Avaliação da eficácia de um gel com reduzida concentração de fluoreto e suplementado com hexametafosfato em inibir a desmineralização do esmalte dentário: estudo in vitro

• Autor(a) principal: Scarpa, Josiane Braga [UNESP]
• Data de Publicação: 2011
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/149329; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2017-01-26/000838814.pdf
• topic: Esmalte dentário; Flúor; Fosfatos; Desmineralização do dente; Dental enamel

The decline of tooth decay in recent decades has been attributed to widespread use of fluoride (F) in various forms of presentation and application. The application of fluoride gel is intended to make the formation of calcium fluoride (CaF2) which would remain in contact with the enamel for a longer period, but its high concentration of F also brings increased risk of acute poisoning. The purpose of this study was to evaluate in vitro whether supplementation of a gel of low concentration of F with hexametaphosphate (HMP) results in an ability to reduce the demineralization of tooth enamel comparable to a standard gel of higher concentration of F. Blocks (n=120) of bovine enamel were selected by measuring the surface hardness (SH1) and divided into six experimental groups (n = 20) treated with the following gels: 1) placebo gel without F and HMP (control group); 2) 9% HMP gel; 3) 4500 μgF/g gel; 4) 4500 μgF/g + 9% HMP gel; 5) 9000 μgF/g gel; 6) 12,300 μgF/g acid gel. The blocks were treated with the respective gels during one minute. Ten blocks of each group were analyzed for concentration of CaF2 formed. The other ten blocks were subjected to five pH-cycling (pH 4.7/ 6h and pH 7.0/18h) during 7 days. After pH-cycling the final surface hardness (SH2) was measured and the percentage of surface hardness alteration was calculated. The concentration of CaF2 retained was also determined. The results were submitted to analysis of variance followed by Bonferroni test (p <0.05). The treatment with gel containing 4,500 μgF/g + 9% HMP resulted in a percentage of surface hardness alteration lower than the non supplemented group (p<0.05) and similar to 9000 μgF/g and acid gel groups (p> 0.05). The concentration of CaF2 formed was higher than non supplemented group, however, lower than 9000 μgF/g and acid gel groups (p> 0.05). The latter showed...