Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/nu11092051 http://hdl.handle.net/11449/196203 |
Resumo: | Protein supplements are usually used to control body weight, however, the impact of protein quality on body fat attenuation is unknown. We investigated the effects of isocaloric isoproteic supplementation of either whey protein (WG) or hydrolysed collagen supplementation (CG) on dietary intake, adiposity and biochemical markers in overweight women. Methods: In this randomized double-blind study, 37 women, [mean +/- SE, age 40.6 +/- 1.7 year; BMI (kg/m(2)) 30.9 +/- 0.6], consumed sachets containing 40 g/day of concentrated whey protein (25 g total protein, 2.4 leucine, 1.0 valine, 1.5 isoleucine, n = 17) or 38 g/day of hydrolysed collagen (26 g total protein, 1.02 leucine, 0.91 valine, 0.53 isoleucine, n = 20) in the afternoon snack. The compliance was set at >70% of the total theoretical doses. The dietary intake was evaluated by a 6-day food record questionnaire. At the beginning and after eight weeks of follow-up, body composition was evaluated by using dual-energy X-ray absorptiometry and lipid profile, insulin resistance, C-reactive protein, adiponectin, leptin and nesfastin plasma concentrations were analyzed. Results: Supplements were isocaloric and isoproteic. There were no differences in caloric intake (p = 0.103), protein (p = 0.085), carbohydrate (p = 0.797) and lipids (p = 0.109) intakes. The branched chain amino acids (BCAA) (GC: 1.8 +/- 0.1 g vs. WG: 5.5 +/- 0.3 g, p < 0.001) and leucine intake (CG: 0.1 +/- 0.1 g vs. WG: 2.6 +/- 0.1 g, p < 0.001) were higher in WG compared to CG. BMI increased in the CG (0.2 +/- 1.1 kg/m(2), p = 0.044) but did not change in WG. WG decreased the android fat (-0.1 +/- 0.3 kg, p = 0.031) and increased nesfatin concentrations (4.9 +/- 3.2 ng/mL, p = 0.014) compared to CG. Conclusions: Whey protein supplementation in overweight women increased nesfatin concentrations and could promote increase of resting metabolic rate as part of body composition improvement programs compared to collagen supplementation for 8 weeks. Additionally, our findings suggest that collagen may not be an effective supplement for overweight women who are attempting to alter body composition. |
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Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Studyobesitywhey proteincollagenweight lossleucineamino acidsProtein supplements are usually used to control body weight, however, the impact of protein quality on body fat attenuation is unknown. We investigated the effects of isocaloric isoproteic supplementation of either whey protein (WG) or hydrolysed collagen supplementation (CG) on dietary intake, adiposity and biochemical markers in overweight women. Methods: In this randomized double-blind study, 37 women, [mean +/- SE, age 40.6 +/- 1.7 year; BMI (kg/m(2)) 30.9 +/- 0.6], consumed sachets containing 40 g/day of concentrated whey protein (25 g total protein, 2.4 leucine, 1.0 valine, 1.5 isoleucine, n = 17) or 38 g/day of hydrolysed collagen (26 g total protein, 1.02 leucine, 0.91 valine, 0.53 isoleucine, n = 20) in the afternoon snack. The compliance was set at >70% of the total theoretical doses. The dietary intake was evaluated by a 6-day food record questionnaire. At the beginning and after eight weeks of follow-up, body composition was evaluated by using dual-energy X-ray absorptiometry and lipid profile, insulin resistance, C-reactive protein, adiponectin, leptin and nesfastin plasma concentrations were analyzed. Results: Supplements were isocaloric and isoproteic. There were no differences in caloric intake (p = 0.103), protein (p = 0.085), carbohydrate (p = 0.797) and lipids (p = 0.109) intakes. The branched chain amino acids (BCAA) (GC: 1.8 +/- 0.1 g vs. WG: 5.5 +/- 0.3 g, p < 0.001) and leucine intake (CG: 0.1 +/- 0.1 g vs. WG: 2.6 +/- 0.1 g, p < 0.001) were higher in WG compared to CG. BMI increased in the CG (0.2 +/- 1.1 kg/m(2), p = 0.044) but did not change in WG. WG decreased the android fat (-0.1 +/- 0.3 kg, p = 0.031) and increased nesfatin concentrations (4.9 +/- 3.2 ng/mL, p = 0.014) compared to CG. Conclusions: Whey protein supplementation in overweight women increased nesfatin concentrations and could promote increase of resting metabolic rate as part of body composition improvement programs compared to collagen supplementation for 8 weeks. Additionally, our findings suggest that collagen may not be an effective supplement for overweight women who are attempting to alter body composition.Univ Fed Goias, Fac Nutr, Clin & Sports Nutr Res Lab Labince, BR-74605080 Goiania, Go, BrazilUniv Estadual Paulista, Dept Phys Educ, Postgrad Program Movement Sci, Exercise & Immunometab Res Grp, BR-19060900 Presidente Prudente, SP, BrazilGeneva Univ Hosp, Clin Nutr, CH-1205 Geneva, SwitzerlandUniv Estadual Paulista, Dept Phys Educ, Postgrad Program Movement Sci, Exercise & Immunometab Res Grp, BR-19060900 Presidente Prudente, SP, BrazilMdpiUniversidade Federal de Goiás (UFG)Universidade Estadual Paulista (Unesp)Geneva Univ HospGiglio, Bruna M.Schincaglia, Raquel M.Silva, Alexandre S. daFazani, Ieda C. S.Monteiro, Paula A. [UNESP]Mota, Joao F.Cunha, Juliana P.Pichard, ClaudePimentel, Gustavo D.2020-12-10T19:36:52Z2020-12-10T19:36:52Z2019-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article14http://dx.doi.org/10.3390/nu11092051Nutrients. Basel: Mdpi, v. 11, n. 9, 14 p., 2019.http://hdl.handle.net/11449/19620310.3390/nu11092051WOS:000487964600237Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengNutrientsinfo:eu-repo/semantics/openAccess2024-06-18T17:42:58Zoai:repositorio.unesp.br:11449/196203Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:25:21.033698Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study |
