Antiplasmodial Natural Products

Detalhes bibliográficos
Autor(a) principal: Nogueira, Claudio R. [UNESP]
Data de Publicação: 2011
Outros Autores: Lopes, Lucia Maria Xavier [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3390/molecules16032146
http://hdl.handle.net/11449/26161
Resumo: Malaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial activity as potential sources of new antimalarial drugs. This review highlights studies on natural products with antimalarial and antiplasmodial activity reported in the literature from January 2009 to November 2010. A total of 360 antiplasmodial natural products comprised of terpenes, including iridoids, sesquiterpenes, diterpenes, terpenoid benzoquinones, steroids, quassinoids, limonoids, curcubitacins, and lanostanes; flavonoids; alkaloids; peptides; phenylalkanoids; xanthones; naphthopyrones; polyketides, including halenaquinones, peroxides, polyacetylenes, and resorcylic acids; depsidones; benzophenones; macrolides; and miscellaneous compounds, including halogenated compounds and chromenes are listed in this review.
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spelling Antiplasmodial Natural ProductsmalariaantimalarialantiplasmodialPlasmodiumMalaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial activity as potential sources of new antimalarial drugs. This review highlights studies on natural products with antimalarial and antiplasmodial activity reported in the literature from January 2009 to November 2010. A total of 360 antiplasmodial natural products comprised of terpenes, including iridoids, sesquiterpenes, diterpenes, terpenoid benzoquinones, steroids, quassinoids, limonoids, curcubitacins, and lanostanes; flavonoids; alkaloids; peptides; phenylalkanoids; xanthones; naphthopyrones; polyketides, including halenaquinones, peroxides, polyacetylenes, and resorcylic acids; depsidones; benzophenones; macrolides; and miscellaneous compounds, including halogenated compounds and chromenes are listed in this review.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Estadual Paulista, UNESP, Inst Quim, BR-14801970 Araraquara, SP, BrazilUniv Estadual Paulista, UNESP, Inst Quim, BR-14801970 Araraquara, SP, BrazilCNPq: 555675/2009-2CNPq: 575746/2008-4Mdpi AgUniversidade Estadual Paulista (Unesp)Nogueira, Claudio R. [UNESP]Lopes, Lucia Maria Xavier [UNESP]2014-05-20T14:20:30Z2014-05-20T14:20:30Z2011-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2146-2190application/pdfhttp://dx.doi.org/10.3390/molecules16032146Molecules. Basel: Mdpi Ag, v. 16, n. 3, p. 2146-2190, 2011.1420-3049http://hdl.handle.net/11449/2616110.3390/molecules16032146WOS:000288853400017WOS000288853400017.pdf5981353442037051Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMolecules3.0980,855info:eu-repo/semantics/openAccess2024-12-04T14:10:42Zoai:repositorio.unesp.br:11449/26161Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-12-04T14:10:42Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Antiplasmodial Natural Products
title Antiplasmodial Natural Products
spellingShingle Antiplasmodial Natural Products
Nogueira, Claudio R. [UNESP]
malaria
antimalarial
antiplasmodial
Plasmodium
title_short Antiplasmodial Natural Products
title_full Antiplasmodial Natural Products
title_fullStr Antiplasmodial Natural Products
title_full_unstemmed Antiplasmodial Natural Products
title_sort Antiplasmodial Natural Products
author Nogueira, Claudio R. [UNESP]
author_facet Nogueira, Claudio R. [UNESP]
Lopes, Lucia Maria Xavier [UNESP]
author_role author
author2 Lopes, Lucia Maria Xavier [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Nogueira, Claudio R. [UNESP]
Lopes, Lucia Maria Xavier [UNESP]
dc.subject.por.fl_str_mv malaria
antimalarial
antiplasmodial
Plasmodium
topic malaria
antimalarial
antiplasmodial
Plasmodium
description Malaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial activity as potential sources of new antimalarial drugs. This review highlights studies on natural products with antimalarial and antiplasmodial activity reported in the literature from January 2009 to November 2010. A total of 360 antiplasmodial natural products comprised of terpenes, including iridoids, sesquiterpenes, diterpenes, terpenoid benzoquinones, steroids, quassinoids, limonoids, curcubitacins, and lanostanes; flavonoids; alkaloids; peptides; phenylalkanoids; xanthones; naphthopyrones; polyketides, including halenaquinones, peroxides, polyacetylenes, and resorcylic acids; depsidones; benzophenones; macrolides; and miscellaneous compounds, including halogenated compounds and chromenes are listed in this review.
publishDate 2011
dc.date.none.fl_str_mv 2011-03-01
2014-05-20T14:20:30Z
2014-05-20T14:20:30Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3390/molecules16032146
Molecules. Basel: Mdpi Ag, v. 16, n. 3, p. 2146-2190, 2011.
1420-3049
http://hdl.handle.net/11449/26161
10.3390/molecules16032146
WOS:000288853400017
WOS000288853400017.pdf
5981353442037051
url http://dx.doi.org/10.3390/molecules16032146
http://hdl.handle.net/11449/26161
identifier_str_mv Molecules. Basel: Mdpi Ag, v. 16, n. 3, p. 2146-2190, 2011.
1420-3049
10.3390/molecules16032146
WOS:000288853400017
WOS000288853400017.pdf
5981353442037051
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Molecules
3.098
0,855
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 2146-2190
application/pdf
dc.publisher.none.fl_str_mv Mdpi Ag
publisher.none.fl_str_mv Mdpi Ag
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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