Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/s0102-865020200070000001 http://hdl.handle.net/11449/200915 |
Resumo: | Purpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks. |
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Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogsAnalgesiaBupivacaineDogsLidocaineSurgical WoundsPurpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Clinical and Veterinary Surgery Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista (FCAV-UNESP)FCAV-UNESPUnião das Faculdades dos Grandes Lagos (UNILAGO)Department of Clinical and Veterinary Surgery Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista (FCAV-UNESP)FCAV-UNESPFAPESP: 2015/24955-5Universidade Estadual Paulista (Unesp)União das Faculdades dos Grandes Lagos (UNILAGO)Minto, Bruno Watanabe [UNESP]Zanato, Laura [UNESP]Franco, Guilherme Galhardo [UNESP]Kawamoto, Fernando Yoiti Kitamura [UNESP]Borsaro, Camila Potério [UNESP]Pazzini, Josiane MoraisCarvalho, Elizabeth Regina [UNESP]Matsui, Andresa [UNESP]2020-12-12T02:19:28Z2020-12-12T02:19:28Z2020-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-8application/pdfhttp://dx.doi.org/10.1590/s0102-865020200070000001Acta Cirurgica Brasileira, v. 35, n. 7, p. 1-8, 2020.1678-26740102-8650http://hdl.handle.net/11449/20091510.1590/s0102-865020200070000001S0102-865020200007002022-s2.0-85089551346S0102-86502020000700202.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Cirurgica Brasileirainfo:eu-repo/semantics/openAccess2024-01-16T06:25:30Zoai:repositorio.unesp.br:11449/200915Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-16T06:25:30Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
spellingShingle |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs Minto, Bruno Watanabe [UNESP] Analgesia Bupivacaine Dogs Lidocaine Surgical Wounds |
title_short |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_full |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_fullStr |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_full_unstemmed |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_sort |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
author |
Minto, Bruno Watanabe [UNESP] |
author_facet |
Minto, Bruno Watanabe [UNESP] Zanato, Laura [UNESP] Franco, Guilherme Galhardo [UNESP] Kawamoto, Fernando Yoiti Kitamura [UNESP] Borsaro, Camila Potério [UNESP] Pazzini, Josiane Morais Carvalho, Elizabeth Regina [UNESP] Matsui, Andresa [UNESP] |
author_role |
author |
author2 |
Zanato, Laura [UNESP] Franco, Guilherme Galhardo [UNESP] Kawamoto, Fernando Yoiti Kitamura [UNESP] Borsaro, Camila Potério [UNESP] Pazzini, Josiane Morais Carvalho, Elizabeth Regina [UNESP] Matsui, Andresa [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) União das Faculdades dos Grandes Lagos (UNILAGO) |
dc.contributor.author.fl_str_mv |
Minto, Bruno Watanabe [UNESP] Zanato, Laura [UNESP] Franco, Guilherme Galhardo [UNESP] Kawamoto, Fernando Yoiti Kitamura [UNESP] Borsaro, Camila Potério [UNESP] Pazzini, Josiane Morais Carvalho, Elizabeth Regina [UNESP] Matsui, Andresa [UNESP] |
dc.subject.por.fl_str_mv |
Analgesia Bupivacaine Dogs Lidocaine Surgical Wounds |
topic |
Analgesia Bupivacaine Dogs Lidocaine Surgical Wounds |
description |
Purpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T02:19:28Z 2020-12-12T02:19:28Z 2020-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/s0102-865020200070000001 Acta Cirurgica Brasileira, v. 35, n. 7, p. 1-8, 2020. 1678-2674 0102-8650 http://hdl.handle.net/11449/200915 10.1590/s0102-865020200070000001 S0102-86502020000700202 2-s2.0-85089551346 S0102-86502020000700202.pdf |
url |
http://dx.doi.org/10.1590/s0102-865020200070000001 http://hdl.handle.net/11449/200915 |
identifier_str_mv |
Acta Cirurgica Brasileira, v. 35, n. 7, p. 1-8, 2020. 1678-2674 0102-8650 10.1590/s0102-865020200070000001 S0102-86502020000700202 2-s2.0-85089551346 S0102-86502020000700202.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Acta Cirurgica Brasileira |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-8 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799965632333086720 |