-s2.0-85160323819 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Antibiotics |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
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1826304208491511808 |