title |
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study |
spellingShingle |
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study Giglio, Bruna M. obesity whey protein collagen weight loss leucine amino acids |
title_short |
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study |
title_full |
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study |
title_fullStr |
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study |
title_full_unstemmed |
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study |
title_sort |
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study |
author |
Giglio, Bruna M. |
author_facet |
Giglio, Bruna M. Schincaglia, Raquel M. Silva, Alexandre S. da Fazani, Ieda C. S. Monteiro, Paula A. [UNESP] Mota, Joao F. Cunha, Juliana P. Pichard, Claude Pimentel, Gustavo D. |
author_role |
author |
author2 |
Schincaglia, Raquel M. Silva, Alexandre S. da Fazani, Ieda C. S. Monteiro, Paula A. [UNESP] Mota, Joao F. Cunha, Juliana P. Pichard, Claude Pimentel, Gustavo D. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de Goiás (UFG) Universidade Estadual Paulista (Unesp) Geneva Univ Hosp |
dc.contributor.author.fl_str_mv |
Giglio, Bruna M. Schincaglia, Raquel M. Silva, Alexandre S. da Fazani, Ieda C. S. Monteiro, Paula A. [UNESP] Mota, Joao F. Cunha, Juliana P. Pichard, Claude Pimentel, Gustavo D. |
dc.subject.por.fl_str_mv |
obesity whey protein collagen weight loss leucine amino acids |
topic |
obesity whey protein collagen weight loss leucine amino acids |
description |
Protein supplements are usually used to control body weight, however, the impact of protein quality on body fat attenuation is unknown. We investigated the effects of isocaloric isoproteic supplementation of either whey protein (WG) or hydrolysed collagen supplementation (CG) on dietary intake, adiposity and biochemical markers in overweight women. Methods: In this randomized double-blind study, 37 women, [mean +/- SE, age 40.6 +/- 1.7 year; BMI (kg/m(2)) 30.9 +/- 0.6], consumed sachets containing 40 g/day of concentrated whey protein (25 g total protein, 2.4 leucine, 1.0 valine, 1.5 isoleucine, n = 17) or 38 g/day of hydrolysed collagen (26 g total protein, 1.02 leucine, 0.91 valine, 0.53 isoleucine, n = 20) in the afternoon snack. The compliance was set at >70% of the total theoretical doses. The dietary intake was evaluated by a 6-day food record questionnaire. At the beginning and after eight weeks of follow-up, body composition was evaluated by using dual-energy X-ray absorptiometry and lipid profile, insulin resistance, C-reactive protein, adiponectin, leptin and nesfastin plasma concentrations were analyzed. Results: Supplements were isocaloric and isoproteic. There were no differences in caloric intake (p = 0.103), protein (p = 0.085), carbohydrate (p = 0.797) and lipids (p = 0.109) intakes. The branched chain amino acids (BCAA) (GC: 1.8 +/- 0.1 g vs. WG: 5.5 +/- 0.3 g, p < 0.001) and leucine intake (CG: 0.1 +/- 0.1 g vs. WG: 2.6 +/- 0.1 g, p < 0.001) were higher in WG compared to CG. BMI increased in the CG (0.2 +/- 1.1 kg/m(2), p = 0.044) but did not change in WG. WG decreased the android fat (-0.1 +/- 0.3 kg, p = 0.031) and increased nesfatin concentrations (4.9 +/- 3.2 ng/mL, p = 0.014) compared to CG. Conclusions: Whey protein supplementation in overweight women increased nesfatin concentrations and could promote increase of resting metabolic rate as part of body composition improvement programs compared to collagen supplementation for 8 weeks. Additionally, our findings suggest that collagen may not be an effective supplement for overweight women who are attempting to alter body composition. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-09-01 2020-12-10T19:36:52Z 2020-12-10T19:36:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/nu11092051 Nutrients. Basel: Mdpi, v. 11, n. 9, 14 p., 2019. http://hdl.handle.net/11449/196203 10.3390/nu11092051 WOS:000487964600237 |
url |
http://dx.doi.org/10.3390/nu11092051 http://hdl.handle.net/11449/196203 |
identifier_str_mv |
Nutrients. Basel: Mdpi, v. 11, n. 9, 14 p., 2019. 10.3390/nu11092051 WOS:000487964600237 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Nutrients |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
14 |
dc.publisher.none.fl_str_mv |
Mdpi |
publisher.none.fl_str_mv |
Mdpi |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128808063074304 |